1.
Bioorg Med Chem Lett
; 21(21): 6515-8, 2011 Nov 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21924901
RESUMO
A series of acidic triazoles with activity as soluble guanylate cyclase stimulators is described. Incorporation of the CF(3) triazole improved the overall physicochemical and drug-like properties of the molecule and is exemplified by compound 25.