Pesquisa | BVS Violência e Saúde

1.

Comparison of triazines as inhibitors of L1210 dihydrofolate reductase and of L1210 cells sensitive and resistant to methotrexate.

Selassie, C D; Strong, C D; Hansch, C; Delcamp, T J; Freisheim, J H; Khwaja, T A.

Cancer Res ; 46(2): 744-56, 1986 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-3940640

2.

Human placental alkaline phosphatase in benign and malignant ovarian neoplasia.

Nouwen, E J; Pollet, D E; Schelstraete, J B; Eerdekens, M W; Hänsch, C; Van de Voorde, A; De Broe, M E.

Cancer Res ; 45(2): 892-902, 1985 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-3967249

3.

The structure-activity relationship of the papain hydrolysis of N-benzoylglycine esters.

Compadre, C M; Hansch, C; Klein, T E; Langridge, R.

Biochim Biophys Acta ; 1038(2): 158-63, 1990 Apr 19.

Artigo em Inglês | MEDLINE | ID: mdl-2331480

4.

Separation of electronic and hydrophobic effects for the papain hydrolysis of substituted N-benzoylglycine esters.

Compadre, C M; Hansch, C; Klein, T E; Petridou-Fischer, J; Selassie, C D; Smith, R N; Steinmetz, W; Yang, C Z; Yang, G Z.

Biochim Biophys Acta ; 1079(1): 43-52, 1991 Aug 09.

Artigo em Inglês | MEDLINE | ID: mdl-1888764

5.

Selective inhibition of Leishmania dihydrofolate reductase and Leishmania growth by 5-benzyl-2,4-diaminopyrimidines.

Sirawaraporn, W; Sertsrivanich, R; Booth, R G; Hansch, C; Neal, R A; Santi, D V.

Mol Biochem Parasitol ; 31(1): 79-85, 1988 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-3185614

6.

On the structure of medicinal chemistry.

Hansch, C.

J Med Chem ; 19(1): 1-6, 1976 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-1246029

7.

Correlation analysis of Baker's studies on enzyme inhibition. 2. Chymotrypsin, trypsin, thymidine phosphorylase, uridine phosphorylase, thymidylate synthetase, cytosine nucleoside deaminase, dihydrofolate reductase, malate dehydrogenase, glutamate dehydrogenase, lactate dehydrogenase, and glyceraldehyde-phosphate dehydrogenase.

Yoshimoto, M; Hansch, C.

J Med Chem ; 19(1): 71-98, 1976 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-1107550

8.

Correlation analysis of Baker's studies on enzyme inhibition. 1. Guanine deaminase, xanthine oxidase, dihydrofolate reductase, and complement.

Silipo, C; Hansch, C.

J Med Chem ; 19(1): 62-71, 1976 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-1246055

9.

Structure-activity relationships in antitumor aniline mustards.

Panthananickal, A; Hansch, C; Leo, A.

J Med Chem ; 21(1): 16-26, 1978 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-619146

10.

Structure-activity relationship of aniline mustards acting against B-16 melanoma in mice.

Panthananickal, A; Hansch, C; Leo, A.

J Med Chem ; 22(10): 1267-9, 1979 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-513075

11.

Structure-activity relationship of the ficin hydrolysis of phenyl hippurates. Comparison with papain, actinidin, and bromelain.

Carotti, A; Casini, G; Hansch, C.

J Med Chem ; 27(11): 1427-31, 1984 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-6387120

12.

Mutagenicity of substituted (o-phenylenediamine)platinum dichloride in the Ames test. A quantitative structure-activity analysis.

Hansch, C; Venger, B H; Panthananickal, A.

J Med Chem ; 23(4): 459-61, 1980 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-6991694

13.

Structure-activity relationship in synthetic fibrinolytics. 2-Phenethynylcyclopropanecarboxylates.

Yoshimoto, M; von Kaulla, K N; Hansch, C.

J Med Chem ; 18(9): 950-1, 1975 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-1159718

14.

A comparison of the inhibitory action of 5-(substituted-benzyl)-2,4-diaminopyrimidines on dihydrofolate reductase from chicken liver with that from bovine liver.

Li, R; Hansch, C; Kaufman, B T.

J Med Chem ; 25(4): 435-40, 1982 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-7069722

15.

Quantitative structure-selectivity relationships. Comparison of the inhibition of Escherichia coli and bovine liver dihydrofolate reductase by 5-(substituted-benzyl)-2,4-diaminopyrimidines.

Li, R L; Dietrich, S W; Hansch, C.

J Med Chem ; 24(5): 538-44, 1981 May.

Artigo em Inglês | MEDLINE | ID: mdl-7017146

16.

Structure-activity relationships of antineoplastic agents in multidrug resistance.

Selassie, C D; Hansch, C; Khwaja, T A.

J Med Chem ; 33(7): 1914-9, 1990 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-2362268

17.

Quantitative structure-activity relationships of antimalarial and dihydrofolate reductase inhibition by quinazolines and 5-substituted benzyl-2,4-diaminopyrimidines.

Hansch, C; Fukunaga, J Y; Jow, P Y.

J Med Chem ; 20(1): 96-102, 1977 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-319234

18.

Inhibition of dihydrofolate reductase. Structure-activity correlations of quinazolines.

Fukunaga, J Y; Hansch, C; Steller, E E.

J Med Chem ; 19(5): 605-11, 1976 May.

Artigo em Inglês | MEDLINE | ID: mdl-1271401

19.

Dependence of hydrophobicity of apolar molecules on their molecular volume.

Leo, A; Hansch, C; Jow, P Y.

J Med Chem ; 19(5): 611-5, 1976 May.

Artigo em Inglês | MEDLINE | ID: mdl-1271402

20.

Quantitative structure-activity relationship of chymotrypsin-ligand interactions.

Hansch, C; Grieco, C; Silipo, C; Vittoria, A.

J Med Chem ; 20(11): 1420-35, 1977 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-915902

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