Pesquisa | BVS Violência e Saúde

1.

Lipid kinase PIK3C3 maintains healthy brown and white adipose tissues to prevent metabolic diseases.

Song, Wenqiang; Postoak, J Luke; Yang, Guan; Guo, Xingyi; Pua, Heather H; Bader, Jackie; Rathmell, Jeffrey C; Kobayashi, Hanako; Haase, Volker H; Leaptrot, Katrina L; Schrimpe-Rutledge, Alexandra C; Sherrod, Stacy D; McLean, John A; Zhang, Jianhua; Wu, Lan; Van Kaer, Luc.

Proc Natl Acad Sci U S A ; 120(1): e2214874120, 2023 01 03.

Artigo em Inglês | MEDLINE | ID: mdl-36574710

2.

Deregulating iron-erythropoiesis regulation: transferrin receptor 2 as potential target for treating anemia in CKD.

Koury, Mark J; Haase, Volker H.

Kidney Int ; 104(1): 25-28, 2023 07.

Artigo em Inglês | MEDLINE | ID: mdl-37349056

3.

Novel anemia therapies in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Ku, Elaine; Del Vecchio, Lucia; Eckardt, Kai-Uwe; Haase, Volker H; Johansen, Kirsten L; Nangaku, Masaomi; Tangri, Navdeep; Waikar, Sushrut S; Wiecek, Andrzej; Cheung, Michael; Jadoul, Michel; Winkelmayer, Wolfgang C; Wheeler, David C.

Kidney Int ; 104(4): 655-680, 2023 10.

Artigo em Inglês | MEDLINE | ID: mdl-37236424

4.

Epidermal sensing of oxygen is essential for systemic hypoxic response.

Boutin, Adam T; Weidemann, Alexander; Fu, Zhenxing; Mesropian, Lernik; Gradin, Katarina; Jamora, Colin; Wiesener, Michael; Eckardt, Kai-Uwe; Koch, Cameron J; Ellies, Lesley G; Haddad, Gabriel; Haase, Volker H; Simon, M Celeste; Poellinger, Lorenz; Powell, Frank L; Johnson, Randall S.

Cell ; 133(2): 223-34, 2008 Apr 18.

Artigo em Inglês | MEDLINE | ID: mdl-18423195

5.

Inhibition of hypoxia-inducible factor-prolyl hydroxylation protects from cyclophosphamide-induced bladder injury and urinary dysfunction.

Clayton, Douglass B; Tong, Ching Man Carmen; Li, Belinda; Taylor, Abby S; De, Shuvro; Mason, Matthew D; Dudley, Anne G; Davidoff, Olena; Kobayashi, Hanako; Haase, Volker H.

Am J Physiol Renal Physiol ; 323(1): F81-F91, 2022 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-35499237

6.

The ins and outs of ferric citrate.

Haase, Volker H.

Kidney Int ; 101(4): 668-670, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-35314048

7.

Disruption of mitochondrial complex III in cap mesenchyme but not in ureteric progenitors results in defective nephrogenesis associated with amino acid deficiency.

Guan, Nan; Kobayashi, Hanako; Ishii, Ken; Davidoff, Olena; Sha, Feng; Ikizler, Talat A; Hao, Chuan-Ming; Chandel, Navdeep S; Haase, Volker H.

Kidney Int ; 102(1): 108-120, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-35341793

8.

Erythropoietic effects of vadadustat in patients with anemia associated with chronic kidney disease.

Koury, Mark J; Agarwal, Rajiv; Chertow, Glenn M; Eckardt, Kai-Uwe; Fishbane, Steven; Ganz, Tomas; Haase, Volker H; Hanudel, Mark R; Parfrey, Patrick S; Pergola, Pablo E; Roy-Chaudhury, Prabir; Tumlin, James A; Anders, Robert; Farag, Youssef M K; Luo, Wenli; Minga, Todd; Solinsky, Christine; Vargo, Dennis L; Winkelmayer, Wolfgang C.

Am J Hematol ; 97(9): 1178-1188, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-35751858

9.

Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system.

Cho, Sung Hoon; Raybuck, Ariel L; Stengel, Kristy; Wei, Mei; Beck, Thomas C; Volanakis, Emmanuel; Thomas, James W; Hiebert, Scott; Haase, Volker H; Boothby, Mark R.

Nature ; 537(7619): 234-238, 2016 09 08.

Artigo em Inglês | MEDLINE | ID: mdl-27501247

10.

Hypoxia-inducible factors in CD4⁺ T cells promote metabolism, switch cytokine secretion, and T cell help in humoral immunity.

Cho, Sung Hoon; Raybuck, Ariel L; Blagih, Julianna; Kemboi, Edna; Haase, Volker H; Jones, Russell G; Boothby, Mark R.

Proc Natl Acad Sci U S A ; 116(18): 8975-8984, 2019 04 30.

Artigo em Inglês | MEDLINE | ID: mdl-30988188

11.

Stabilization of hypoxia-inducible factor ameliorates glomerular injury sensitization after tubulointerstitial injury.

Zou, Jun; Yang, Jaewon; Zhu, Xiaoye; Zhong, Jianyong; Elshaer, Ahmed; Matsusaka, Taiji; Pastan, Ira; Haase, Volker H; Yang, Hai-Chun; Fogo, Agnes B.

Kidney Int ; 99(3): 620-631, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-33137336

12.

Controversies in optimal anemia management: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference.

Babitt, Jodie L; Eisenga, Michele F; Haase, Volker H; Kshirsagar, Abhijit V; Levin, Adeera; Locatelli, Francesco; Malyszko, Jolanta; Swinkels, Dorine W; Tarng, Der-Cherng; Cheung, Michael; Jadoul, Michel; Winkelmayer, Wolfgang C; Drüeke, Tilman B.

Kidney Int ; 99(6): 1280-1295, 2021 06.

Artigo em Inglês | MEDLINE | ID: mdl-33839163

13.

Kidney epithelial targeted mitochondrial transcription factor A deficiency results in progressive mitochondrial depletion associated with severe cystic disease.

Ishii, Ken; Kobayashi, Hanako; Taguchi, Kensei; Guan, Nan; Li, Andraia; Tong, Carmen; Davidoff, Olena; Tran, Pamela V; Sharma, Madhulika; Chandel, Navdeep S; Kapp, Meghan E; Fogo, Agnes B; Brooks, Craig R; Haase, Volker H.

Kidney Int ; 99(3): 657-670, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-33159962

14.

Got glycogen? An energy resource in HIF-mediated prevention of ischemic kidney injury.

Haase, Volker H.

Kidney Int ; 97(4): 645-647, 2020 04.

Artigo em Inglês | MEDLINE | ID: mdl-32200856

15.

Effects of vadadustat on hemoglobin concentrations in patients receiving hemodialysis previously treated with erythropoiesis-stimulating agents.

Haase, Volker H; Chertow, Glenn M; Block, Geoffrey A; Pergola, Pablo E; deGoma, Emil M; Khawaja, Zeeshan; Sharma, Amit; Maroni, Bradley J; McCullough, Peter A.

Nephrol Dial Transplant ; 34(1): 90-99, 2019 01 01.

Artigo em Inglês | MEDLINE | ID: mdl-29672740

16.

Prolyl-4-hydroxylase 2 and 3 coregulate murine erythropoietin in brain pericytes.

Urrutia, Andres A; Afzal, Aqeela; Nelson, Jacob; Davidoff, Olena; Gross, Kenneth W; Haase, Volker H.

Blood ; 128(21): 2550-2560, 2016 11 24.

Artigo em Inglês | MEDLINE | ID: mdl-27683416

17.

Therapeutic targeting of the HIF oxygen-sensing pathway: Lessons learned from clinical studies.

Haase, Volker H.

Exp Cell Res ; 356(2): 160-165, 2017 07 15.

Artigo em Inglês | MEDLINE | ID: mdl-28483447

18.

Hypoxia-inducible factor prolyl-4-hydroxylation in FOXD1 lineage cells is essential for normal kidney development.

Kobayashi, Hanako; Liu, Jiao; Urrutia, Andres A; Burmakin, Mikhail; Ishii, Ken; Rajan, Malini; Davidoff, Olena; Saifudeen, Zubaida; Haase, Volker H.

Kidney Int ; 92(6): 1370-1383, 2017 12.

Artigo em Inglês | MEDLINE | ID: mdl-28847650

19.

Endothelial HIF signaling regulates pulmonary fibrosis-associated pulmonary hypertension.

Bryant, Andrew J; Carrick, Ryan P; McConaha, Melinda E; Jones, Brittany R; Shay, Sheila D; Moore, Christy S; Blackwell, Thomas R; Gladson, Santhi; Penner, Niki L; Burman, Ankita; Tanjore, Harikrishna; Hemnes, Anna R; Karwandyar, Ayub K; Polosukhin, Vasiliy V; Talati, Megha A; Dong, Hui-Jia; Gleaves, Linda A; Carrier, Erica J; Gaskill, Christa; Scott, Edward W; Majka, Susan M; Fessel, Joshua P; Haase, Volker H; West, James D; Blackwell, Timothy S; Lawson, William E.

Am J Physiol Lung Cell Mol Physiol ; 310(3): L249-62, 2016 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-26637636

20.

Vadadustat, a novel oral HIF stabilizer, provides effective anemia treatment in nondialysis-dependent chronic kidney disease.

Pergola, Pablo E; Spinowitz, Bruce S; Hartman, Charlotte S; Maroni, Bradley J; Haase, Volker H.

Kidney Int ; 90(5): 1115-1122, 2016 11.

Artigo em Inglês | MEDLINE | ID: mdl-27650732

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Lipid kinase PIK3C3 maintains healthy brown and white adipose tissues to prevent metabolic diseases.

Deregulating iron-erythropoiesis regulation: transferrin receptor 2 as potential target for treating anemia in CKD.

Novel anemia therapies in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Epidermal sensing of oxygen is essential for systemic hypoxic response.

Inhibition of hypoxia-inducible factor-prolyl hydroxylation protects from cyclophosphamide-induced bladder injury and urinary dysfunction.

The ins and outs of ferric citrate.

Disruption of mitochondrial complex III in cap mesenchyme but not in ureteric progenitors results in defective nephrogenesis associated with amino acid deficiency.

Erythropoietic effects of vadadustat in patients with anemia associated with chronic kidney disease.

Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system.

Hypoxia-inducible factors in CD4⁺ T cells promote metabolism, switch cytokine secretion, and T cell help in humoral immunity.

Stabilization of hypoxia-inducible factor ameliorates glomerular injury sensitization after tubulointerstitial injury.

Controversies in optimal anemia management: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference.

Kidney epithelial targeted mitochondrial transcription factor A deficiency results in progressive mitochondrial depletion associated with severe cystic disease.

Got glycogen? An energy resource in HIF-mediated prevention of ischemic kidney injury.

Effects of vadadustat on hemoglobin concentrations in patients receiving hemodialysis previously treated with erythropoiesis-stimulating agents.

Prolyl-4-hydroxylase 2 and 3 coregulate murine erythropoietin in brain pericytes.

Therapeutic targeting of the HIF oxygen-sensing pathway: Lessons learned from clinical studies.

Hypoxia-inducible factor prolyl-4-hydroxylation in FOXD1 lineage cells is essential for normal kidney development.

Endothelial HIF signaling regulates pulmonary fibrosis-associated pulmonary hypertension.

Vadadustat, a novel oral HIF stabilizer, provides effective anemia treatment in nondialysis-dependent chronic kidney disease.