Detalhe da pesquisa
1.
Targeting Plasmodium PI(4)K to eliminate malaria.
Nature
; 504(7479): 248-253, 2013 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24284631
2.
Discovery of novel pyrrolidineoxy-substituted heteroaromatics as potent and selective PI3K delta inhibitors with improved physicochemical properties.
Bioorg Med Chem Lett
; 26(23): 5657-5662, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27816514
3.
Identification and optimisation of a 4',5-bisthiazole series of selective phosphatidylinositol-3 kinase alpha inhibitors.
Bioorg Med Chem Lett
; 25(17): 3569-74, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26206504
4.
A High-Throughput Screening Identifies MICU1 Targeting Compounds.
Cell Rep
; 30(7): 2321-2331.e6, 2020 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32075766
5.
Different species of alpha-synuclein oligomers induce calcium influx and seeding.
J Neurosci
; 27(34): 9220-32, 2007 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-17715357
6.
Pharmacological profiling of chemokine receptor-directed compounds using high-content screening.
J Biomol Screen
; 13(1): 40-53, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18227225
7.
How Phenotypic Screening Influenced Drug Discovery: Lessons from Five Years of Practice.
Assay Drug Dev Technol
; 15(6): 239-246, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28800248
8.
G protein-coupled receptor internalization assays in the high-content screening format.
Methods Enzymol
; 414: 121-39, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-17110190
9.
Comparison of G-protein coupled receptor desensitization-related beta-arrestin redistribution using confocal and non-confocal imaging.
Comb Chem High Throughput Screen
; 9(1): 37-47, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16454685
10.
Automated high content screening for phosphoinositide 3 kinase inhibition using an AKT 1 redistribution assay.
Comb Chem High Throughput Screen
; 9(5): 339-50, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16787147
11.
Characterization of kinase inhibitors using reverse phase protein arrays.
Methods Mol Biol
; 785: 79-107, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21901595
12.
A drug resistance screen using a selective MET inhibitor reveals a spectrum of mutations that partially overlap with activating mutations found in cancer patients.
Cancer Res
; 71(15): 5255-64, 2011 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21697284
13.
High content screening of CXCR2-dependent signalling pathways.
Comb Chem High Throughput Screen
; 13(1): 3-15, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20214572
14.
Arabidopsis transportin1 is the nuclear import receptor for the circadian clock-regulated RNA-binding protein AtGRP7.
Plant Mol Biol
; 53(1-2): 201-12, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-14756317