Detalhe da pesquisa
1.
Diet-induced obesity worsens allergen-induced type 2/type 17 inflammation in airways by enhancing DUOX1 activation.
Am J Physiol Lung Cell Mol Physiol
; 324(2): L228-L242, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36625485
2.
Oxidation-Dependent Activation of Src Kinase Mediates Epithelial IL-33 Production and Signaling during Acute Airway Allergen Challenge.
J Immunol
; 206(12): 2989-2999, 2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34088769
3.
Profibrotic epithelial TGF-ß1 signaling involves NOX4-mitochondria cross talk and redox-mediated activation of the tyrosine kinase FYN.
Am J Physiol Lung Cell Mol Physiol
; 320(3): L356-L367, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33325804
4.
Downregulation of DUOX1 function contributes to aging-related impairment of innate airway injury responses and accelerated senile emphysema.
Am J Physiol Lung Cell Mol Physiol
; 321(1): L144-L158, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33951398
5.
The Transient Receptor Potential Channel Vanilloid 1 Is Critical in Innate Airway Epithelial Responses to Protease Allergens.
Am J Respir Cell Mol Biol
; 63(2): 198-208, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32182090
6.
The NADPH Oxidases DUOX1 and NOX2 Play Distinct Roles in Redox Regulation of Epidermal Growth Factor Receptor Signaling.
J Biol Chem
; 291(44): 23282-23293, 2016 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27650496
7.
Airway epithelial dual oxidase 1 mediates allergen-induced IL-33 secretion and activation of type 2 immune responses.
J Allergy Clin Immunol
; 137(5): 1545-1556.e11, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26597162
8.
Acrolein and thiol-reactive electrophiles suppress allergen-induced innate airway epithelial responses by inhibition of DUOX1 and EGFR.
Am J Physiol Lung Cell Mol Physiol
; 311(5): L913-L923, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27612966
9.
Identification of tyrosine brominated extracellular matrix proteins in normal and fibrotic lung tissues.
Redox Biol
; 71: 103102, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38430684
10.
Dual oxidase-1 is required for airway epithelial cell migration and bronchiolar reepithelialization after injury.
Am J Respir Cell Mol Biol
; 48(3): 337-45, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23239498
11.
Acrolein exposure suppresses antigen-induced pulmonary inflammation.
Respir Res
; 14: 107, 2013 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24131734
12.
Macrophage-intrinsic DUOX1 contributes to type 2 inflammation and mucus metaplasia during allergic airway disease.
Mucosal Immunol
; 15(5): 977-989, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35654836
13.
Downregulation of epithelial DUOX1 in chronic obstructive pulmonary disease.
JCI Insight
; 6(2)2021 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33301419
14.
Dysregulated Redox Regulation Contributes to Nuclear EGFR Localization and Pathogenicity in Lung Cancer.
Sci Rep
; 9(1): 4844, 2019 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30890751
15.
Regulation of pancreatic beta-cell regeneration in the normoglycemic 60% partial-pancreatectomy mouse.
Diabetes
; 55(12): 3289-98, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17130472
16.
Mechanisms of compensatory beta-cell growth in insulin-resistant rats: roles of Akt kinase.
Diabetes
; 54(8): 2294-304, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16046294
17.
Inhalation of the reactive aldehyde acrolein promotes antigen sensitization to ovalbumin and enhances neutrophilic inflammation.
J Immunotoxicol
; 13(2): 191-7, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-25875327
18.
DUOX1 mediates persistent epithelial EGFR activation, mucous cell metaplasia, and airway remodeling during allergic asthma.
JCI Insight
; 1(18): e88811, 2016 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27812543
19.
Identification of DUOX1-dependent redox signaling through protein S-glutathionylation in airway epithelial cells.
Redox Biol
; 2: 436-46, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24624333
20.
Sexually dimorphic diet-induced insulin resistance in obese tissue inhibitor of metalloproteinase-2 (TIMP-2)-deficient mice.
Endocrinology
; 152(4): 1300-13, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21285317