Detalhe da pesquisa
1.
Autofluorescent Artemisinin-Benzimidazole Hybrids via Organo-Click Reaction: Study of Antiviral Properties and Mode of Action in Living Cells.
Chemistry
; 29(48): e202301194, 2023 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37267160
2.
Anti-SARS-CoV-2 Inhibitory Profile of New Quinoline Compounds in Cell Culture-Based Infection Models.
Chemistry
; 28(4): e202200039, 2022 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35043485
3.
Anti-SARS-CoV-2 Inhibitory Profile of New Quinoline Compounds in Cell Culture-Based Infection Models.
Chemistry
; 28(4): e202103861, 2022 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34859926
4.
Cyclin-Dependent Kinases (CDKs) and the Human Cytomegalovirus-Encoded CDK Ortholog pUL97 Represent Highly Attractive Targets for Synergistic Drug Combinations.
Int J Mol Sci
; 23(5)2022 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35269635
5.
Combinatorial Drug Treatments Reveal Promising Anticytomegaloviral Profiles for Clinically Relevant Pharmaceutical Kinase Inhibitors (PKIs).
Int J Mol Sci
; 22(2)2021 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33430060
6.
Development of a PROTAC-Based Targeting Strategy Provides a Mechanistically Unique Mode of Anti-Cytomegalovirus Activity.
Int J Mol Sci
; 22(23)2021 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34884662
7.
Cyclins B1, T1, and H differ in their molecular mode of interaction with cytomegalovirus protein kinase pUL97.
J Biol Chem
; 294(15): 6188-6203, 2019 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30782840
8.
(Iso)Quinoline-Artemisinin Hybrids Prepared through Click Chemistry: Highly Potent Agents against Viruses.
Chemistry
; 26(52): 12019-12026, 2020 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32485071
9.
The Artemisinin-Derived Autofluorescent Compound BG95 Exerts Strong Anticytomegaloviral Activity Based on a Mitochondrial Targeting Mechanism.
Int J Mol Sci
; 21(15)2020 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32759737
10.
Visible-Light-Driven C-H Oxidation of Cyclic Tertiary Amines: Access to Synthetic Strychnos Alkaloids with Antiviral Activity.
Chemistry
; 25(16): 4062-4066, 2019 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30620121
11.
Synthesis of new betulinic acid/betulin-derived dimers and hybrids with potent antimalarial and antiviral activities.
Bioorg Med Chem
; 27(1): 110-115, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30503412
12.
Synthesis of Artemisinin-Derived Dimers, Trimers and Dendrimers: Investigation of Their Antimalarial and Antiviral Activities Including Putative Mechanisms of Action.
Chemistry
; 24(32): 8103-8113, 2018 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29570874
13.
Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin.
Bioorg Med Chem
; 26(12): 3610-3618, 2018 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29887512
14.
HIV-1 p6 - a structured to flexible multifunctional membrane-interacting protein.
Biochim Biophys Acta
; 1828(2): 816-23, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23174350
15.
Influenza A virus protein PB1-F2 from different strains shows distinct structural signatures.
Biochim Biophys Acta
; 1834(2): 568-82, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23220419
16.
Preliminary study on carprofen concentration measurements after transcutaneous treatment with Vetdrop® in a microfracture joint defect model in sheep.
BMC Vet Res
; 10: 268, 2014 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25488522
17.
Validation of nuclear receptor RORγ isoform 1 as a novel host-directed antiviral target based on the modulation of cholesterol levels.
Antiviral Res
; 221: 105769, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38056603
18.
An Antiherpesviral Host-Directed Strategy Based on CDK7 Covalently Binding Drugs: Target-Selective, Picomolar-Dose, Cross-Virus Reactivity.
Pharmaceutics
; 16(2)2024 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38399219
19.
Assessment of Covalently Binding Warhead Compounds in the Validation of the Cytomegalovirus Nuclear Egress Complex as an Antiviral Target.
Cells
; 12(8)2023 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37190072
20.
The Oligomeric Assemblies of Cytomegalovirus Core Nuclear Egress Proteins Are Associated with Host Kinases and Show Sensitivity to Antiviral Kinase Inhibitors.
Viruses
; 14(5)2022 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35632762