Pesquisa | BVS Violência e Saúde

1.

B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity.

Qian, Jason; Wang, Qiao; Dose, Marei; Pruett, Nathanael; Kieffer-Kwon, Kyong-Rim; Resch, Wolfgang; Liang, Genqing; Tang, Zhonghui; Mathé, Ewy; Benner, Christopher; Dubois, Wendy; Nelson, Steevenson; Vian, Laura; Oliveira, Thiago Y; Jankovic, Mila; Hakim, Ofir; Gazumyan, Anna; Pavri, Rushad; Awasthi, Parirokh; Song, Bin; Liu, Geng; Chen, Longyun; Zhu, Shida; Feigenbaum, Lionel; Staudt, Louis; Murre, Cornelis; Ruan, Yijun; Robbiani, Davide F; Pan-Hammarström, Qiang; Nussenzweig, Michel C; Casellas, Rafael.

Cell ; 159(7): 1524-37, 2014 Dec 18.

Artigo em Inglês | MEDLINE | ID: mdl-25483777

2.

Interactome maps of mouse gene regulatory domains reveal basic principles of transcriptional regulation.

Kieffer-Kwon, Kyong-Rim; Tang, Zhonghui; Mathe, Ewy; Qian, Jason; Sung, Myong-Hee; Li, Guoliang; Resch, Wolfgang; Baek, Songjoon; Pruett, Nathanael; Grøntved, Lars; Vian, Laura; Nelson, Steevenson; Zare, Hossein; Hakim, Ofir; Reyon, Deepak; Yamane, Arito; Nakahashi, Hirotaka; Kovalchuk, Alexander L; Zou, Jizhong; Joung, J Keith; Sartorelli, Vittorio; Wei, Chia-Lin; Ruan, Xiaoan; Hager, Gordon L; Ruan, Yijun; Casellas, Rafael.

Cell ; 155(7): 1507-20, 2013 Dec 19.

Artigo em Inglês | MEDLINE | ID: mdl-24360274

3.

Ep300 sequestration to functionally distinct glucocorticoid receptor binding loci underlie rapid gene activation and repression.

Portuguez, Avital Sarusi; Grbesa, Ivana; Tal, Moran; Deitch, Rachel; Raz, Dana; Kliker, Limor; Weismann, Ran; Schwartz, Michal; Loza, Olga; Cohen, Leslie; Marchenkov-Flam, Libi; Sung, Myong-Hee; Kaplan, Tommy; Hakim, Ofir.

Nucleic Acids Res ; 50(12): 6702-6714, 2022 07 08.

Artigo em Inglês | MEDLINE | ID: mdl-35713523

4.

Dose-Dependent Transcriptional Response to Ionizing Radiation Is Orchestrated with DNA Repair within the Nuclear Space.

Chaturvedi, Garima; Sarusi-Portuguez, Avital; Loza, Olga; Shimoni-Sebag, Ariel; Yoron, Orly; Lawrence, Yaacov Richard; Zach, Leor; Hakim, Ofir.

Int J Mol Sci ; 25(2)2024 Jan 12.

Artigo em Inglês | MEDLINE | ID: mdl-38256047

5.

SnapShot: Chromosome confirmation capture.

Hakim, Ofir; Misteli, Tom.

Cell ; 148(5): 1068.e1-2, 2012 Mar 02.

Artigo em Inglês | MEDLINE | ID: mdl-22385969

6.

Chromatin dynamics enable transcriptional rhythms in the cnidarian Nematostella vectensis.

Weizman, Eviatar N; Tannenbaum, Miriam; Tarrant, Ann M; Hakim, Ofir; Levy, Oren.

PLoS Genet ; 15(11): e1008397, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-31693674

7.

Early Th1 cell differentiation is marked by a Tfh cell-like transition.

Nakayamada, Shingo; Kanno, Yuka; Takahashi, Hayato; Jankovic, Dragana; Lu, Kristina T; Johnson, Thomas A; Sun, Hong-wei; Vahedi, Golnaz; Hakim, Ofir; Handon, Robin; Schwartzberg, Pamela L; Hager, Gordon L; O'Shea, John J.

Immunity ; 35(6): 919-31, 2011 Dec 23.

Artigo em Inglês | MEDLINE | ID: mdl-22195747

8.

The Position and Complex Genomic Architecture of Plant T-DNA Insertions Revealed by 4SEE.

Krispil, Ronen; Tannenbaum, Miriam; Sarusi-Portuguez, Avital; Loza, Olga; Raskina, Olga; Hakim, Ofir.

Int J Mol Sci ; 21(7)2020 Mar 30.

Artigo em Inglês | MEDLINE | ID: mdl-32235482

9.

Dynamics of chromatin accessibility and long-range interactions in response to glucocorticoid pulsing.

Stavreva, Diana A; Coulon, Antoine; Baek, Songjoon; Sung, Myong-Hee; John, Sam; Stixova, Lenka; Tesikova, Martina; Hakim, Ofir; Miranda, Tina; Hawkins, Mary; Stamatoyannopoulos, John A; Chow, Carson C; Hager, Gordon L.

Genome Res ; 25(6): 845-57, 2015 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-25677181

10.

DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes.

Hakim, Ofir; Resch, Wolfgang; Yamane, Arito; Klein, Isaac; Kieffer-Kwon, Kyong-Rim; Jankovic, Mila; Oliveira, Thiago; Bothmer, Anne; Voss, Ty C; Ansarah-Sobrinho, Camilo; Mathe, Ewy; Liang, Genqing; Cobell, Jesse; Nakahashi, Hirotaka; Robbiani, Davide F; Nussenzweig, Andre; Hager, Gordon L; Nussenzweig, Michel C; Casellas, Rafael.

Nature ; 484(7392): 69-74, 2012 Feb 07.

Artigo em Inglês | MEDLINE | ID: mdl-22314321

11.

Epigenetic targeting of activation-induced cytidine deaminase.

Wang, Qiao; Oliveira, Thiago; Jankovic, Mila; Silva, Israel T; Hakim, Ofir; Yao, Kaihui; Gazumyan, Anna; Mayer, Christian T; Pavri, Rushad; Casellas, Rafael; Nussenzweig, Michel C; Robbiani, Davide F.

Proc Natl Acad Sci U S A ; 111(52): 18667-72, 2014 Dec 30.

Artigo em Inglês | MEDLINE | ID: mdl-25512519

12.

Spatial congregation of STAT binding directs selective nuclear architecture during T-cell functional differentiation.

Hakim, Ofir; Sung, Myong-Hee; Nakayamada, Shingo; Voss, Ty C; Baek, Songjoon; Hager, Gordon L.

Genome Res ; 23(3): 462-72, 2013 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-23212947

13.

FIE, a nuclear PRC2 protein, forms cytoplasmic complexes in Arabidopsis thaliana.

Oliva, Moran; Butenko, Yana; Hsieh, Tzung-Fu; Hakim, Ofir; Katz, Aviva; Smorodinsky, Nechama I; Michaeli, Daphna; Fischer, Robert L; Ohad, Nir.

J Exp Bot ; 67(21): 6111-6123, 2016 11.

Artigo em Inglês | MEDLINE | ID: mdl-27811080

14.

The origin of B cell recurrent chromosomal translocations: proximity versus DNA damage.

Casellas, Rafael; Resch, Wolfgang; Hakim, Ofir; Nussenzweig, Michel C.

Mol Cell ; 51(3): 275-6, 2013 Aug 08.

Artigo em Inglês | MEDLINE | ID: mdl-23932709

15.

Mouse model of endemic Burkitt translocations reveals the long-range boundaries of Ig-mediated oncogene deregulation.

Kovalchuk, Alexander L; Ansarah-Sobrinho, Camilo; Hakim, Ofir; Resch, Wolfgang; Tolarová, Helena; Dubois, Wendy; Yamane, Arito; Takizawa, Makiko; Klein, Isaac; Hager, Gordon L; Morse, Herbert C; Potter, Michael; Nussenzweig, Michel C; Casellas, Rafael.

Proc Natl Acad Sci U S A ; 109(27): 10972-7, 2012 Jul 03.

Artigo em Inglês | MEDLINE | ID: mdl-22711821

16.

Diverse gene reprogramming events occur in the same spatial clusters of distal regulatory elements.

Hakim, Ofir; Sung, Myong-Hee; Voss, Ty C; Splinter, Erik; John, Sam; Sabo, Peter J; Thurman, Robert E; Stamatoyannopoulos, John A; de Laat, Wouter; Hager, Gordon L.

Genome Res ; 21(5): 697-706, 2011 May.

Artigo em Inglês | MEDLINE | ID: mdl-21471403

17.

Rapid DNA-FISH in Arabidopsis thaliana Somatic Cells.

Raskina, Olga; Hakim, Ofir.

Methods Mol Biol ; 2784: 259-270, 2024.

Artigo em Inglês | MEDLINE | ID: mdl-38502491

18.

Genomic retargeting of p53 and CTCF is associated with transcriptional changes during oncogenic HRas-induced transformation.

Schwartz, Michal; Portugez, Avital Sarusi; Attia, Bracha Zukerman; Tannenbaum, Miriam; Cohen, Leslie; Loza, Olga; Chase, Emily; Turman, Yousef; Kaplan, Tommy; Salah, Zaidoun; Hakim, Ofir.

Commun Biol ; 3(1): 696, 2020 11 25.

Artigo em Inglês | MEDLINE | ID: mdl-33239721

19.

Regulatory chromatin landscape in Arabidopsis thaliana roots uncovered by coupling INTACT and ATAC-seq.

Tannenbaum, Miriam; Sarusi-Portuguez, Avital; Krispil, Ronen; Schwartz, Michal; Loza, Olga; Benichou, Jennifer I C; Mosquna, Assaf; Hakim, Ofir.

Plant Methods ; 14: 113, 2018.

Artigo em Inglês | MEDLINE | ID: mdl-30598689

20.

Genomic effects of glucocorticoids.

Grbesa, Ivana; Hakim, Ofir.

Protoplasma ; 254(3): 1175-1185, 2017 May.

Artigo em Inglês | MEDLINE | ID: mdl-28013411

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