Detalhe da pesquisa
1.
BRD4-PRC2 represses transcription of T-helper 2-specific negative regulators during T-cell differentiation.
EMBO J
; 42(6): e111473, 2023 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36719036
2.
Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth.
Proc Natl Acad Sci U S A
; 115(31): 7949-7954, 2018 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30012592
3.
Discovery of new thienopyrimidine derivatives as potent and orally efficacious phosphoinositide 3-kinase inhibitors.
Bioorg Med Chem
; 26(3): 637-646, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29305298
4.
Synthesis and structure-activity relationships of PI3K/mTOR dual inhibitors from a series of 2-amino-4-methylpyrido[2,3-d]pyrimidine derivatives.
Bioorg Med Chem Lett
; 24(18): 4538-4541, 2014 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25139570
5.
Identification of novel 7-amino-5-methyl-1,6-naphthyridin-2(1H)-one derivatives as potent PI3K/mTOR dual inhibitors.
Bioorg Med Chem Lett
; 24(3): 790-3, 2014 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24433860
6.
Do the asymmetric effects of eco-digitalization amidst energy transition make or mar the strides toward environmental sustainability in the USA?
Environ Sci Pollut Res Int
; 30(59): 123412-123426, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37981613
7.
Discovery of thiadiazole amides as potent, S1P3-sparing agonists of sphingosine-1-phosphate 1 (S1P1) receptor.
Bioorg Med Chem Lett
; 22(7): 2456-9, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22386243
8.
Small Molecules with Big Promises for Curing Demyelinating Diseases.
Cell Chem Biol
; 26(4): 468-470, 2019 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31002801
9.
Studies on the metabolism of 4-methyl-piperazine-1-carbodithioc acid 3-cyano-3,3-diphenylpropyl ester hydrochloride in rats by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.
J Pharm Biomed Anal
; 44(5): 1127-32, 2007 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-17606352
10.
Discovery of a Novel Series of Thienopyrimidine as Highly Potent and Selective PI3K Inhibitors.
ACS Med Chem Lett
; 6(4): 434-8, 2015 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25893045
11.
Discovery of Biaryl Amides as Potent, Orally Bioavailable, and CNS Penetrant RORγt Inhibitors.
ACS Med Chem Lett
; 6(7): 787-92, 2015 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26191367
12.
Simultaneous determination of 4-methyl-piperazine-1-carbodithioc acid 3-cyano-3,3-diphenylpropyl ester hydrochloride and its major metabolite in rats by HPLC.
J Chromatogr Sci
; 48(2): 125-9, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20109290
13.
Analysis of 4-methyl-piperazine-1-carbodithioic acid 3-cyano-3,3-diphenyl-propyl ester hydrochloride and its major metabolites in rat plasma and tissues by LC-MS/MS.
J Sep Sci
; 30(13): 2080-5, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17638372
14.
Studies on the metabolism of 4-methylpiperazine-1-carbodithioc acid 3-cyano-3,3- diphenylpropyl ester hydrochloride in rat bile by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.
Rapid Commun Mass Spectrom
; 21(10): 1599-605, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17443489