Detalhe da pesquisa
1.
Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.
Proc Natl Acad Sci U S A
; 115(29): E6863-E6870, 2018 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29967165
2.
Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti-malaria Activity in Humanized Mice.
Angew Chem Int Ed Engl
; 60(17): 9279-9283, 2021 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33433953
3.
Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome InhibitorsâPart II.
J Med Chem
; 66(2): 1484-1508, 2023 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36630286
4.
Design, Synthesis, and Optimization of Macrocyclic Peptides as Species-Selective Antimalaria Proteasome Inhibitors.
J Med Chem
; 65(13): 9350-9375, 2022 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35727231
5.
The enzymatic activity of inositol hexakisphosphate kinase controls circulating phosphate in mammals.
Nat Commun
; 12(1): 4847, 2021 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34381031
6.
Macrocyclic Peptides that Selectively Inhibit the Mycobacterium tuberculosis Proteasome.
J Med Chem
; 64(9): 6262-6272, 2021 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33949190
7.
Selective Phenylimidazole-Based Inhibitors of the Mycobacterium tuberculosis Proteasome.
J Med Chem
; 62(20): 9246-9253, 2019 10 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31560200
8.
Novel Pure αVß3 Integrin Antagonists That Do Not Induce Receptor Extension, Prime the Receptor, or Enhance Angiogenesis at Low Concentrations.
ACS Pharmacol Transl Sci
; 2(6): 387-401, 2019 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32259072
9.
Discovery of 3,5-Diphenyl-4-methyl-1,3-oxazolidin-2-ones as Novel, Potent, and Orally Available Δ-5 Desaturase (D5D) Inhibitors.
J Med Chem
; 60(21): 8963-8981, 2017 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29023121
10.
Melanin-concentrating hormone receptor 1 antagonists. Synthesis and structure-activity relationships of novel 3-(aminomethyl)quinolines.
J Med Chem
; 55(5): 2353-66, 2012 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22309223