Detalhe da pesquisa
1.
A combinatorial approach for achieving CNS-selective RNAi.
Nucleic Acids Res
; 52(9): 5273-5284, 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38348876
2.
Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection.
Proc Natl Acad Sci U S A
; 120(11): e2219523120, 2023 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36893269
3.
Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease.
Mol Ther
; 31(6): 1661-1674, 2023 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37177784
4.
Cyclic di-GMP sensing histidine kinase PdtaS controls mycobacterial adaptation to carbon sources.
FASEB J
; 35(4): e21475, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33772870
5.
Docosanoic acid conjugation to siRNA enables functional and safe delivery to skeletal and cardiac muscles.
Mol Ther
; 29(4): 1382-1394, 2021 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33348054
6.
Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease.
Mol Ther
; 31(11): 3355-3356, 2023 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37751745
7.
Phosphatidylcholine head group chemistry alters the extrahepatic accumulation of lipid-conjugated siRNA.
Mol Ther Nucleic Acids
; 35(2): 102230, 2024 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38938759
8.
Antiplatelet Treatment Patterns and Outcomes for Secondary Stroke Prevention in the United Kingdom.
Cardiol Ther
; 12(4): 675-687, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37789237
9.
Challenges of Assessing Exon 53 Skipping of the Human DMD Transcript with Locked Nucleic Acid-Modified Antisense Oligonucleotides in a Mouse Model for Duchenne Muscular Dystrophy.
Nucleic Acid Ther
; 33(6): 348-360, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38010230
10.
Dendritic amphiphilic siRNA: Selective albumin binding, in vivo efficacy, and low toxicity.
Mol Ther Nucleic Acids
; 34: 102080, 2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38089931
11.
Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo.
Res Sq
; 2023 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37398145
12.
Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo.
bioRxiv
; 2023 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37292886
13.
Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin.
Nat Commun
; 14(1): 7099, 2023 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37925520
14.
Chemical optimization of siRNA for safe and efficient silencing of placental sFLT1.
Mol Ther Nucleic Acids
; 29: 135-149, 2022 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35847173