Pesquisa | BVS Violência e Saúde

1.

Cytokine-Mediated Degradation of the Transcription Factor ERG Impacts the Pulmonary Vascular Response to Systemic Inflammatory Challenge.

Schafer, Christopher M; Martin-Almedina, Silvia; Kurylowicz, Katarzyna; Dufton, Neil; Osuna-Almagro, Lourdes; Wu, Meng-Ling; Johnson, Charmain F; Shah, Aarti V; Haskard, Dorian O; Buxton, Andrianna; Willis, Erika; Wheeler, Kate; Turner, Sean; Chlebicz, Magdalena; Scott, Rizaldy P; Kovats, Susan; Cleuren, Audrey; Birdsey, Graeme M; Randi, Anna M; Griffin, Courtney T.

Arterioscler Thromb Vasc Biol ; 43(8): 1412-1428, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37317853

2.

Mortality risk prediction of high-sensitivity C-reactive protein in suspected acute coronary syndrome: A cohort study.

Kaura, Amit; Hartley, Adam; Panoulas, Vasileios; Glampson, Ben; Shah, Anoop S V; Davies, Jim; Mulla, Abdulrahim; Woods, Kerrie; Omigie, Joe; Shah, Anoop D; Thursz, Mark R; Elliott, Paul; Hemmingway, Harry; Williams, Bryan; Asselbergs, Folkert W; O'Sullivan, Michael; Lord, Graham M; Trickey, Adam; Sterne, Jonathan Ac; Haskard, Dorian O; Melikian, Narbeh; Francis, Darrel P; Koenig, Wolfgang; Shah, Ajay M; Kharbanda, Rajesh; Perera, Divaka; Patel, Riyaz S; Channon, Keith M; Mayet, Jamil; Khamis, Ramzi.

PLoS Med ; 19(2): e1003911, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-35192610

3.

Hematoma Resolution In Vivo Is Directed by Activating Transcription Factor 1.

Seneviratne, Anusha; Han, Yumeng; Wong, Eunice; Walter, Edward R H; Jiang, Lijun; Cave, Luke; Long, Nicholas J; Carling, David; Mason, Justin C; Haskard, Dorian O; Boyle, Joseph J.

Circ Res ; 127(7): 928-944, 2020 09 11.

Artigo em Inglês | MEDLINE | ID: mdl-32611235

4.

Comparing the clinical profile of adults and children with Behçet's syndrome in the UK.

Makmur, Eric L; Myers, Sam H; Hanns, Laura; Haskard, Dorian O; Brogan, Paul; Ambrose, Nicola.

Clin Exp Rheumatol ; 37 Suppl 121(6): 48-51, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31172922

5.

Natural IgM antibodies help fend off thrombosis.

Haskard, Dorian O.

Blood ; 137(10): 1280-1281, 2021 03 11.

Artigo em Inglês | MEDLINE | ID: mdl-33704393

6.

Zebrafish Model for Functional Screening of Flow-Responsive Genes.

Serbanovic-Canic, Jovana; de Luca, Amalia; Warboys, Christina; Ferreira, Pedro F; Luong, Le A; Hsiao, Sarah; Gauci, Ismael; Mahmoud, Marwa; Feng, Shuang; Souilhol, Celine; Bowden, Neil; Ashton, John-Paul; Walczak, Henning; Firmin, David; Krams, Rob; Mason, Justin C; Haskard, Dorian O; Sherwin, Spencer; Ridger, Victoria; Chico, Timothy J A; Evans, Paul C.

Arterioscler Thromb Vasc Biol ; 37(1): 130-143, 2017 01.

Artigo em Inglês | MEDLINE | ID: mdl-27834691

7.

Developing a Strategy for Interventional Molecular Imaging of Oxidized Low-Density Lipoprotein in Atherosclerosis.

Pandey, Samata S; Haskard, Dorian O; Khamis, Ramzi Y.

Mol Imaging ; 16: 1536012117723788, 2017.

Artigo em Inglês | MEDLINE | ID: mdl-28877655

8.

PARP-14 combines with tristetraprolin in the selective posttranscriptional control of macrophage tissue factor expression.

Iqbal, M Bilal; Johns, Michael; Cao, Jun; Liu, Yu; Yu, Sheng-Chun; Hyde, Gareth D; Laffan, Michael A; Marchese, Francesco P; Cho, Sung Hoon; Clark, Andrew R; Gavins, Felicity N; Woollard, Kevin J; Blackshear, Perry J; Mackman, Nigel; Dean, Jonathan L; Boothby, Mark; Haskard, Dorian O.

Blood ; 124(24): 3646-55, 2014 Dec 04.

Artigo em Inglês | MEDLINE | ID: mdl-25293769

9.

Synergistic therapeutic vascular cytoprotection against complement-mediated injury induced via a PKCα-, AMPK-, and CREB-dependent pathway.

Hamdulay, Shahir S; Wang, Bufei; Calay, Damien; Kiprianos, Allan P; Cole, Jennifer; Dumont, Odile; Dryden, Nicola; Randi, Anna M; Thornton, Clare C; Al-Rashed, Fahad; Hoong, Caroline; Shamsi, Aamir; Liu, Zilei; Holla, Vijay R; Boyle, Joseph J; Haskard, Dorian O; Mason, Justin C.

J Immunol ; 192(9): 4316-27, 2014 May 01.

Artigo em Inglês | MEDLINE | ID: mdl-24670799

10.

Cezanne regulates inflammatory responses to hypoxia in endothelial cells by targeting TRAF6 for deubiquitination.

Luong, Le A; Fragiadaki, Maria; Smith, Jennifer; Boyle, Joseph; Lutz, Jens; Dean, Jonathan L E; Harten, Sarah; Ashcroft, Margaret; Walmsley, Sarah R; Haskard, Dorian O; Maxwell, Patrick H; Walczak, Henning; Pusey, Charles; Evans, Paul C.

Circ Res ; 112(12): 1583-91, 2013 Jun 07.

Artigo em Inglês | MEDLINE | ID: mdl-23564640

11.

Disturbed flow promotes endothelial senescence via a p53-dependent pathway.

Warboys, Christina M; de Luca, Amalia; Amini, Narges; Luong, Le; Duckles, Hayley; Hsiao, Sarah; White, Alex; Biswas, Shukti; Khamis, Ramzi; Chong, Chuh K; Cheung, Wai-Mun; Sherwin, Spencer J; Bennett, Martin R; Gil, Jesus; Mason, Justin C; Haskard, Dorian O; Evans, Paul C.

Arterioscler Thromb Vasc Biol ; 34(5): 985-95, 2014 May.

Artigo em Inglês | MEDLINE | ID: mdl-24651677

12.

The transcription factor Erg regulates expression of histone deacetylase 6 and multiple pathways involved in endothelial cell migration and angiogenesis.

Birdsey, Graeme M; Dryden, Nicola H; Shah, Aarti V; Hannah, Rebecca; Hall, Matthew D; Haskard, Dorian O; Parsons, Maddy; Mason, Justin C; Zvelebil, Marketa; Gottgens, Berthold; Ridley, Anne J; Randi, Anna M.

Blood ; 119(3): 894-903, 2012 Jan 19.

Artigo em Inglês | MEDLINE | ID: mdl-22117042

13.

ICAM-2 regulates vascular permeability and N-cadherin localization through ezrin-radixin-moesin (ERM) proteins and Rac-1 signalling.

Amsellem, Valerie; Dryden, Nicola H; Martinelli, Roberta; Gavins, Felicity; Almagro, Lourdes Osuna; Birdsey, Graeme M; Haskard, Dorian O; Mason, Justin C; Turowski, Patric; Randi, Anna M.

Cell Commun Signal ; 12: 12, 2014 Mar 04.

Artigo em Inglês | MEDLINE | ID: mdl-24593809

14.

Activating transcription factor 1 directs Mhem atheroprotective macrophages through coordinated iron handling and foam cell protection.

Boyle, Joseph J; Johns, Michael; Kampfer, Theresa; Nguyen, Aivi T; Game, Laurence; Schaer, Dominik J; Mason, Justin C; Haskard, Dorian O.

Circ Res ; 110(1): 20-33, 2012 Jan 06.

Artigo em Inglês | MEDLINE | ID: mdl-22052915

15.

5'-AMP-activated protein kinase-activating transcription factor 1 cascade modulates human monocyte-derived macrophages to atheroprotective functions in response to heme or metformin.

Wan, Xinyi; Huo, Yilin; Johns, Michael; Piper, Emma; Mason, Justin C; Carling, David; Haskard, Dorian O; Boyle, Joseph J.

Arterioscler Thromb Vasc Biol ; 33(11): 2470-80, 2013 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-24051143

16.

Magnetic resonance imaging of vein wall thickness in patients with Behçet's syndrome.

Ambrose, Nicola; Pierce, Iain T; Gatehouse, Peter D; Haskard, Dorian O; Firmin, David N.

Clin Exp Rheumatol ; 32(4 Suppl 84): S99-102, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-25268665

17.

The transcription factor Erg controls endothelial cell quiescence by repressing activity of nuclear factor (NF)-κB p65.

Dryden, Nicola H; Sperone, Andrea; Martin-Almedina, Silvia; Hannah, Rebecca L; Birdsey, Graeme M; Khan, Samia Taufiq; Layhadi, Janice A; Mason, Justin C; Haskard, Dorian O; Göttgens, Berthold; Randi, Anna M.

J Biol Chem ; 287(15): 12331-42, 2012 Apr 06.

Artigo em Inglês | MEDLINE | ID: mdl-22337883

18.

Cytoprotective signaling and gene expression in endothelial cells and macrophages-lessons for atherosclerosis.

Haskard, Dorian O; Boyle, Joseph J; Evans, Paul C; Mason, Justin C; Randi, Anna M.

Microcirculation ; 20(3): 203-16, 2013 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-23121167

19.

Solid-phase immunoglobulins IgG and IgM activate macrophages with solid-phase IgM acting via a novel scavenger receptor a pathway.

Boyle, Joseph J; Christou, Ivy; Iqbal, M Bilal; Nguyen, Aivi T; Leung, Viola W Y; Evans, Paul C; Liu, Yu; Johns, Michael; Kirkham, Paul; Haskard, Dorian O.

Am J Pathol ; 181(1): 347-61, 2012 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-22658487

20.

Endothelial von Willebrand factor regulates angiogenesis.

Starke, Richard D; Ferraro, Francesco; Paschalaki, Koralia E; Dryden, Nicola H; McKinnon, Thomas A J; Sutton, Rachel E; Payne, Elspeth M; Haskard, Dorian O; Hughes, Alun D; Cutler, Daniel F; Laffan, Mike A; Randi, Anna M.

Blood ; 117(3): 1071-80, 2011 Jan 20.

Artigo em Inglês | MEDLINE | ID: mdl-21048155

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