Detalhe da pesquisa
1.
Chemical Specification of E3 Ubiquitin Ligase Engagement by Cysteine-Reactive Chemistry.
J Am Chem Soc
; 145(40): 21937-21944, 2023 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37767920
2.
Recent Advances in Chemical Biology Using Benzophenones and Diazirines as Radical Precursors.
Molecules
; 25(10)2020 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32414020
3.
Exploration of the Tunability of BRD4 Degradation by DCAF16 Trans-labelling Covalent Glues.
bioRxiv
; 2023 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37873358
4.
Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders.
bioRxiv
; 2023 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36824856
5.
Phenotypic Screening of Histone Deacetylase (HDAC) Inhibitors against Schistosoma mansoni.
ChemMedChem
; 17(18): e202100622, 2022 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35983937
6.
Discovery of HDAC6-Selective Inhibitor NN-390 with in Vitro Efficacy in Group 3 Medulloblastoma.
J Med Chem
; 65(4): 3193-3217, 2022 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35119267
7.
Unique Molecular Interaction with the Histone Deacetylase 6 Catalytic Tunnel: Crystallographic and Biological Characterization of a Model Chemotype.
J Med Chem
; 64(5): 2691-2704, 2021 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33576627
8.
Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia.
J Med Chem
; 64(12): 8486-8509, 2021 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34101461
9.
Characterization of Conformationally Constrained Benzanilide Scaffolds for Potent and Selective HDAC8 Targeting.
J Med Chem
; 63(15): 8634-8648, 2020 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32672458
10.
Crystal structures of the synthetic inter-mediate 3-[(6-chloro-7H-purin-7-yl)meth-yl]cyclo-butan-1-one, and of two oxetanocin derivatives: 3-[(6-chloro-8,9-di-hydro-7H-purin-7-yl)meth-yl]cyclo-butan-1-ol and 3-[(6-chloro-9H-purin-9-yl)meth-yl]cyclo-butan-1-ol.
Acta Crystallogr E Crystallogr Commun
; 75(Pt 6): 732-737, 2019 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31391955
11.
Synthesis of cyclobutane nucleoside analogues 3: Preparation of carbocyclic derivatives of oxetanocin.
Nucleosides Nucleotides Nucleic Acids
; 37(9): 518-531, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30188772