Detalhe da pesquisa
1.
Evaluation of Pyrazolyl-Indolizine Derivatives as Antimicrobial Agents: Synthesis, In vitro, In silico ADMET and Molecular Docking Studies.
Chem Biodivers
; : e202400825, 2024 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38802323
2.
Novel eco-friendly [1,2,4]triazolo[3,4-a]isoquinoline chalcone derivatives efficiency against fungal deterioration of ancient Egyptian mummy cartonnage, Egypt.
Arch Microbiol
; 205(2): 57, 2023 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36609727
3.
Novel Tetrahydro-[1,2,4]triazolo[3,4-a]isoquinoline Chalcones Suppress Breast Carcinoma through Cell Cycle Arrests and Apoptosis.
Molecules
; 28(8)2023 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37110575
4.
Anticancer activity of novel 3-(furan-2-yl)pyrazolyl and 3-(thiophen-2-yl)pyrazolyl hybrid chalcones: Synthesis and in vitro studies.
Arch Pharm (Weinheim)
; 355(3): e2100381, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-34939695
5.
Novel [l,2,4]triazolo[3,4-a]isoquinoline chalcones as new chemotherapeutic agents: Block IAP tyrosine kinase domain and induce both intrinsic and extrinsic pathways of apoptosis.
Invest New Drugs
; 39(1): 98-110, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32856275
6.
Newly Synthesized Arylazo Derivatives Induce Apoptosis and G2/M Cell Cycle Arrest With Molecular Docking Validation in Human Cancer Cell Lines.
Anticancer Agents Med Chem
; 23(10): 1192-1203, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36744691
7.
Theoretical and molecular mechanistic investigations of novel (3-(furan-2-yl)pyrazol-4-yl) chalcones against lung carcinoma cell line (A549).
Naunyn Schmiedebergs Arch Pharmacol
; 396(4): 719-736, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36469109
8.
[1,2,4] Triazolo [3,4-a]isoquinoline chalcone derivative exhibits anticancer activity via induction of oxidative stress, DNA damage, and apoptosis in Ehrlich solid carcinoma-bearing mice.
Naunyn Schmiedebergs Arch Pharmacol
; 395(10): 1225-1238, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35881165
9.
Synthesis, Cytotoxicity and Docking Simulation of Novel Annulated Dihydroisoquinoline Heterocycles.
Mini Rev Med Chem
; 20(12): 1166-1178, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32000650
10.
Molecular Docking Study, Cytotoxicity, Cell Cycle Arrest and Apoptotic Induction of Novel Chalcones Incorporating Thiadiazolyl Isoquinoline in Cervical Cancer.
Anticancer Agents Med Chem
; 20(1): 70-83, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31696811
11.
Synthesis, Cytotoxicity, Antimicrobial and Docking Simulation of Novel Pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[3,4-c] pyrimidine Derivatives.
Mini Rev Med Chem
; 19(8): 657-670, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30332953
12.
Biological Activity, Apoptotic Induction and Cell Cycle Arrest of New Hydrazonoyl Halides Derivatives.
Anticancer Agents Med Chem
; 19(9): 1141-1149, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30843494
13.
Synthesis and antimicrobial activity of some new pyrazole, fused pyrazolo[3,4-d]-pyrimidine and pyrazolo[4,3-e][1,2,4]-triazolo[1,5-c]pyrimidine derivatives.
Molecules
; 13(7): 1501-17, 2008 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-18719521
14.
Synthesis and biological activity of some new pyrazoline and pyrrolo[3,4-c]pyrazole-4,6-dione derivatives: reaction of nitrilimines with some dipolarophiles.
Molecules
; 13(4): 1011-24, 2008 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-18463603
15.
Cytotoxicity, molecular modeling, cell cycle arrest, and apoptotic induction induced by novel tetrahydro-[1,2,4]triazolo[3,4-a]isoquinoline chalcones.
Eur J Med Chem
; 143: 532-541, 2018 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29207336
16.
2-(4-Chlorophenyl)-1,3-dicyano-6,7-dihydro-4-imino-9,10-dimethoxybenzo[a]quinolizine-water (2/5).
Acta Crystallogr C
; 58(Pt 2): o122-4, 2002 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-11828129