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1.
Contemp Nurse ; 31(1): 57-70, 2008 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19117501

RESUMO

Knowledge of the experience of parenthood is usually from a woman's perspective. The resulting outcome is that knowledge about the experience of fatherhood has been limited. Fathers are starting to change this situation by sharing their experience as is evidenced by the overall response of 267 fathers to this study. This paper focuses on the exploration of 22 men's feelings and beliefs about fatherhood; and their expectations and views about parenting. The paper will also investigate how fathers' antenatal expectations matched the reality of early family life including emotional well-being, attitudes to parenting, adjustment to family life and sources of support. The quantitative and qualitative data of the 22 fathers who responded to both the antenatal and postnatal questionnaires used within this paper are drawn from a larger Queensland survey of women and men during the antenatal and postnatal period.


Assuntos
Adaptação Psicológica , Atitude Frente a Saúde , Pai , Acontecimentos que Mudam a Vida , Poder Familiar , Apoio Social , Adulto , Pai/educação , Pai/psicologia , Necessidades e Demandas de Serviços de Saúde , Humanos , Cuidado do Lactente/psicologia , Recém-Nascido , Masculino , Pessoa de Meia-Idade , Papel do Profissional de Enfermagem/psicologia , Pesquisa Metodológica em Enfermagem , Poder Familiar/psicologia , Comportamento Paterno , Cuidado Pós-Natal/psicologia , Cuidado Pré-Natal , Pesquisa Qualitativa , Queensland , Estresse Psicológico/etiologia , Estresse Psicológico/psicologia , Inquéritos e Questionários , Adulto Jovem
2.
Am J Med Genet B Neuropsychiatr Genet ; 131B(1): 10-5, 2004 Nov 15.
Artigo em Inglês | MEDLINE | ID: mdl-15384085

RESUMO

Markers near the NOTCH4 locus on chromosome 6p21.3 have been reported to be associated with schizophrenia in some studies. Since schizophrenia and bipolar affective disorder (BPAD) may share genetic determinants, we tested markers in and near NOTCH4 in a sample of 153 parent-offspring triads ascertained through a sibling pair with BPAD for evidence of association. This sample would have 80% power to detect an association at or above a genotype relative risk of 2.4 at the 10(-7) level of significance. In addition to the two markers previously showing the most significant association with schizophrenia, three additional nearby markers were studied. The five markers were genotyped using validated methods. Both single-marker and 3-marker haplotype data was analyzed using family-based association methods. No genome-wide significant association was detected between any of the five SNP-markers and BPAD in this sample. One marker showed nominal evidence of association (P = 0.049), but this evidence was not supported by haplotype analyses including nearby flanking markers or by case-control analysis using 93 Caucasian controls. These results do not support an association between genetic variation near NOTCH4 and BPAD in this sample.


Assuntos
Transtorno Bipolar/genética , Marcadores Genéticos/genética , Proteínas Proto-Oncogênicas/genética , Receptores de Superfície Celular/genética , Alelos , DNA/química , DNA/genética , Análise Mutacional de DNA , Feminino , Frequência do Gene , Variação Genética , Genótipo , Haplótipos/genética , Humanos , Desequilíbrio de Ligação , Masculino , Mutação , Polimorfismo de Nucleotídeo Único/genética , Receptor Notch4 , Receptores Notch , Repetições de Trinucleotídeos/genética
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