Detalhe da pesquisa
1.
Imbalance of the renin-angiotensin system may contribute to inflammation and fibrosis in IBD: a novel therapeutic target?
Gut
; 69(5): 841-851, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31409604
2.
Colonic myofibroblast cell line stimulates colonoid formation.
Am J Physiol Gastrointest Liver Physiol
; 306(7): G547-56, 2014 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24481605
3.
Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells.
Cancer Discov
; 14(2): 362-379, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37877779
4.
Unified framework for patient-derived, tumor-organoid-based predictive testing of standard-of-care therapies in metastatic colorectal cancer.
Cell Rep Med
; 4(12): 101335, 2023 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38118423
5.
Low-viscosity Matrix Suspension Culture for Human Colorectal Epithelial Organoids and Tumoroids.
Bio Protoc
; 12(8): e4394, 2022 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35800090
6.
Low-viscosity matrix suspension culture enables scalable analysis of patient-derived organoids and tumoroids from the large intestine.
Commun Biol
; 4(1): 1067, 2021 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34518628
7.
Defining the susceptibility of colorectal cancers to BH3-mimetic compounds.
Cell Death Dis
; 11(9): 735, 2020 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32913182
8.
Loss of Bcl-G, a Bcl-2 family member, augments the development of inflammation-associated colorectal cancer.
Cell Death Differ
; 27(2): 742-757, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31296963
9.
Colon organoid formation and cryptogenesis are stimulated by growth factors secreted from myofibroblasts.
PLoS One
; 13(6): e0199412, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29928021
10.
Signal therapy of human pancreatic cancer and NF1-deficient breast cancer xenograft in mice by a combination of PP1 and GL-2003, anti-PAK1 drugs (Tyr-kinase inhibitors).
Cancer Lett
; 245(1-2): 242-51, 2007 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-16540233
11.
Sichuan pepper extracts block the PAK1/cyclin D1 pathway and the growth of NF1-deficient cancer xenograft in mice.
Cancer Biol Ther
; 5(3): 305-9, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16418572
12.
Transplantable programmed death ligand 1 expressing gastroids from gastric cancer prone Nfkb1-/- mice.
Cell Death Dis
; 12(12): 1091, 2021 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34789734
13.
Signal therapy of breast cancers by the HDAC inhibitor FK228 that blocks the activation of PAK1 and abrogates the tamoxifen-resistance.
Cancer Biol Ther
; 4(9): 956-60, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16082189
14.
Signal therapy of NF1-deficient tumor xenograft in mice by the anti-PAK1 drug FK228.
Cancer Biol Ther
; 4(4): 379-81, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15846074
15.
PAK is essential for RAS-induced upregulation of cyclin D1 during the G1 to S transition.
Cell Cycle
; 3(1): 71-4, 2004 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-14657670
16.
Analysis of Wnt signalling dynamics during colon crypt development in 3D culture.
Sci Rep
; 5: 11036, 2015 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26087250
17.
A hypermorphic epithelial ß-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations.
Dis Model Mech
; 8(11): 1361-73, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26398937
18.
The Tyr-kinase inhibitor AG879, that blocks the ETK-PAK1 interaction, suppresses the RAS-induced PAK1 activation and malignant transformation.
Cancer Biol Ther
; 3(1): 96-101, 2004 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-14726663
19.
Synthesis and conformational analysis of a non-amidine factor Xa inhibitor that incorporates 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine as S4 binding element.
J Med Chem
; 47(21): 5167-82, 2004 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-15456260
20.
Analysis of Wnt signaling ß-catenin spatial dynamics in HEK293T cells.
BMC Syst Biol
; 8: 44, 2014 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24712863