Detalhe da pesquisa
1.
Direct evidence that the GPCR CysLTR2 mutant causative of uveal melanoma is constitutively active with highly biased signaling.
J Biol Chem
; 296: 100163, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33288675
2.
Generation of conditional oncogenic chromosomal translocations using CRISPR-Cas9 genomic editing and homology-directed repair.
J Pathol
; 242(1): 102-112, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28188619
3.
Combined Inhibition of Gαq and MEK Enhances Therapeutic Efficacy in Uveal Melanoma.
Clin Cancer Res
; 27(5): 1476-1490, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33229459
4.
GNA11 Q209L Mouse Model Reveals RasGRP3 as an Essential Signaling Node in Uveal Melanoma.
Cell Rep
; 22(9): 2455-2468, 2018 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29490280
5.
GNA11 Q209L Mouse Model Reveals RasGRP3 as an Essential Signaling Node in Uveal Melanoma.
Cell Rep
; 33(2): 108277, 2020 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33053353