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J Neurol Surg A Cent Eur Neurosurg ; 75(6): 447-52, 2014 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-24554611

RESUMO

BACKGROUND: Despite significant advances in the conservative management of pyogenic spondylodiscitis, consecutive instability, deformity, and/or neurologic compromise demands a prompt surgical intervention. However, in rare cases involving additional multilevel epidural abscess formation, the appropriate surgical strategy remains controversial. In this retrospective cohort analyses, we evaluated the efficacy of a single-stage posterior approach with the addition of a one-time multilevel epidural lavage via the surgically exposed interlaminar fenestration of the infected segment. METHODS: From January 2009 through December 2010, 73 patients presenting pyogenic spondylodiscitis with instability of the lumbar spine were admitted. In all cases, the surgical strategy included a radical resection of the affected intervertebral disc and stabilization by intervertebral fusion using a titanium cage with autologous bone grafting in a level-dependent posterior approach with additional pedicle screw-and-rod instrumentation. In cases where multilevel abscess formation was evident, the standard surgical procedure was complemented by drainage and irrigation of the abscess from posterior by carefully advancing a soft infant feeding tube via the surgically exposed epidural space under fluoroscopic guidance. All patients received complementary oral antibiotic therapy for 12 weeks and were followed-up for a minimum of 12 months postoperatively. RESULTS: Ten patients (three male and seven female patients; mean age: 64.9 ± 10.9 years) presented with an additional lumbar epidural abscess extending beyond three levels proximal or distal to the infected disc. In all 10 patients the laboratory-chemical inflammatory parameters (leukocyte count, C-reactive protein) remained within the physiologic range after completing antibiotic therapy throughout the 1-year follow-up period. The plain radiographs and magnetic resonance imaging demonstrated solid fusion and the complete remission of the initial abscess formation after 3 to 6 months with no recurrence of infection, respectively. CONCLUSION: The onetime epidural lavage presented in this small patient cohort proved to be an effective surgical adjunct with minimal exposure-related morbidity. We believe that the possibility of early mobilization and the patient's increased rehabilitation potential reduce the risk of nosocomial complications that often coincide with this multimorbid high-risk group of patients.


Assuntos
Discite/terapia , Abscesso Epidural/terapia , Fusão Vertebral/métodos , Irrigação Terapêutica/métodos , Idoso , Catéteres , Discite/microbiologia , Discite/cirurgia , Abscesso Epidural/microbiologia , Abscesso Epidural/cirurgia , Feminino , Humanos , Vértebras Lombares/microbiologia , Vértebras Lombares/patologia , Vértebras Lombares/cirurgia , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fusão Vertebral/instrumentação , Irrigação Terapêutica/instrumentação , Resultado do Tratamento
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