Detalhe da pesquisa
1.
Development of a high-content imaging assay for screening compound aggregation.
Anal Biochem
; 559: 30-33, 2018 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30142329
2.
An Fc domain protein-small molecule conjugate as an enhanced immunomodulator.
J Am Chem Soc
; 136(9): 3370-3, 2014 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24533830
3.
Component co-expression and purification of recombinant human pyruvate dehydrogenase complex from baculovirus infected SF9 cells.
Protein Expr Purif
; 97: 9-16, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24534072
4.
Site-specific introduction of an acetyl-lysine mimic into peptides and proteins by cysteine alkylation.
J Am Chem Soc
; 132(29): 9986-7, 2010 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20608637
5.
High-Throughput Cellular Thermal Shift Assays in Research and Drug Discovery.
SLAS Discov
; 25(2): 137-147, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31566060
6.
Protein tyrosine kinase-substrate interactions.
Curr Opin Struct Biol
; 16(6): 668-75, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17085043
7.
Modular Protein Ligation: A New Paradigm as a Reagent Platform for Pre-Clinical Drug Discovery.
Sci Rep
; 9(1): 13078, 2019 09 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31511536
8.
Structure and activity of enzymes that remove histone modifications.
Curr Opin Struct Biol
; 15(6): 673-80, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16263263
9.
A High-Throughput Dose-Response Cellular Thermal Shift Assay for Rapid Screening of Drug Target Engagement in Living Cells, Exemplified Using SMYD3 and IDO1.
SLAS Discov
; 23(1): 34-46, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28957646
10.
De novo discovery of serotonin N-acetyltransferase inhibitors.
J Med Chem
; 50(22): 5330-8, 2007 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17924613
11.
Structure of the Rtt109-AcCoA/Vps75 complex and implications for chaperone-mediated histone acetylation.
Structure
; 19(2): 221-31, 2011 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-21256037
12.
Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor.
Chem Biol
; 17(5): 471-82, 2010 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20534345
13.
Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP.
Nat Struct Mol Biol
; 15(7): 738-45, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18568037
14.
The human monocytic leukemia zinc finger histone acetyltransferase domain contains DNA-binding activity implicated in chromatin targeting.
J Biol Chem
; 282(50): 36603-13, 2007 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-17925393
15.
Acetylation of the p53 DNA-binding domain regulates apoptosis induction.
Mol Cell
; 24(6): 841-51, 2006 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-17189187