Detalhe da pesquisa
1.
Adjuvant Olaparib for Patients with BRCA1- or BRCA2-Mutated Breast Cancer.
N Engl J Med
; 384(25): 2394-2405, 2021 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34081848
2.
Patient-centric trials for therapeutic development in precision oncology.
Nature
; 526(7573): 361-70, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26469047
3.
Biomarker-driven phase 2 umbrella trial study for patients with recurrent small cell lung cancer failing platinum-based chemotherapy.
Cancer
; 126(17): 4002-4012, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32584426
4.
The impact of germline mutations on targeted therapy.
J Pathol
; 232(2): 230-43, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24114499
5.
Ceralasertib (AZD6738), an Oral ATR Kinase Inhibitor, in Combination with Carboplatin in Patients with Advanced Solid Tumors: A Phase I Study.
Clin Cancer Res
; 27(19): 5213-5224, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34301752
6.
Mechanisms of Acquired Resistance to Savolitinib, a Selective MET Inhibitor in MET-Amplified Gastric Cancer.
JCO Precis Oncol
; 42020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32923890
7.
Combination of Docetaxel Plus Savolitinib in Refractory Cancer Patients: A Report on Phase I Trial.
Transl Oncol
; 12(4): 597-601, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-30695737
8.
AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity.
Nat Commun
; 10(1): 5065, 2019 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31699977
9.
Tumor Genomic Profiling Guides Patients with Metastatic Gastric Cancer to Targeted Treatment: The VIKTORY Umbrella Trial.
Cancer Discov
; 9(10): 1388-1405, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31315834
10.
Neuromedin U stimulates contraction of human long saphenous vein and gastrointestinal smooth muscle in vitro.
Regul Pept
; 136(1-3): 109-16, 2006 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-16782214
11.
Defining actionable mutations for oncology therapeutic development.
Nat Rev Cancer
; 16(5): 319-29, 2016 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27112209
12.
Precision medicine in oncology drug development: a pharma perspective.
Drug Discov Today
; 20(12): 1455-63, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26482740
13.
The Challenges of Precision Oncology Drug Development and Implementation.
Public Health Genomics
; 18(6): 338-48, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26555355
14.
Use of a needleless injection system for digital ring block anesthesia.
J Am Podiatr Med Assoc
; 93(1): 23-6, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-12533552
15.
Advanced qRT-PCR technology allows detection of the cholecystokinin 1 receptor (CCK1R) expression in human pancreas.
Pancreas
; 31(4): 325-31, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16258365
16.
Expression of angiogenic VEGF-A (soluble isoforms 121, 165) and lymphangiogenic VEGF-C in colorectal cancers with micro-satellite instability.
J Surg Oncol
; 92(4): 317-25, 2005 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16299798