Detalhe da pesquisa
1.
A small-molecule activation mechanism that directly opens the KCNQ2 channel.
Nat Chem Biol
; 2024 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38167918
2.
CCDC50 promotes tumor growth through regulation of lysosome homeostasis.
EMBO Rep
; 24(10): e56948, 2023 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37672005
3.
Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers.
Proc Natl Acad Sci U S A
; 119(45): e2207067119, 2022 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36763058
4.
Reconstitution of RNA cap methylation reveals different features of SARS-CoV-2 and SARS-CoV methyltransferases.
J Med Virol
; 96(2): e29411, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38285434
5.
CCDC50 suppresses NLRP3 inflammasome activity by mediating autophagic degradation of NLRP3.
EMBO Rep
; 23(5): e54453, 2022 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35343634
6.
An unconventional role of an ASB family protein in NF-κB activation and inflammatory response during microbial infection and colitis.
Proc Natl Acad Sci U S A
; 118(3)2021 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33431678
7.
Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects.
Proc Natl Acad Sci U S A
; 118(20)2021 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33990467
8.
Chinese herbal medicine for the treatment of cardiovascular diseases â Targeting cardiac ion channels.
Pharmacol Res
; 192: 106765, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37075871
9.
Predicting Patient Response to the Antiarrhythmic Mexiletine Based on Genetic Variation.
Circ Res
; 124(4): 539-552, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30566038
10.
Purification of starch and phosphorus wastewater using core-shell magnetic seeds prepared by sulfated roasting.
J Environ Sci (China)
; 81: 4-16, 2019 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-30975328
11.
Regulation of the Alternative Splicing and Function of Cyclin T1 by the Serine-Arginine-Rich Protein ASF/SF2.
J Cell Biochem
; 118(11): 4020-4032, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28422315
12.
Genome modification of CXCR4 by Staphylococcus aureus Cas9 renders cells resistance to HIV-1 infection.
Retrovirology
; 14(1): 51, 2017 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29141633
13.
Structural basis for calcium and magnesium regulation of a large conductance calcium-activated potassium channel with ß1 subunits.
J Biol Chem
; 289(24): 16914-23, 2014 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24764303
14.
VHL negatively regulates SARS coronavirus replication by modulating nsp16 ubiquitination and stability.
Biochem Biophys Res Commun
; 459(2): 270-276, 2015 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25732088
15.
The regulation of NLRP3 inflammasome activation by CCDC50-mediated autophagy.
Autophagy
; 19(1): 365-366, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35620989
16.
Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun
; 14(1): 6632, 2023 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37857637
17.
A benzodiazepine activator locks Kv7.1 channels open by electro-mechanical uncoupling.
Commun Biol
; 5(1): 301, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35365746
18.
CDK4/6 Inhibition Enhances Oncolytic Virus Efficacy by Potentiating Tumor-Selective Cell Killing and T-cell Activation in Refractory Glioblastoma.
Cancer Res
; 82(18): 3359-3374, 2022 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35792620
19.
Autophagy receptor CCDC50 tunes the STING-mediated interferon response in viral infections and autoimmune diseases.
Cell Mol Immunol
; 18(10): 2358-2371, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34453126
20.
A novel selective autophagy receptor, CCDC50, delivers K63 polyubiquitination-activated RIG-I/MDA5 for degradation during viral infection.
Cell Res
; 31(1): 62-79, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32612200