Detalhe da pesquisa
1.
Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity
; 54(8): 1853-1868.e7, 2021 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34331873
2.
Kinetic characterization of an efficient cocaine hydrolase against toxic metabolites of cocaine.
Org Biomol Chem
; 21(17): 3650-3659, 2023 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37067022
3.
Drug Design Strategies to Avoid Resistance in Direct-Acting Antivirals and Beyond.
Chem Rev
; 121(6): 3238-3270, 2021 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33410674
4.
Structural basis of substrate specificity in human cytidine deaminase family APOBEC3s.
J Biol Chem
; 297(2): 100909, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34171358
5.
Cytotoxic Guaianolide Sesquiterpenoids from Ainsliaea fragrans.
J Nat Prod
; 84(9): 2568-2574, 2021 09 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34496568
6.
Precision 3D printed meniscus scaffolds to facilitate hMSCs proliferation and chondrogenic differentiation for tissue regeneration.
J Nanobiotechnology
; 19(1): 400, 2021 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34856996
7.
Mechanism for APOBEC3G catalytic exclusion of RNA and non-substrate DNA.
Nucleic Acids Res
; 47(14): 7676-7689, 2019 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31424549
8.
Computational Design and Crystal Structure of a Highly Efficient Benzoylecgonine Hydrolase.
Angew Chem Int Ed Engl
; 60(40): 21959-21965, 2021 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34351032
9.
Mutations in Influenza A Virus Neuraminidase and Hemagglutinin Confer Resistance against a Broadly Neutralizing Hemagglutinin Stem Antibody.
J Virol
; 93(2)2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30381484
10.
PEGylation but Not Fc-Fusion Improves in Vivo Residence Time of a Thermostable Mutant of Bacterial Cocaine Esterase.
Bioconjug Chem
; 30(12): 3021-3027, 2019 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31661952
11.
Long-acting cocaine hydrolase for addiction therapy.
Proc Natl Acad Sci U S A
; 113(2): 422-7, 2016 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26712009
12.
Plant expression of cocaine hydrolase-Fc fusion protein for treatment of cocaine abuse.
BMC Biotechnol
; 16(1): 72, 2016 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27756365
13.
Kinetic characterization of a cocaine hydrolase engineered from mouse butyrylcholinesterase.
Biochem J
; 466(2): 243-51, 2015 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25486543
14.
Kinetic characterization of high-activity mutants of human butyrylcholinesterase for the cocaine metabolite norcocaine.
Biochem J
; 457(1): 197-206, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24125115
15.
Kinetic characterization of human butyrylcholinesterase mutants for the hydrolysis of cocaethylene.
Biochem J
; 460(3): 447-57, 2014 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24870023
16.
Preparation and in vivo characterization of a cocaine hydrolase engineered from human butyrylcholinesterase for metabolizing cocaine.
Biochem J
; 453(3): 447-54, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23849058
17.
Substrate selectivity of high-activity mutants of human butyrylcholinesterase.
Org Biomol Chem
; 11(43): 7477-85, 2013 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24077614
18.
Human Butyrylcholinesterase Mutants for (-)-Cocaine Hydrolysis: A Correlation Relationship between Catalytic Efficiency and Total Hydrogen Bonding Energy with an Oxyanion Hole.
J Phys Chem B
; 127(50): 10723-10729, 2023 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38063500
19.
Synthesis-accessibility-oriented design of c-Jun N-terminal kinase 1 inhibitor.
Eur J Med Chem
; 256: 115442, 2023 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37156184
20.
Terragines F-G produced by endophytic Bacillus sp. SH-1.2-ROOT-18 from Dendrobium officinale.
Nat Prod Res
; 36(19): 5058-5063, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-33949250