Detalhe da pesquisa
1.
Mesenchyme-derived factors enhance preneoplastic growth by non-genotoxic carcinogens in rat liver.
Arch Toxicol
; 92(2): 953-966, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-29270806
2.
Use of HuH6 and other human-derived hepatoma lines for the detection of genotoxins: a new hope for laboratory animals?
Arch Toxicol
; 92(2): 921-934, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-29218508
3.
Proinflammatory mesenchymal effects of the non-genotoxic hepatocarcinogen phenobarbital: a novel mechanism of antiapoptosis and tumor promotion.
Carcinogenesis
; 36(12): 1521-30, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26378027
4.
Xanthohumol, a prenylated flavonoid contained in beer, prevents the induction of preneoplastic lesions and DNA damage in liver and colon induced by the heterocyclic aromatic amine amino-3-methyl-imidazo[4,5-f]quinoline (IQ).
Mutat Res
; 691(1-2): 17-22, 2010 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20547166
5.
Use of human derived liver cells for the detection of genotoxins in comet assays.
Mutat Res Genet Toxicol Environ Mutagen
; 845: 402995, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31561885
6.
Thiols and the chemoprevention of cancer.
Curr Opin Pharmacol
; 7(4): 404-9, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17644484
7.
Effects of coffee and its chemopreventive components kahweol and cafestol on cytochrome P450 and sulfotransferase in rat liver.
Food Chem Toxicol
; 46(4): 1230-8, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17983700
8.
Modification of N-acetyltransferases and glutathione S-transferases by coffee components: possible relevance for cancer risk.
Methods Enzymol
; 401: 307-41, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16399395
9.
Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepatic N-acetyltransferase and glutathione S-transferase activities.
Environ Mol Mutagen
; 44(4): 265-76, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15468054
10.
Coffee and its chemopreventive components Kahweol and Cafestol increase the activity of O6-methylguanine-DNA methyltransferase in rat liver--comparison with phase II xenobiotic metabolism.
Mutat Res
; 522(1-2): 57-68, 2003 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-12517412
11.
Protective effects of coffee against induction of DNA damage and pre-neoplastic foci by aflatoxin B1.
Mol Nutr Food Res
; 58(2): 229-38, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24039089
12.
Enhancement of glutathione and g-glutamylcysteine synthetase, the rate limiting enzyme of glutathione synthesis, by chemoprotective plant-derived food and beverage components in the human hepatoma cell line HepG2.
Nutr Cancer
; 45(1): 74-83, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-12791507
13.
Structurally related mycotoxins ochratoxin A, ochratoxin B, and citrinin differ in their genotoxic activities and in their mode of action in human-derived liver (HepG2) cells: implications for risk assessment.
Nutr Cancer
; 50(2): 190-7, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15623466
14.
Enhancement of the chemoprotective enzymes glucuronosyl transferase and glutathione transferase in specific organs of the rat by the coffee components kahweol and cafestol.
Arch Toxicol
; 76(4): 209-17, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12029384
15.
The coffee components kahweol and cafestol induce gamma-glutamylcysteine synthetase, the rate limiting enzyme of chemoprotective glutathione synthesis, in several organs of the rat.
Arch Toxicol
; 75(11-12): 685-94, 2002 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-11876501
16.
Prevention of heterocyclic amine-induced DNA damage in colon and liver of rats by different lactobacillus strains.
Carcinogenesis
; 24(12): 1913-8, 2003 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12970070