Detalhe da pesquisa
1.
Safety and efficacy of subcutaneous ianalumab (VAY736) in patients with primary Sjögren's syndrome: a randomised, double-blind, placebo-controlled, phase 2b dose-finding trial.
Lancet
; 399(10320): 161-171, 2022 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34861168
2.
Development and preliminary validation of the Sjögren's Tool for Assessing Response (STAR): a consensual composite score for assessing treatment effect in primary Sjögren's syndrome.
Ann Rheum Dis
; 81(7): 979-989, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35393271
3.
IL-17A inhibition by secukinumab induces early clinical, histopathologic, and molecular resolution of psoriasis.
J Allergy Clin Immunol
; 144(3): 750-763, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31129129
4.
Ianalumab in Sjögren's syndrome: what can we learn from lupus trials? - Authors' reply.
Lancet
; 400(10355): 808-809, 2022 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36088946
5.
Long-term effects of secukinumab on MRI findings in relation to clinical efficacy in subjects with active ankylosing spondylitis: an observational study.
Ann Rheum Dis
; 75(2): 408-12, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26248638
6.
Association of HLA-DRB1 alleles with clinical responses to the anti-interleukin-17A monoclonal antibody secukinumab in active rheumatoid arthritis.
Rheumatology (Oxford)
; 55(1): 49-55, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26268815
7.
Evidence that a neutrophil-keratinocyte crosstalk is an early target of IL-17A inhibition in psoriasis.
Exp Dermatol
; 24(7): 529-35, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25828362
8.
Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: a randomised, double-blind, placebo-controlled trial.
Lancet
; 382(9906): 1705-13, 2013 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24035250
9.
Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial.
Ann Rheum Dis
; 73(2): 349-56, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23361084
10.
Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial.
Gut
; 61(12): 1693-700, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22595313
11.
Development and testing of an alternative responder definition for EULAR Sjögren's Syndrome Patient Reported Index (ESSPRI).
RMD Open
; 9(1)2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36931685
12.
Autoimmunity against fibrinogen mediates inflammatory arthritis in mice.
J Immunol
; 184(1): 379-90, 2010 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19949094
13.
A broad screen for targets of immune complexes decorating arthritic joints highlights deposition of nucleosomes in rheumatoid arthritis.
Proc Natl Acad Sci U S A
; 106(37): 15867-72, 2009 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19720992
14.
Content Validity of Sjögren's Syndrome Symptom Diary and Functional Assessment of Chronic Illness Therapy-Fatigue in Patients with Sjögren's.
Rheumatol Ther
; 9(6): 1559-1574, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36152275
15.
Qualitative Research with Patients and Physicians to Assess Content Validity and Meaningful Change on ESSDAI and ESSPRI in Sjögren's.
Rheumatol Ther
; 9(6): 1499-1515, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36114443
16.
The number of elevated cytokines and chemokines in preclinical seropositive rheumatoid arthritis predicts time to diagnosis in an age-dependent manner.
Arthritis Rheum
; 62(11): 3161-72, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20597112
17.
Autoantigen microarrays for multiplex characterization of autoantibody responses.
Nat Med
; 8(3): 295-301, 2002 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-11875502
18.
Secukinumab for ankylosing spondylitis--authors' reply.
Lancet
; 383(9919): 780-1, 2014 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24581662
19.
Peptide-coated nanotube-based biosensor for the detection of disease-specific autoantibodies in human serum.
Biosens Bioelectron
; 23(10): 1413-21, 2008 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18222083
20.
Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis.
Sci Transl Med
; 2(52): 52ra72, 2010 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-20926833