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1.
J Neurophysiol ; 121(6): 2112-2125, 2019 06 01.
Artigo em Inglês | MEDLINE | ID: mdl-30943093

RESUMO

Previous studies have shown that cerebellar transcranial direct current stimulation (tDCS) leads to faster adaptation of arm reaching movements to visuomotor rotation and force field perturbations in healthy subjects. The first aim of the present study was to confirm a stimulation-dependent effect on motor adaptation. Second, we investigated whether tDCS effects differ depending on onset, that is, before or at the beginning of the adaptation phase. A total of 120 healthy and right-handed subjects (60 women, mean age 23.2 ± SD 2.7 yr, range 18-31 yr) were tested. Subjects moved a cursor with a manipulandum to one of eight targets presented on a vertically orientated screen. Three baseline blocks were followed by one adaptation block and three washout blocks. Sixty subjects did a force field adaptation task (FF), and 60 subjects did a visuomotor adaptation task (VM). Equal numbers of subjects received anodal, cathodal, or sham cerebellar tDCS beginning either in the third baseline block or at the start of the adaptation block. In FF and VM, tDCS and the onset of tDCS did not show a significant effect on motor adaptation (all P values >0.05). We were unable to support previous findings of modulatory cerebellar tDCS effects in reaching adaptation tasks in healthy subjects. Prior to possible application in patients with cerebellar disease, future experiments are needed to determine which tDCS and task parameters lead to robust tDCS effects. NEW & NOTEWORTHY Transcranial direct current stimulation (tDCS) is a promising tool to improve motor learning. We investigated whether cerebellar tDCS improves motor learning in force field and visuomotor tasks in healthy subjects and what influence the onset of stimulation has. We did not find stimulation effects of tDCS or an effect of onset of stimulation. A reevaluation of cerebellar tDCS in healthy subjects and at the end of the clinical potential in cerebellar patients is demanded.


Assuntos
Adaptação Fisiológica/fisiologia , Cerebelo/fisiologia , Aprendizagem/fisiologia , Atividade Motora/fisiologia , Desempenho Psicomotor/fisiologia , Estimulação Transcraniana por Corrente Contínua , Adolescente , Adulto , Feminino , Voluntários Saudáveis , Humanos , Masculino , Adulto Jovem
2.
J Am Podiatr Med Assoc ; 86(8): 396-8, 1996 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-8803412

RESUMO

While it is evident that poly-p-dioxanon is less reactive than polyglycolide, recent studies, including the case above, have shown that Orthosorb pins are not exempt from the same type of foreign-body reaction as the Biofix products.


Assuntos
Pinos Ortopédicos , Calo Ósseo/cirurgia , Reação a Corpo Estranho/etiologia , Polidioxanona/efeitos adversos , Complicações Pós-Operatórias , Adulto , Feminino , Humanos , Metatarso/cirurgia , Osteotomia , Suturas
3.
J Foot Ankle Surg ; 38(4): 283-9, 1999.
Artigo em Inglês | MEDLINE | ID: mdl-10464724

RESUMO

Dystonia is a movement disorder characterized by increased muscular tone for which surgical treatment has met with less than ideal results. Surgical treatment in patients with dystonia is often avoided due to the relative success of medical therapy. However, if expectations stay realistic and if the patient with dystonia is continuously evaluated, appropriate surgical measures may be taken when necessary to optimize patient satisfaction. The authors present a case of successful surgical treatment in a patient with a relatively static but crippling lower extremity deformity. A review of dystonia is included with successful surgical treatment of this compound neurologic disease causing lower extremity deformity in a young female. Diagnosis and treatment options including surgical planning and principles in the dystonic patient are highlighted.


Assuntos
Contratura/cirurgia , Distonia/cirurgia , Deformidades Adquiridas do Pé/cirurgia , Adulto , Contratura/etiologia , Distonia/classificação , Distonia/complicações , Distonia/terapia , Feminino , Seguimentos , , Deformidades Adquiridas do Pé/etiologia , Humanos , Transferência Tendinosa/métodos , Tendões/cirurgia
4.
J Foot Ankle Surg ; 37(6): 490-500, 1998.
Artigo em Inglês | MEDLINE | ID: mdl-9879044

RESUMO

This case series examines triple arthrodesis using articular cartilage excision without bone resection. Due to the technically demanding nature of triple arthrodesis, the authors present a nonresection technique with its perceived advantages over joint resection triple arthrodesis in the presence of reducible deformity, such as minimal shortening of bone, ease of execution, and better bony apposition. Fourteen patients with nonresection triple arthrodesis from two medical centers are included in this report. Postoperative follow-up ranged from 6 to 36 months. Evaluation of results was performed subjectively and radiographically. There was a low incidence of nonunion (2% of joints) and minimal to no bone shortening (0.1 cm mean talonavicular shortening and 0.1 cm mean increase in talocalcaneal height). Mean time to fusion of joints fixed with screws was 9.91 weeks (SD = 3.61, n = 31), while fusion time for staple or pin fixation was 8.96 weeks (SD = 4.15, n = 10). There were no significant differences in time to fusion between screw and nonscrew fixation (p = .26) nor when comparing procedures within each patient (p = .30). At follow-up, five patients reported no pain at any time (36%); two patients reported mild occasional pain (14%). Moderate, daily pain was reported by seven patients (50%). While no direct comparison with resection triple arthrodesis was made, the positive subjective and objective results support this procedure.


Assuntos
Artrodese/métodos , Cartilagem Articular/cirurgia , Deformidades do Pé/cirurgia , Articulações Tarsianas/cirurgia , Adolescente , Adulto , Idoso , Artrodese/efeitos adversos , Feminino , Deformidades do Pé/diagnóstico por imagem , Humanos , Masculino , Pessoa de Meia-Idade , Satisfação do Paciente , Radiografia , Estudos Retrospectivos , Terapia de Salvação , Articulações Tarsianas/diagnóstico por imagem
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