Pesquisa | BVS Violência e Saúde

1.

Molecular mechanisms of stress-induced reactivation in mumps virus condensates.

Zhang, Xiaojie; Sridharan, Sindhuja; Zagoriy, Ievgeniia; Eugster Oegema, Christina; Ching, Cyan; Pflaesterer, Tim; Fung, Herman K H; Becher, Isabelle; Poser, Ina; Müller, Christoph W; Hyman, Anthony A; Savitski, Mikhail M; Mahamid, Julia.

Cell ; 186(9): 1877-1894.e27, 2023 04 27.

Artigo em Inglês | MEDLINE | ID: mdl-37116470

2.

Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production.

Iserman, Christiane; Desroches Altamirano, Christine; Jegers, Ceciel; Friedrich, Ulrike; Zarin, Taraneh; Fritsch, Anatol W; Mittasch, Matthäus; Domingues, Antonio; Hersemann, Lena; Jahnel, Marcus; Richter, Doris; Guenther, Ulf-Peter; Hentze, Matthias W; Moses, Alan M; Hyman, Anthony A; Kramer, Günter; Kreysing, Moritz; Franzmann, Titus M; Alberti, Simon.

Cell ; 181(4): 818-831.e19, 2020 05 14.

Artigo em Inglês | MEDLINE | ID: mdl-32359423

3.

RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation.

Guillén-Boixet, Jordina; Kopach, Andrii; Holehouse, Alex S; Wittmann, Sina; Jahnel, Marcus; Schlüßler, Raimund; Kim, Kyoohyun; Trussina, Irmela R E A; Wang, Jie; Mateju, Daniel; Poser, Ina; Maharana, Shovamayee; Ruer-Gruß, Martine; Richter, Doris; Zhang, Xiaojie; Chang, Young-Tae; Guck, Jochen; Honigmann, Alf; Mahamid, Julia; Hyman, Anthony A; Pappu, Rohit V; Alberti, Simon; Franzmann, Titus M.

Cell ; 181(2): 346-361.e17, 2020 04 16.

Artigo em Inglês | MEDLINE | ID: mdl-32302572

4.

Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing.

Alberti, Simon; Hyman, Anthony A.

Nat Rev Mol Cell Biol ; 22(3): 196-213, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-33510441

5.

A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins.

Wang, Jie; Choi, Jeong-Mo; Holehouse, Alex S; Lee, Hyun O; Zhang, Xiaojie; Jahnel, Marcus; Maharana, Shovamayee; Lemaitre, Régis; Pozniakovsky, Andrei; Drechsel, David; Poser, Ina; Pappu, Rohit V; Alberti, Simon; Hyman, Anthony A.

Cell ; 174(3): 688-699.e16, 2018 07 26.

Artigo em Inglês | MEDLINE | ID: mdl-29961577

6.

The Centrosome Is a Selective Condensate that Nucleates Microtubules by Concentrating Tubulin.

Woodruff, Jeffrey B; Ferreira Gomes, Beatriz; Widlund, Per O; Mahamid, Julia; Honigmann, Alf; Hyman, Anthony A.

Cell ; 169(6): 1066-1077.e10, 2017 Jun 01.

Artigo em Inglês | MEDLINE | ID: mdl-28575670

7.

Amyloid-like Self-Assembly of a Cellular Compartment.

Boke, Elvan; Ruer, Martine; Wühr, Martin; Coughlin, Margaret; Lemaitre, Regis; Gygi, Steven P; Alberti, Simon; Drechsel, David; Hyman, Anthony A; Mitchison, Timothy J.

Cell ; 166(3): 637-650, 2016 Jul 28.

Artigo em Inglês | MEDLINE | ID: mdl-27471966

8.

Polar Positioning of Phase-Separated Liquid Compartments in Cells Regulated by an mRNA Competition Mechanism.

Saha, Shambaditya; Weber, Christoph A; Nousch, Marco; Adame-Arana, Omar; Hoege, Carsten; Hein, Marco Y; Osborne-Nishimura, Erin; Mahamid, Julia; Jahnel, Marcus; Jawerth, Louise; Pozniakovski, Andrej; Eckmann, Christian R; Jülicher, Frank; Hyman, Anthony A.

Cell ; 166(6): 1572-1584.e16, 2016 Sep 08.

Artigo em Inglês | MEDLINE | ID: mdl-27594427

9.

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.

Hein, Marco Y; Hubner, Nina C; Poser, Ina; Cox, Jürgen; Nagaraj, Nagarjuna; Toyoda, Yusuke; Gak, Igor A; Weisswange, Ina; Mansfeld, Jörg; Buchholz, Frank; Hyman, Anthony A; Mann, Matthias.

Cell ; 163(3): 712-23, 2015 Oct 22.

Artigo em Inglês | MEDLINE | ID: mdl-26496610

10.

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.

Patel, Avinash; Lee, Hyun O; Jawerth, Louise; Maharana, Shovamayee; Jahnel, Marcus; Hein, Marco Y; Stoynov, Stoyno; Mahamid, Julia; Saha, Shambaditya; Franzmann, Titus M; Pozniakovski, Andrej; Poser, Ina; Maghelli, Nicola; Royer, Loic A; Weigert, Martin; Myers, Eugene W; Grill, Stephan; Drechsel, David; Hyman, Anthony A; Alberti, Simon.

Cell ; 162(5): 1066-77, 2015 Aug 27.

Artigo em Inglês | MEDLINE | ID: mdl-26317470

11.

SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA.

Maharana, Shovamayee; Kretschmer, Stefanie; Hunger, Susan; Yan, Xiao; Kuster, David; Traikov, Sofia; Zillinger, Thomas; Gentzel, Marc; Elangovan, Shobha; Dasgupta, Padmanava; Chappidi, Nagaraja; Lucas, Nadja; Maser, Katharina Isabell; Maatz, Henrike; Rapp, Alexander; Marchand, Virginie; Chang, Young-Tae; Motorin, Yuri; Hubner, Norbert; Hartmann, Gunther; Hyman, Anthony A; Alberti, Simon; Lee-Kirsch, Min Ae.

Mol Cell ; 82(19): 3712-3728.e10, 2022 10 06.

Artigo em Inglês | MEDLINE | ID: mdl-36150385

12.

Biomolecular condensates: organizers of cellular biochemistry.

Banani, Salman F; Lee, Hyun O; Hyman, Anthony A; Rosen, Michael K.

Nat Rev Mol Cell Biol ; 18(5): 285-298, 2017 05.

Artigo em Inglês | MEDLINE | ID: mdl-28225081

13.

A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility.

Bassik, Michael C; Kampmann, Martin; Lebbink, Robert Jan; Wang, Shuyi; Hein, Marco Y; Poser, Ina; Weibezahn, Jimena; Horlbeck, Max A; Chen, Siyuan; Mann, Matthias; Hyman, Anthony A; Leproust, Emily M; McManus, Michael T; Weissman, Jonathan S.

Cell ; 152(4): 909-22, 2013 Feb 14.

Artigo em Inglês | MEDLINE | ID: mdl-23394947

14.

Liquid-liquid phase separation in biology.

Hyman, Anthony A; Weber, Christoph A; Jülicher, Frank.

Annu Rev Cell Dev Biol ; 30: 39-58, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-25288112

15.

Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions.

Frost, Adam; Elgort, Marc G; Brandman, Onn; Ives, Clinton; Collins, Sean R; Miller-Vedam, Lakshmi; Weibezahn, Jimena; Hein, Marco Y; Poser, Ina; Mann, Matthias; Hyman, Anthony A; Weissman, Jonathan S.

Cell ; 149(6): 1339-52, 2012 Jun 08.

Artigo em Inglês | MEDLINE | ID: mdl-22682253

16.

A genome-scale resource for in vivo tag-based protein function exploration in C. elegans.

Sarov, Mihail; Murray, John I; Schanze, Kristin; Pozniakovski, Andrei; Niu, Wei; Angermann, Karolin; Hasse, Susanne; Rupprecht, Michaela; Vinis, Elisabeth; Tinney, Matthew; Preston, Elicia; Zinke, Andrea; Enst, Susanne; Teichgraber, Tina; Janette, Judith; Reis, Kadri; Janosch, Stephan; Schloissnig, Siegfried; Ejsmont, Radoslaw K; Slightam, Cindie; Xu, Xiao; Kim, Stuart K; Reinke, Valerie; Stewart, A Francis; Snyder, Michael; Waterston, Robert H; Hyman, Anthony A.

Cell ; 150(4): 855-66, 2012 Aug 17.

Artigo em Inglês | MEDLINE | ID: mdl-22901814

17.

Local and dynamic regulation of neuronal glycolysis in vivo.

Wolfe, Aaron D; Koberstein, John N; Smith, Chadwick B; Stewart, Melissa L; Gonzalez, Ian J; Hammarlund, Marc; Hyman, Anthony A; Stork, Philip J S; Goodman, Richard H; Colón-Ramos, Daniel A.

Proc Natl Acad Sci U S A ; 121(3): e2314699121, 2024 Jan 16.

Artigo em Inglês | MEDLINE | ID: mdl-38198527

18.

CD-CODE: crowdsourcing condensate database and encyclopedia.

Rostam, Nadia; Ghosh, Soumyadeep; Chow, Chi Fung Willis; Hadarovich, Anna; Landerer, Cedric; Ghosh, Rajat; Moon, HongKee; Hersemann, Lena; Mitrea, Diana M; Klein, Isaac A; Hyman, Anthony A; Toth-Petroczy, Agnes.

Nat Methods ; 20(5): 673-676, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-37024650

19.

Samurai sword sets spindle size.

Reber, Simone; Hyman, Anthony A.

Cell ; 147(6): 1224-5, 2011 Dec 09.

Artigo em Inglês | MEDLINE | ID: mdl-22153069

20.

A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue.

Green, Rebecca A; Kao, Huey-Ling; Audhya, Anjon; Arur, Swathi; Mayers, Jonathan R; Fridolfsson, Heidi N; Schulman, Monty; Schloissnig, Siegfried; Niessen, Sherry; Laband, Kimberley; Wang, Shaohe; Starr, Daniel A; Hyman, Anthony A; Schedl, Tim; Desai, Arshad; Piano, Fabio; Gunsalus, Kristin C; Oegema, Karen.

Cell ; 145(3): 470-82, 2011 Apr 29.

Artigo em Inglês | MEDLINE | ID: mdl-21529718

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