Detalhe da pesquisa
1.
Detailed mechanistic analysis of gevokizumab, an allosteric anti-IL-1ß antibody with differential receptor-modulating properties.
J Pharmacol Exp Ther
; 348(1): 202-15, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24194526
2.
Kinetic approach to pathway attenuation using XOMA 052, a regulatory therapeutic antibody that modulates interleukin-1beta activity.
J Biol Chem
; 285(27): 20607-14, 2010 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20410301
3.
Distinguishing features of a novel humanized anti-EGFR monoclonal antibody based on cetuximab with superior antitumor efficacy.
Expert Opin Biol Ther
; 21(11): 1491-1507, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34632911
4.
Structural basis of HLX10 PD-1 receptor recognition, a promising anti-PD-1 antibody clinical candidate for cancer immunotherapy.
PLoS One
; 16(12): e0257972, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34972111
5.
Characterization of murine CEACAM1 in vivo reveals low expression on CD8+ T cells and no tumor growth modulating activity by anti-CEACAM1 mAb CC1.
Oncotarget
; 9(77): 34459-34470, 2018 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30349641
6.
Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies.
Mol Biol Cell
; 13(2): 723-37, 2002 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-11854425
7.
Application of an In Vivo Hepatic Triacylglycerol Production Method in the Setting of a High-Fat Diet in Mice.
Nutrients
; 9(1)2016 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28036028
8.
Selective allosteric antibodies to the insulin receptor for the treatment of hyperglycemic and hypoglycemic disorders.
J Diabetes Sci Technol
; 8(4): 865-73, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24876415
9.
Inhibition of insulin receptor function by a human, allosteric monoclonal antibody: a potential new approach for the treatment of hyperinsulinemic hypoglycemia.
MAbs
; 6(1): 262-72, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24423625
10.
Enhancement of antibody fragment secretion into the Escherichia coli periplasm by co-expression with the peptidyl prolyl isomerase, FkpA, in the cytoplasm.
J Immunol Methods
; 394(1-2): 10-21, 2013 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23624043
11.
Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice.
Atherosclerosis
; 216(2): 313-20, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21411094
12.
XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1ß-mediated diseases.
MAbs
; 3(1): 49-60, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21048425
13.
Homo- and hetero-oligomerization of beta-arrestins in living cells.
J Biol Chem
; 280(48): 40210-5, 2005 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-16199535
14.
Constitutive agonist-independent CCR5 oligomerization and antibody-mediated clustering occurring at physiological levels of receptors.
J Biol Chem
; 277(38): 34666-73, 2002 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-12089144