Pesquisa | BVS Violência e Saúde

1.

Precise therapeutic gene correction by a simple nuclease-induced double-stranded break.

Iyer, Sukanya; Suresh, Sneha; Guo, Dongsheng; Daman, Katelyn; Chen, Jennifer C J; Liu, Pengpeng; Zieger, Marina; Luk, Kevin; Roscoe, Benjamin P; Mueller, Christian; King, Oliver D; Emerson, Charles P; Wolfe, Scot A.

Nature ; 568(7753): 561-565, 2019 04.

Artigo em Inglês | MEDLINE | ID: mdl-30944467

2.

Functional restoration of mouse Nf1 nonsense alleles in differentiated cultured neurons.

Wu, Chan; Iyer, Sukanya; Wolfe, Scot A; Jacobson, Allan.

J Hum Genet ; 67(11): 661-668, 2022 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-35945271

3.

Absolute quantitative measurement of transcriptional kinetic parameters in vivo.

Iyer, Sukanya; Park, Bo Ryoung; Kim, Minsu.

Nucleic Acids Res ; 44(18): e142, 2016 Oct 14.

Artigo em Inglês | MEDLINE | ID: mdl-27378780

4.

Expression optimization and synthetic gene networks in cell-free systems.

Karig, David K; Iyer, Sukanya; Simpson, Michael L; Doktycz, Mitchel J.

Nucleic Acids Res ; 40(8): 3763-74, 2012 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-22180537

5.

Optimization of Nuclear Localization Signal Composition Improves CRISPR-Cas12a Editing Rates in Human Primary Cells.

Luk, Kevin; Liu, Pengpeng; Zeng, Jing; Wang, Yetao; Maitland, Stacy A; Idrizi, Feston; Ponnienselvan, Karthikeyan; Iyer, Sukanya; Zhu, Lihua Julie; Luban, Jeremy; Bauer, Daniel E; Wolfe, Scot A.

GEN Biotechnol ; 1(3): 271-284, 2022 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-38405215

6.

Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors.

Iyer, Sukanya; Mir, Aamir; Vega-Badillo, Joel; Roscoe, Benjamin P; Ibraheim, Raed; Zhu, Lihua Julie; Lee, Jooyoung; Liu, Pengpeng; Luk, Kevin; Mintzer, Esther; Guo, Dongsheng; Soares de Brito, Josias; Emerson, Charles P; Zamore, Phillip D; Sontheimer, Erik J; Wolfe, Scot A.

CRISPR J ; 5(5): 685-701, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-36070530

7.

Novel MRI deformation-heterogeneity radiomic features are associated with molecular subgroups and overall survival in pediatric medulloblastoma: Preliminary findings from a multi-institutional study.

Iyer, Sukanya; Ismail, Marwa; Tamrazi, Benita; Salloum, Ralph; de Blank, Peter; Margol, Ashley; Correa, Ramon; Chen, Jonathan; Bera, Kaustav; Statsevych, Volodymyr; Ho, Mai-Lan; Vaidya, Pranjal; Verma, Ruchika; Hawes, Debra; Judkins, Alexander; Fu, Pingfu; Madabhushi, Anant; Tiwari, Pallavi.

Front Oncol ; 12: 915143, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-36620600

8.

A Protease-Activated Fluorescent Probe Allows Rapid Visualization of Keratinocyte Carcinoma during Excision.

Walker, Ethan; Liu, Yiqiao; Kim, InYoung; Biro, Mark; Iyer, Sukanya Raj; Ezaldein, Harib; Scott, Jeffrey; Merati, Miesha; Mistur, Rachel; Zhou, Bo; Straight, Brian; Yim, Joshua J; Bogyo, Matthew; Mann, Margaret; Wilson, David L; Basilion, James P; Popkin, Daniel L.

Cancer Res ; 80(10): 2045-2055, 2020 05 15.

Artigo em Inglês | MEDLINE | ID: mdl-32132111

9.

Molecular imaging and validation of margins in surgically excised nonmelanoma skin cancer specimens.

Liu, Yiqiao; Walker, Ethan; Iyer, Sukanya Raj; Biro, Mark; Kim, InYoung; Zhou, Bo; Straight, Brian; Bogyo, Matthew; Basilion, James P; Popkin, Daniel L; Wilson, David L.

J Med Imaging (Bellingham) ; 6(1): 016001, 2019 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-30915384

10.

Distinct mechanisms coordinate transcription and translation under carbon and nitrogen starvation in Escherichia coli.

Iyer, Sukanya; Le, Dai; Park, Bo Ryoung; Kim, Minsu.

Nat Microbiol ; 3(6): 741-748, 2018 06.

Artigo em Inglês | MEDLINE | ID: mdl-29760462

11.

Thrombin-mediated transcriptional regulation using DNA aptamers in DNA-based cell-free protein synthesis.

Iyer, Sukanya; Doktycz, Mitchel J.

ACS Synth Biol ; 3(6): 340-6, 2014 Jun 20.

Artigo em Inglês | MEDLINE | ID: mdl-24059754

12.

Multi-input regulation and logic with T7 promoters in cells and cell-free systems.

Iyer, Sukanya; Karig, David K; Norred, S Elizabeth; Simpson, Michael L; Doktycz, Mitchel J.

PLoS One ; 8(10): e78442, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-24194933

13.

Surface charge- and space-dependent transport of proteins in crowded environments of nanotailored posts.

Choi, Chang Kyoung; Fowlkes, Jason D; Retterer, Scott T; Siuti, Piro; Iyer, Sukanya; Doktycz, Mitchel J.

ACS Nano ; 4(6): 3345-55, 2010 Jun 22.

Artigo em Inglês | MEDLINE | ID: mdl-20515056

14.

Multilayered nanoparticles for siRNA delivery.

Iyer, Sukanya; Doktycz, Mitchel J.

Nanomedicine (Lond) ; 7(11): 1653-4, 2012 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-23346569

15.

Rationally designed vaccines.

Iyer, Sukanya; Doktycz, Mitchel J.

Nanomedicine (Lond) ; 7(11): 1654, 2012 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-23346570

16.

Nanozymes for antiviral therapy.

Iyer, Sukanya; Doktycz, Mitchel J.

Nanomedicine (Lond) ; 7(11): 1654-5, 2012 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-23346571

17.

Shear-activated nanotherapeutics.

Iyer, Sukanya; Doktycz, Mitchel J.

Nanomedicine (Lond) ; 7(11): 1653, 2012 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-23210713

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Precise therapeutic gene correction by a simple nuclease-induced double-stranded break.

Functional restoration of mouse Nf1 nonsense alleles in differentiated cultured neurons.

Absolute quantitative measurement of transcriptional kinetic parameters in vivo.

Expression optimization and synthetic gene networks in cell-free systems.

Optimization of Nuclear Localization Signal Composition Improves CRISPR-Cas12a Editing Rates in Human Primary Cells.

Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors.

Novel MRI deformation-heterogeneity radiomic features are associated with molecular subgroups and overall survival in pediatric medulloblastoma: Preliminary findings from a multi-institutional study.

A Protease-Activated Fluorescent Probe Allows Rapid Visualization of Keratinocyte Carcinoma during Excision.

Molecular imaging and validation of margins in surgically excised nonmelanoma skin cancer specimens.

Distinct mechanisms coordinate transcription and translation under carbon and nitrogen starvation in Escherichia coli.

Thrombin-mediated transcriptional regulation using DNA aptamers in DNA-based cell-free protein synthesis.

Multi-input regulation and logic with T7 promoters in cells and cell-free systems.

Surface charge- and space-dependent transport of proteins in crowded environments of nanotailored posts.

Multilayered nanoparticles for siRNA delivery.

Rationally designed vaccines.

Nanozymes for antiviral therapy.

Shear-activated nanotherapeutics.