Detalhe da pesquisa
1.
Utility of in vivo metabolomics to support read-across for UVCB substances under REACH.
Arch Toxicol
; 98(3): 755-768, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38265474
2.
Demonstrating the reliability of in vivo metabolomics based chemical grouping: towards best practice.
Arch Toxicol
; 98(4): 1111-1123, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38368582
3.
Embedding routine health care data in clinical trials: with great power comes great responsibility.
Neth Heart J
; 32(3): 106-115, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38224411
4.
Influence of pregnancy and non-fasting conditions on the plasma metabolome in a rat prenatal toxicity study.
Arch Toxicol
; 95(9): 2941-2959, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34327559
5.
Setting the stage for next-generation risk assessment with non-animal approaches: the EU-ToxRisk project experience.
Arch Toxicol
; 94(10): 3581-3592, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32886186
6.
Analysis of metabolome changes in the bile acid pool in feces and plasma of antibiotic-treated rats.
Toxicol Appl Pharmacol
; 363: 79-87, 2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30502395
7.
Metabolomics as read-across tool: An example with 3-aminopropanol and 2-aminoethanol.
Regul Toxicol Pharmacol
; 108: 104442, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31421187
8.
Microbiome-related metabolite changes in gut tissue, cecum content and feces of rats treated with antibiotics.
Toxicol Appl Pharmacol
; 355: 198-210, 2018 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30008377
9.
Gut microbiome-related metabolic changes in plasma of antibiotic-treated rats.
Arch Toxicol
; 91(10): 3439-3454, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28337503
10.
Metabolomics as read-across tool: A case study with phenoxy herbicides.
Regul Toxicol Pharmacol
; 81: 288-304, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27637788
11.
Metabolomics: a tool for early detection of toxicological effects and an opportunity for biology based grouping of chemicals-from QSAR to QBAR.
Mutat Res
; 746(2): 144-50, 2012 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22305969
12.
Succinate dehydrogenase inhibitors: in silico flux analysis and in vivo metabolomics investigations show no severe metabolic consequences for rats and humans.
Food Chem Toxicol
; 150: 112085, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33636213
13.
In vitro mammalian metabolism of the mitosis inhibitor zoxamide and the relationship to its in vitro toxicity.
Xenobiotica
; 40(1): 72-82, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20001673
14.
Pyrazolopyrimidinediones are selective agents for Helicobacter pylori that suppress growth through inhibition of glutamate racemase (MurI).
Antimicrob Agents Chemother
; 53(8): 3331-6, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19433553
15.
Added value of plasma metabolomics to describe maternal effects in rat maternal and prenatal toxicity studies.
Toxicol Lett
; 301: 42-52, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30414988
16.
A variable degree of intrauterine and postnatal growth retardation in a family with a missense mutation in the insulin-like growth factor I receptor.
J Clin Endocrinol Metab
; 91(8): 3062-70, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16757531
17.
Metabolite profiles of rats in repeated dose toxicological studies after oral and inhalative exposure.
Toxicol Lett
; 255: 11-23, 2016 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27153797
18.
Delipidation of the phosphatidylcholine exchange protein from beef liver by detergents.
Biochim Biophys Acta
; 398(3): 401-14, 1975 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-809056
19.
Action of phospholipases on the phosphatidylcholine exchange protein from beef liver.
Biochim Biophys Acta
; 398(3): 415-23, 1975 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-1174523
20.
Effects of total-body irradiation on growth, thyroid and pituitary gland in rhesus monkeys.
Radiother Oncol
; 51(2): 187-92, 1999 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-10435812