Pesquisa | BVS Violência e Saúde

1.

Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency.

Oda, Hirotsugu; Manthiram, Kalpana; Chavan, Pallavi Pimpale; Rieser, Eva; Veli, Önay; Kaya, Öykü; Rauch, Charles; Nakabo, Shuichiro; Kuehn, Hye Sun; Swart, Mariël; Wang, Yanli; Çelik, Nisa Ilgim; Molitor, Anne; Ziaee, Vahid; Movahedi, Nasim; Shahrooei, Mohammad; Parvaneh, Nima; Alipour-Olyei, Nasrin; Carapito, Raphael; Xu, Qin; Preite, Silvia; Beck, David B; Chae, Jae Jin; Nehrebecky, Michele; Ombrello, Amanda K; Hoffmann, Patrycja; Romeo, Tina; Deuitch, Natalie T; Matthíasardóttir, Brynja; Mullikin, James; Komarow, Hirsh; Stoddard, Jennifer; Niemela, Julie; Dobbs, Kerry; Sweeney, Colin L; Anderton, Holly; Lawlor, Kate E; Yoshitomi, Hiroyuki; Yang, Dan; Boehm, Manfred; Davis, Jeremy; Mudd, Pamela; Randazzo, Davide; Tsai, Wanxia Li; Gadina, Massimo; Kaplan, Mariana J; Toguchida, Junya; Mayer, Christian T; Rosenzweig, Sergio D; Notarangelo, Luigi D.

Nat Immunol ; 25(5): 764-777, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38609546

2.

Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells.

Kolev, Martin; West, Erin E; Kunz, Natalia; Chauss, Daniel; Moseman, E Ashley; Rahman, Jubayer; Freiwald, Tilo; Balmer, Maria L; Lötscher, Jonas; Dimeloe, Sarah; Rosser, Elizabeth C; Wedderburn, Lucy R; Mayer-Barber, Katrin D; Bohrer, Andrea; Lavender, Paul; Cope, Andrew; Wang, Luopin; Kaplan, Mariana J; Moutsopoulos, Niki M; McGavern, Dorian; Holland, Steven M; Hess, Christoph; Kazemian, Majid; Afzali, Behdad; Kemper, Claudia.

Immunity ; 52(3): 513-527.e8, 2020 03 17.

Artigo em Inglês | MEDLINE | ID: mdl-32187519

3.

Mitochondrial dysfunction in the erythroid compartment.

Kaplan, Mariana J.

Nat Immunol ; 22(11): 1354-1355, 2021 11.

Artigo em Inglês | MEDLINE | ID: mdl-34671144

4.

NETched in Stone.

O'Neil, Liam J; Kaplan, Mariana J.

Immunity ; 51(3): 413-414, 2019 09 17.

Artigo em Inglês | MEDLINE | ID: mdl-31533050

5.

Of larks and owls.

Kaplan, Mariana J.

Nat Immunol ; 21(2): 104-105, 2020 02.

Artigo em Inglês | MEDLINE | ID: mdl-31932811

6.

Low-density granulocytes in systemic autoimmunity and autoinflammation.

Carmona-Rivera, Carmelo; Kaplan, Mariana J.

Immunol Rev ; 314(1): 313-325, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36305174

7.

Metabolic alterations of the immune system in the pathogenesis of autoimmune diseases.

Blanco, Luz P; Kaplan, Mariana J.

PLoS Biol ; 21(4): e3002084, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-37098006

8.

Inhibition of JAK-STAT pathway corrects salivary gland inflammation and interferon driven immune activation in Sjögren's disease.

Gupta, Sarthak; Yamada, Eiko; Nakamura, Hiroyuki; Perez, Paola; Pranzatelli, Thomas Jf; Dominick, Kalie; Jang, Shyh-Ing; Abed, Mehdi; Martin, Daniel; Burbelo, Peter; Zheng, ChangYu; French, Ben; Alevizos, Ilias; Khavandgar, Zohreh; Beach, Margaret; Pelayo, Eileen; Walitt, Brian; Hasni, Sarfaraz; Kaplan, Mariana J; Tandon, Mayank; Magone, Maria Teresa; Kleiner, David E; Chiorini, John A; Baer, Alan; Warner, Blake M.

Ann Rheum Dis ; 2024 Mar 25.

Artigo em Inglês | MEDLINE | ID: mdl-38527764

9.

FOXM1 network in association with TREM1 suppression regulates NET formation in diabetic foot ulcers.

Sawaya, Andrew P; Stone, Rivka C; Mehdizadeh, Spencer; Pastar, Irena; Worrell, Stephen; Balukoff, Nathan C; Kaplan, Mariana J; Tomic-Canic, Marjana; Morasso, Maria I.

EMBO Rep ; 23(8): e54558, 2022 08 03.

Artigo em Inglês | MEDLINE | ID: mdl-35856334

10.

Single-Cell Analysis Reveals the Range of Transcriptional States of Circulating Human Neutrophils.

Wigerblad, Gustaf; Cao, Qilin; Brooks, Stephen; Naz, Faiza; Gadkari, Manasi; Jiang, Kan; Gupta, Sarthak; O'Neil, Liam; Dell'Orso, Stefania; Kaplan, Mariana J; Franco, Luis M.

J Immunol ; 209(4): 772-782, 2022 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-35858733

11.

Neutrophils in Inflammatory Bone Diseases.

Carmona-Rivera, Carmelo; Kaplan, Mariana J; O'Neil, Liam J.

Curr Osteoporos Rep ; 22(2): 280-289, 2024 04.

Artigo em Inglês | MEDLINE | ID: mdl-38418800

12.

Transmission disequilibrium analysis of whole genome data in childhood-onset systemic lupus erythematosus.

Vazzana, Kathleen M; Musolf, Anthony M; Bailey-Wilson, Joan E; Hiraki, Linda T; Silverman, Earl D; Scott, Christiaan; Dalgard, Clifton L; Hasni, Sarfaraz; Deng, Zuoming; Kaplan, Mariana J; Lewandowski, Laura B.

Genes Immun ; 24(4): 200-206, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37488248

13.

Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease.

Beck, David B; Ferrada, Marcela A; Sikora, Keith A; Ombrello, Amanda K; Collins, Jason C; Pei, Wuhong; Balanda, Nicholas; Ross, Daron L; Ospina Cardona, Daniela; Wu, Zhijie; Patel, Bhavisha; Manthiram, Kalpana; Groarke, Emma M; Gutierrez-Rodrigues, Fernanda; Hoffmann, Patrycja; Rosenzweig, Sofia; Nakabo, Shuichiro; Dillon, Laura W; Hourigan, Christopher S; Tsai, Wanxia L; Gupta, Sarthak; Carmona-Rivera, Carmelo; Asmar, Anthony J; Xu, Lisha; Oda, Hirotsugu; Goodspeed, Wendy; Barron, Karyl S; Nehrebecky, Michele; Jones, Anne; Laird, Ryan S; Deuitch, Natalie; Rowczenio, Dorota; Rominger, Emily; Wells, Kristina V; Lee, Chyi-Chia R; Wang, Weixin; Trick, Megan; Mullikin, James; Wigerblad, Gustaf; Brooks, Stephen; Dell'Orso, Stefania; Deng, Zuoming; Chae, Jae J; Dulau-Florea, Alina; Malicdan, May C V; Novacic, Danica; Colbert, Robert A; Kaplan, Mariana J; Gadina, Massimo; Savic, Sinisa.

N Engl J Med ; 383(27): 2628-2638, 2020 12 31.

Artigo em Inglês | MEDLINE | ID: mdl-33108101

14.

Neutrophil extracellular trap-associated carbamylation and histones trigger osteoclast formation in rheumatoid arthritis.

O'Neil, Liam J; Oliveira, Christopher B; Wang, Xinghao; Navarrete, Mario; Barrera-Vargas, Ana; Merayo-Chalico, Javier; Aljahdali, Rwan; Aguirre-Aguilar, Eduardo; Carlucci, Philip; Kaplan, Mariana J; Carmona-Rivera, Carmelo.

Ann Rheum Dis ; 82(5): 630-638, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-36737106

15.

Coexisting autoantibodies against transcription factor Sp4 are associated with decreased cancer risk in patients with dermatomyositis with anti-TIF1Î³ autoantibodies.

Hosono, Yuji; Sie, Brandon; Pinal-Fernandez, Iago; Pak, Katherine; Mecoli, Christopher A; Casal-Dominguez, Maria; Warner, Blake M; Kaplan, Mariana J; Albayda, Jemima; Danoff, Sonye; Lloyd, Thomas E; Paik, Julie J; Tiniakou, Eleni; Aggarwal, Rohit; Oddis, Chester V; Moghadam-Kia, Siamak; Carmona-Rivera, Carmelo; Milisenda, Jose César; Grau-Junyent, Josep Maria; Selva-O'Callaghan, Albert; Christopher-Stine, Lisa; Larman, H Benjamin; Mammen, Andrew Lee.

Ann Rheum Dis ; 82(2): 246-252, 2023 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-36008132

16.

HAL-X: Scalable hierarchical clustering for rapid and tunable single-cell analysis.

Anibal, James; Day, Alexandre G; Bahadiroglu, Erol; O'Neil, Liam; Phan, Long; Peltekian, Alec; Erez, Amir; Kaplan, Mariana; Altan-Bonnet, Grégoire; Mehta, Pankaj.

PLoS Comput Biol ; 18(10): e1010349, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-36191000

17.

Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus.

Goel, Rishi R; Wang, Xinghao; O'Neil, Liam J; Nakabo, Shuichiro; Hasneen, Kowser; Gupta, Sarthak; Wigerblad, Gustaf; Blanco, Luz P; Kopp, Jeffrey B; Morasso, Maria I; Kotenko, Sergei V; Yu, Zu-Xi; Carmona-Rivera, Carmelo; Kaplan, Mariana J.

Proc Natl Acad Sci U S A ; 117(10): 5409-5419, 2020 03 10.

Artigo em Inglês | MEDLINE | ID: mdl-32094169

18.

Immunity to commensal skin fungi promotes psoriasiform skin inflammation.

Hurabielle, Charlotte; Link, Verena M; Bouladoux, Nicolas; Han, Seong-Ji; Merrill, Eric Dean; Lightfoot, Yaima L; Seto, Nickie; Bleck, Christopher K E; Smelkinson, Margery; Harrison, Oliver J; Linehan, Jonathan L; Tamoutounour, Samira; Lionakis, Michail S; Kaplan, Mariana J; Nakajima, Saeko; Belkaid, Yasmine.

Proc Natl Acad Sci U S A ; 117(28): 16465-16474, 2020 07 14.

Artigo em Inglês | MEDLINE | ID: mdl-32601220

19.

Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis.

Jing, Chenzhi; Castro-Dopico, Tomas; Richoz, Nathan; Tuong, Zewen K; Ferdinand, John R; Lok, Laurence S C; Loudon, Kevin W; Banham, Gemma D; Mathews, Rebeccah J; Cader, Zaeem; Fitzpatrick, Susan; Bashant, Kathleen R; Kaplan, Mariana J; Kaser, Arthur; Johnson, Randall S; Murphy, Michael P; Siegel, Richard M; Clatworthy, Menna R.

Proc Natl Acad Sci U S A ; 117(26): 15160-15171, 2020 06 30.

Artigo em Inglês | MEDLINE | ID: mdl-32541026

20.

Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism.

Gupta, Sarthak; Nakabo, Shuichiro; Blanco, Luz P; O'Neil, Liam J; Wigerblad, Gustaf; Goel, Rishi R; Mistry, Pragnesh; Jiang, Kan; Carmona-Rivera, Carmelo; Chan, Diana W; Wang, Xinghao; Pedersen, Hege L; Gadkari, Manasi; Howe, Katherine N; Naz, Faiza; Dell'Orso, Stefania; Hasni, Sarfaraz A; Dempsey, Caeden; Buscetta, Ashley; Frischmeyer-Guerrerio, Pamela A; Kruszka, Paul; Muenke, Maximilian; Franco, Luis M; Sun, Hong-Wei; Kaplan, Mariana J.

Proc Natl Acad Sci U S A ; 117(28): 16481-16491, 2020 07 14.

Artigo em Inglês | MEDLINE | ID: mdl-32601182

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