Pesquisa | BVS Violência e Saúde

1.

Regional Histopathology and Prostate MRI Positivity: A Secondary Analysis of the PROMIS Trial.

Stavrinides, Vasilis; Norris, Joseph M; Karapanagiotis, Solon; Giganti, Francesco; Grey, Alistair; Trahearn, Nick; Freeman, Alex; Haider, Aiman; Carmona Echeverría, Lina María; Bott, Simon R J; Brown, Louise C; Burns-Cox, Nicholas; Dudderidge, Timothy J; El-Shater Bosaily, Ahmed; Ghei, Maneesh; Henderson, Alastair; Hindley, Richard G; Kaplan, Richard S; Oldroyd, Robert; Parker, Chris; Persad, Raj; Rosario, Derek J; Shergill, Iqbal S; Winkler, Mathias; Kirkham, Alex; Punwani, Shonit; Whitaker, Hayley C; Ahmed, Hashim U; Emberton, Mark.

Radiology ; 307(1): e220762, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-36511804

2.

High EMSY expression defines a BRCA-like subgroup of high-grade serous ovarian carcinoma with prolonged survival and hypersensitivity to platinum.

Hollis, Robert L; Churchman, Michael; Michie, Caroline O; Rye, Tzyvia; Knight, Laura; McCavigan, Andrena; Perren, Timothy; Williams, Alistair R W; McCluggage, W Glenn; Kaplan, Richard S; Jayson, Gordon C; Oza, Amit; Harkin, D Paul; Herrington, C Simon; Kennedy, Richard; Gourley, Charlie.

Cancer ; 125(16): 2772-2781, 2019 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-31154673

3.

Exploratory outcome analyses according to stage and/or residual disease in the ICON7 trial of carboplatin and paclitaxel with or without bevacizumab for newly diagnosed ovarian cancer.

González Martín, Antonio; Oza, Amit M; Embleton, Andrew C; Pfisterer, Jacobus; Ledermann, Jonathan A; Pujade-Lauraine, Eric; Kristensen, Gunnar; Bertrand, Monique A; Beale, Philip; Cervantes, Andrés; Kent, Emma; Kaplan, Richard S; Parmar, Mahesh K B; Scotto, Nana; Perren, Timothy J.

Gynecol Oncol ; 152(1): 53-60, 2019 01.

Artigo em Inglês | MEDLINE | ID: mdl-30449719

4.

Comprehensive pharmacogenetic profiling of the epidermal growth factor receptor pathway for biomarkers of response to, and toxicity from, cetuximab.

Madi, Ayman; Fisher, David; Maughan, Timothy S; Colley, James P; Meade, Angela M; Tejpar, Sabine; Van den Bosch, Ben; Maynard, Julie; Humphreys, Vikki; Wasan, Harpreet; Adams, Richard A; Idziaszczyk, Shelley; Harris, Rebecca; Kaplan, Richard S; Cheadle, Jeremy P.

J Med Genet ; 54(8): 567-571, 2017 08.

Artigo em Inglês | MEDLINE | ID: mdl-28283541

5.

Quality of life with cediranib in relapsed ovarian cancer: The ICON6 phase 3 randomized clinical trial.

Stark, Dan P; Cook, Adrian; Brown, Julia M; Brundage, Michael D; Embleton, Andrew C; Kaplan, Richard S; Raja, Fharat A; Swart, Ann Marie W; Velikova, Galina; Qian, Wendi; Ledermann, Jonathan A.

Cancer ; 123(14): 2752-2761, 2017 Jul 15.

Artigo em Inglês | MEDLINE | ID: mdl-28339098

6.

Cediranib in patients with relapsed platinum-sensitive ovarian cancer (ICON6): a randomised, double-blind, placebo-controlled phase 3 trial.

Ledermann, Jonathan A; Embleton, Andrew C; Raja, Fharat; Perren, Timothy J; Jayson, Gordon C; Rustin, Gordon J S; Kaye, Stan B; Hirte, Hal; Eisenhauer, Elizabeth; Vaughan, Michelle; Friedlander, Michael; González-Martín, Antonio; Stark, Daniel; Clark, Elizabeth; Farrelly, Laura; Swart, Ann Marie; Cook, Adrian; Kaplan, Richard S; Parmar, Mahesh K B.

Lancet ; 387(10023): 1066-1074, 2016 Mar 12.

Artigo em Inglês | MEDLINE | ID: mdl-27025186

7.

Imaging Modality and Frequency in Surveillance of Stage I Seminoma Testicular Cancer: Results From a Randomized, Phase III, Noninferiority Trial (TRISST).

Joffe, Johnathan K; Cafferty, Fay H; Murphy, Laura; Rustin, Gordon J S; Sohaib, Syed A; Gabe, Rhian; Stenning, Sally P; James, Elizabeth; Noor, Dipa; Wade, Simona; Schiavone, Francesca; Swift, Sarah; Dunwoodie, Elaine; Hall, Marcia; Sharma, Anand; Braybrooke, Jeremy; Shamash, Jonathan; Logue, John; Taylor, Henry H; Hennig, Ivo; White, Jeff; Rudman, Sarah; Worlding, Jane; Bloomfield, David; Faust, Guy; Glen, Hilary; Jones, Rachel; Seckl, Michael; MacDonald, Graham; Sreenivasan, Thiagarajan; Kumar, Satish; Protheroe, Andrew; Venkitaraman, Ramachandran; Mazhar, Danish; Coyle, Victoria; Highley, Martin; Geldart, Tom; Laing, Robert; Kaplan, Richard S; Huddart, Robert A.

J Clin Oncol ; 40(22): 2468-2478, 2022 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-35298280

8.

False Positive Multiparametric Magnetic Resonance Imaging Phenotypes in the Biopsy-naïve Prostate: Are They Distinct from Significant Cancer-associated Lesions? Lessons from PROMIS.

Stavrinides, Vasilis; Syer, Tom; Hu, Yipeng; Giganti, Francesco; Freeman, Alex; Karapanagiotis, Solon; Bott, Simon R J; Brown, Louise C; Burns-Cox, Nicholas; Dudderidge, Timothy J; Bosaily, Ahmed El-Shater; Frangou, Elena; Ghei, Maneesh; Henderson, Alastair; Hindley, Richard G; Kaplan, Richard S; Oldroyd, Robert; Parker, Chris; Persad, Raj; Rosario, Derek J; Shergill, Iqbal S; Echeverria, Lina M Carmona; Norris, Joseph M; Winkler, Mathias; Barratt, Dean; Kirkham, Alex; Punwani, Shonit; Whitaker, Hayley C; Ahmed, Hashim U; Emberton, Mark.

Eur Urol ; 79(1): 20-29, 2021 01.

Artigo em Inglês | MEDLINE | ID: mdl-33051065

9.

In-depth Clinical and Biological Exploration of DNA Damage Immune Response as a Biomarker for Oxaliplatin Use in Colorectal Cancer.

Malla, Sudhir B; Fisher, David J; Domingo, Enric; Blake, Andrew; Hassanieh, Sylvana; Redmond, Keara L; Richman, Susan D; Youdell, Michael; Walker, Steven M; Logan, Gemma E; Chatzipli, Aikaterina; Amirkhah, Raheleh; Humphries, Matthew P; Craig, Stephanie G; McDermott, Ultan; Seymour, Matthew T; Morton, Dion G; Quirke, Philip; West, Nicholas P; Salto-Tellez, Manuel; Kennedy, Richard D; Johnston, Patrick G; Tomlinson, Ian; Koelzer, Viktor H; Campo, Letitia; Kaplan, Richard S; Longley, Daniel B; Lawler, Mark; Maughan, Timothy S; Brown, Louise C; Dunne, Philip D.

Clin Cancer Res ; 27(1): 288-300, 2021 01 01.

Artigo em Inglês | MEDLINE | ID: mdl-33028592

10.

What Type of Prostate Cancer Is Systematically Overlooked by Multiparametric Magnetic Resonance Imaging? An Analysis from the PROMIS Cohort.

Norris, Joseph M; Carmona Echeverria, Lina M; Bott, Simon R J; Brown, Louise C; Burns-Cox, Nick; Dudderidge, Tim; El-Shater Bosaily, Ahmed; Frangou, Eleni; Freeman, Alex; Ghei, Maneesh; Henderson, Alastair; Hindley, Richard G; Kaplan, Richard S; Kirkham, Alex; Oldroyd, Robert; Parker, Chris; Persad, Raj; Punwani, Shonit; Rosario, Derek J; Shergill, Iqbal S; Stavrinides, Vasilis; Winkler, Mathias; Whitaker, Hayley C; Ahmed, Hashim U; Emberton, Mark.

Eur Urol ; 78(2): 163-170, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-32370911

11.

Mind the gap? The platform trial as a working environment.

Morrell, Liz; Hordern, Joshua; Brown, Louise; Sydes, Matthew R; Amos, Claire L; Kaplan, Richard S; Parmar, Mahesh K B; Maughan, Timothy S.

Trials ; 20(1): 297, 2019 May 29.

Artigo em Inglês | MEDLINE | ID: mdl-31138284

12.

This is a platform alteration: a trial management perspective on the operational aspects of adaptive and platform and umbrella protocols.

Schiavone, Francesca; Bathia, Riya; Letchemanan, Krishna; Masters, Lindsey; Amos, Claire; Bara, Anna; Brown, Louise; Gilson, Clare; Pugh, Cheryl; Atako, Nafisah; Hudson, Fleur; Parmar, Mahesh; Langley, Ruth; Kaplan, Richard S; Parker, Chris; Attard, Gert; Clarke, Noel W; Gillessen, Silke; James, Nicholas D; Maughan, Tim; Sydes, Matthew R.

Trials ; 20(1): 264, 2019 May 29.

Artigo em Inglês | MEDLINE | ID: mdl-31138317

13.

Pharmacogenetic analyses of 2183 patients with advanced colorectal cancer; potential role for common dihydropyrimidine dehydrogenase variants in toxicity to chemotherapy.

Madi, Ayman; Fisher, David; Maughan, Timothy S; Colley, James P; Meade, Angela M; Maynard, Julie; Humphreys, Vikki; Wasan, Harpreet; Adams, Richard A; Idziaszczyk, Shelley; Harris, Rebecca; Kaplan, Richard S; Cheadle, Jeremy P.

Eur J Cancer ; 102: 31-39, 2018 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-30114658

14.

Role for Nucleotide Excision Repair Gene Variants in Oxaliplatin-Induced Peripheral Neuropathy.

West, Hannah; Coffey, Michelle; Wagner, Michael J; McLeod, Howard L; Colley, James P; Adams, Richard A; Fleck, Oliver; Maughan, Timothy S; Fisher, David; Kaplan, Richard S; Harris, Rebecca; Cheadle, Jeremy P.

JCO Precis Oncol ; 2: 1-18, 2018 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-35135151

15.

Multiparametric MRI to improve detection of prostate cancer compared with transrectal ultrasound-guided prostate biopsy alone: the PROMIS study.

Brown, Louise Clare; Ahmed, Hashim U; Faria, Rita; El-Shater Bosaily, Ahmed; Gabe, Rhian; Kaplan, Richard S; Parmar, Mahesh; Collaco-Moraes, Yolanda; Ward, Katie; Hindley, Richard Graham; Freeman, Alex; Kirkham, Alexander; Oldroyd, Robert; Parker, Chris; Bott, Simon; Burns-Cox, Nick; Dudderidge, Tim; Ghei, Maneesh; Henderson, Alastair; Persad, Rajendra; Rosario, Derek J; Shergill, Iqbal; Winkler, Mathias; Soares, Marta; Spackman, Eldon; Sculpher, Mark; Emberton, Mark.

Health Technol Assess ; 22(39): 1-176, 2018 07.

Artigo em Inglês | MEDLINE | ID: mdl-30040065

16.

Consensus statement on essential patient characteristics in systemic treatment trials for metastatic colorectal cancer: Supported by the ARCAD Group.

Goey, Kaitlyn K H; Sørbye, Halfdan; Glimelius, Bengt; Adams, Richard A; André, Thierry; Arnold, Dirk; Berlin, Jordan D; Bodoky, György; de Gramont, Aimery; Díaz-Rubio, Eduardo; Eng, Cathy; Falcone, Alfredo; Grothey, Axel; Heinemann, Volker; Hochster, Howard S; Kaplan, Richard S; Kopetz, Scott; Labianca, Roberto; Lieu, Christopher H; Meropol, Neal J; Price, Timothy J; Schilsky, Richard L; Schmoll, Hans-Joachim; Shacham-Shmueli, Einat; Shi, Qian; Sobrero, Alberto F; Souglakos, John; Van Cutsem, Eric; Zalcberg, John; van Oijen, Martijn G H; Punt, Cornelis J A; Koopman, Miriam.

Eur J Cancer ; 100: 35-45, 2018 09.

Artigo em Inglês | MEDLINE | ID: mdl-29936065

17.

Age, sex, and racial differences in the use of standard adjuvant therapy for colorectal cancer.

Potosky, Arnold L; Harlan, Linda C; Kaplan, Richard S; Johnson, Karen A; Lynch, Charles F.

J Clin Oncol ; 20(5): 1192-202, 2002 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-11870160

18.

Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: biological and clinical results.

Lang, Frederick F; Bruner, Janet M; Fuller, Gregory N; Aldape, Kenneth; Prados, Michael D; Chang, Susan; Berger, Mitchel S; McDermott, Michael W; Kunwar, Sandeep M; Junck, Larry R; Chandler, William; Zwiebel, James A; Kaplan, Richard S; Yung, W K Alfred.

J Clin Oncol ; 21(13): 2508-18, 2003 Jul 01.

Artigo em Inglês | MEDLINE | ID: mdl-12839017

19.

GNOSIS: guidelines for neuro-oncology: standards for investigational studies-reporting of phase 1 and phase 2 clinical trials.

Chang, Susan M; Reynolds, Sharon L; Butowski, Nicholas; Lamborn, Kathleen R; Buckner, Jan C; Kaplan, Richard S; Bigner, Darell D.

Neuro Oncol ; 7(4): 425-34, 2005 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-16212807

20.

How can we improve clinical trials?

Kaplan, Richard S.

Nat Clin Pract Oncol ; 4(4): 206-7, 2007 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-17392712

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