[Effectiveness of the therapeutic use of complexones in various diseases of the extrapyramidal system in children]. / Ob éffektivnosti lechebnogo primeneniia kompleksonov pri nekotorykh zabolevaniiakh ekstrapiramidnoi sistemy u detei.

The article is devoted to therapy of some extrapyramidal diseases related to accumulation of biomicroelements in the basal ganglia. Two clinical observations (Fahr's disease and Hallervodren-Spatz' disease) in children are described. In both cases therapy with complexones (xydifon, penicillamine, deferoxamine) combined with antioxidants, calcium antagonists, drugs improving the microcirculation, etc., produced a marked positive effect. This was the first case of using complexones for treating Fahr's disease. Possible ways of correcting the metabolism of trace elements in diseases affecting the central nervous system, in particular perspectives of wider application of complexones are discussed.

Effect of Na-,Fe-,Co-,Cu-polygalacturonate on hemopoietic function in laboratory animals.

The effects of water-soluble Na-,Fe-,Co-,Cu-polygalacturonate on hemopoiesis were studied in laboratory animals of various species, age, and functional groups. The compound had a strong positive effect on hemopoiesis, which manifested in an increase in hemoglobin concentration and erythrocyte count and rapid recovery of blood parameters after acute blood loss.

Effect of pectin substances on contractile activity of the uterine myometrium in rats.

We studied the effects of peptides from Amaranthus cruentus L., Rauwolfia serpentina Benth., and citrus plants on contractile activity of the uterine myometrium in rats. Pectin substances inhibited spontaneous contractile activity of uterine muscles and abolished the stimulatory effect of oxytocin. Pectins had a synergistic effect with epinephrine and acetylcholine.