Pesquisa | BVS Violência e Saúde

1.

Evidence for endogenous exchange of cytoplasmic material between a subset of cone and rod photoreceptors within the adult mammalian retina via direct cell-cell connections.

Heisterkamp, Patrick; Borsch, Oliver; Lezama, Nundehui Diaz; Gasparini, Sylvia; Fathima, Adeeba; Carvalho, Livia S; Wagner, Felix; Karl, Mike O; Schlierf, Michael; Ader, Marius.

Exp Eye Res ; 219: 109033, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35288107

2.

Hematopoietic hypoxia-inducible factor 2α deficiency ameliorates pathological retinal neovascularization via modulation of endothelial cell apoptosis.

Korovina, Irina; Neuwirth, Ales; Sprott, David; Weber, Silvio; Sardar Pasha, Sheik Pran Babu; Gercken, Bettina; Breier, Georg; El-Armouche, Ali; Deussen, Andreas; Karl, Mike O; Wielockx, Ben; Chavakis, Triantafyllos; Klotzsche-von Ameln, Anne.

FASEB J ; 33(2): 1758-1770, 2019 02.

Artigo em Inglês | MEDLINE | ID: mdl-30156910

3.

Morpho-Rheological Fingerprinting of Rod Photoreceptors Using Real-Time Deformability Cytometry.

Santos-Ferreira, Tiago; Herbig, Maik; Otto, Oliver; Carido, Madalena; Karl, Mike O; Michalakis, Stylianos; Guck, Jochen; Ader, Marius.

Cytometry A ; 95(11): 1145-1157, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-31107590

4.

Prospective purification and characterization of Müller glia in the mouse retina regeneration assay.

Schäfer, Patrick; Karl, Mike O.

Glia ; 65(5): 828-847, 2017 05.

Artigo em Inglês | MEDLINE | ID: mdl-28220544

5.

Age-dependent Müller glia neurogenic competence in the mouse retina.

Löffler, Kati; Schäfer, Patrick; Völkner, Manuela; Holdt, Tina; Karl, Mike O.

Glia ; 63(10): 1809-24, 2015 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-25943952

6.

The potential of stem cell research for the treatment of neuronal damage in glaucoma.

Karl, Mike O.

Cell Tissue Res ; 353(2): 311-25, 2013 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-23708526

7.

Modeling inducible neuropathologies of the retina with differential phenotypes in organoids.

Völkner, Manuela; Wagner, Felix; Kurth, Thomas; Sykes, Alex M; Del Toro Runzer, Claudia; Ebner, Lynn J A; Kavak, Cagri; Alexaki, Vasileia Ismini; Cimalla, Peter; Mehner, Mirko; Koch, Edmund; Karl, Mike O.

Front Cell Neurosci ; 17: 1106287, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-37213216

8.

Reliability of human retina organoid generation from hiPSC-derived neuroepithelial cysts.

Carido, Madalena; Völkner, Manuela; Steinheuer, Lisa Maria; Wagner, Felix; Kurth, Thomas; Dumler, Natalie; Ulusoy, Selen; Wieneke, Stephanie; Norniella, Anabel Villanueva; Golfieri, Cristina; Khattak, Shahryar; Schönfelder, Bruno; Scamozzi, Maria; Zoschke, Katja; Canzler, Sebastian; Hackermüller, Jörg; Ader, Marius; Karl, Mike O.

Front Cell Neurosci ; 17: 1166641, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-37868194

9.

P53 is required for the developmental restriction in Müller glial proliferation in mouse retina.

Ueki, Yumi; Karl, Mike O; Sudar, Samuel; Pollak, Julia; Taylor, Russell J; Loeffler, Kati; Wilken, Matthew S; Reardon, Sara; Reh, Thomas A.

Glia ; 60(10): 1579-89, 2012 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-22777914

10.

Transplanted human cones incorporate into the retina and function in a murine cone degeneration model.

Gasparini, Sylvia J; Tessmer, Karen; Reh, Miriam; Wieneke, Stephanie; Carido, Madalena; Völkner, Manuela; Borsch, Oliver; Swiersy, Anka; Zuzic, Marta; Goureau, Olivier; Kurth, Thomas; Busskamp, Volker; Zeck, Günther; Karl, Mike O; Ader, Marius.

J Clin Invest ; 132(12)2022 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-35482419

11.

HBEGF-TNF induce a complex outer retinal pathology with photoreceptor cell extrusion in human organoids.

Völkner, Manuela; Wagner, Felix; Steinheuer, Lisa Maria; Carido, Madalena; Kurth, Thomas; Yazbeck, Ali; Schor, Jana; Wieneke, Stephanie; Ebner, Lynn J A; Del Toro Runzer, Claudia; Taborsky, David; Zoschke, Katja; Vogt, Marlen; Canzler, Sebastian; Hermann, Andreas; Khattak, Shahryar; Hackermüller, Jörg; Karl, Mike O.

Nat Commun ; 13(1): 6183, 2022 10 19.

Artigo em Inglês | MEDLINE | ID: mdl-36261438

12.

Stimulation of neural regeneration in the mouse retina.

Karl, Mike O; Hayes, Susan; Nelson, Branden R; Tan, Kristine; Buckingham, Brian; Reh, Thomas A.

Proc Natl Acad Sci U S A ; 105(49): 19508-13, 2008 Dec 09.

Artigo em Inglês | MEDLINE | ID: mdl-19033471

13.

Optimized Adeno-Associated Virus Vectors for Efficient Transduction of Human Retinal Organoids.

Völkner, Manuela; Pavlou, Marina; Büning, Hildegard; Michalakis, Stylianos; Karl, Mike O.

Hum Gene Ther ; 32(13-14): 694-706, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-33752467

14.

Mouse Retinal Organoid Growth and Maintenance in Longer-Term Culture.

Völkner, Manuela; Kurth, Thomas; Schor, Jana; Ebner, Lynn J A; Bardtke, Lara; Kavak, Cagri; Hackermüller, Jörg; Karl, Mike O.

Front Cell Dev Biol ; 9: 645704, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-33996806

15.

A Human Retinal Pigment Epithelium-Based Screening Platform Reveals Inducers of Photoreceptor Outer Segments Phagocytosis.

Schreiter, Sven; Vafia, Katerina; Barsacchi, Rico; Tsang, Stephen H; Bickle, Marc; Ader, Marius; Karl, Mike O; Tanaka, Elly M; Almedawar, Seba.

Stem Cell Reports ; 15(6): 1347-1361, 2020 12 08.

Artigo em Inglês | MEDLINE | ID: mdl-33242397

16.

MERTK-Dependent Ensheathment of Photoreceptor Outer Segments by Human Pluripotent Stem Cell-Derived Retinal Pigment Epithelium.

Almedawar, Seba; Vafia, Katerina; Schreiter, Sven; Neumann, Katrin; Khattak, Shahryar; Kurth, Thomas; Ader, Marius; Karl, Mike O; Tsang, Stephen H; Tanaka, Elly M.

Stem Cell Reports ; 14(3): 374-389, 2020 03 10.

Artigo em Inglês | MEDLINE | ID: mdl-32160519

17.

Endogenous Gas6 and Ca2+ -channel activation modulate phagocytosis by retinal pigment epithelium.

Karl, Mike O; Kroeger, Wolfram; Wimmers, Soenke; Milenkovic, Vladimir M; Valtink, Monika; Engelmann, Katrin; Strauss, Olaf.

Cell Signal ; 20(6): 1159-68, 2008 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-18395422

18.

The Mouse Retinal Organoid Trisection Recipe: Efficient Generation of 3D Retinal Tissue from Mouse Embryonic Stem Cells.

Völkner, Manuela; Kurth, Thomas; Karl, Mike O.

Methods Mol Biol ; 1834: 119-141, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-30324441

19.

Ion channels in the RPE.

Wimmers, Sönke; Karl, Mike O; Strauss, Olaf.

Prog Retin Eye Res ; 26(3): 263-301, 2007 May.

Artigo em Inglês | MEDLINE | ID: mdl-17258931

20.

The light peak of the electroretinogram is dependent on voltage-gated calcium channels and antagonized by bestrophin (best-1).

Marmorstein, Lihua Y; Wu, Jiang; McLaughlin, Precious; Yocom, John; Karl, Mike O; Neussert, Rudgar; Wimmers, Soenke; Stanton, J Brett; Gregg, Ronald G; Strauss, Olaf; Peachey, Neal S; Marmorstein, Alan D.

J Gen Physiol ; 127(5): 577-89, 2006 May.

Artigo em Inglês | MEDLINE | ID: mdl-16636205

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