[The International Classification of Functioning, Disability, and Health in the practice of a sociomedical examination service for internal diseases].

The paper gives the International Classification of Functioning, Disability, and Health (ICF), interactions between health changes, the personality and social factors of an individual with therapeutic diseases to define disability criteria and a scientific rationale for the necessity and scope of rehabilitative measures through public health and social protection organizations.

[Prognostication of results of coronary artery bypass surgery in men living in the North].

We analyzed immediate and remote results of coronary artery bypass surgery and prognostication of outcome of the intervention in dependence on various risk factors in 576 men aged 29 - 71 years living in the North. We formed a model with strong prognostic effect on lethal outcome during in-hospital postoperative period which included the following parameters: perioperative myocardial infarction, complex character of surgery, left ventricular ejection fraction less than 40%, number of distal anastomoses 5 and more, functional class III chronic heart failure. Method of regression analysis revealed factors also related to lethal outcome in period of hospitalization: functional class IV of angina, duration of operation more than 5 hours, mitral insufficiency of 2nd degree and above, myocardial infarction of left ventricular anterior wall, history of 2 or more infarctions. Model with strong prognostic effect on mortality in remote period (3 years after surgery) included the following parameters: left ventricular ejection fraction less than 40%, functional class III chronic heart failure, repeat character of operation, left ventricular aneurysm, lack of use of internal mammary artery. Most significant factors additionally affecting long term mortality were the following: involvement of left coronary artery trunk, duration of surgery more than 5 hours, atherosclerosis of magistral arteries, mitral insufficiency of 2nd degree and above, cardiac rhythm disturbances.

[Interrelations of pulmonary and systemic hemodynamics in hypertension]. / Vzaimootnosheniia legochnoi i sistemnoi gemodinamiki pri gipertonicheskoi bolezni.

A comprehensive study of the systemic and pulmonary hemodynamics, performed in 198 hypertensive patients showed them to have reduced volume of blood circulating in the lungs due to enhanced postcapillary tone. Impairment of arterial blood flow in the lungs and development of pulmonary hypertension fail to keep pace with changes in the systemic circulation.

[Determination of the criteria for selecting the optimal obsidan and hypothiazide treatment regimen in hypertension based on mathematical modelling data]. / Opredeleneie kriteriev dlia vybora optimal'nogo rezhima lecheniia obzidanom i gipotiazidom bol'nykh gipertonicheskoi bolezn'iu po dannym matematicheskogo modelirovaniia.

Criteria for the choice of drug dosage are established. In mild changes of pulmonary hemodynamics in patients with hypertensive disease, minimum doses of hypothiazide are recommended, while treatment should be conducted with obsidan, for the main part. In considerable attendant disorders of pulmonary hemodynamics the dose of hypothiazide should be proportionally increased, while the dose of obsidan is reduced.

[Climatic and ecological risk factors of myocardial infarction in the Far North]. / Klimatoékologicheskie faktory riska ostrogo infarkta miokarda v usloviiakh Krainego Severa.

Basing on analysis of 1383 hospitalizations because of myocardial infarction during 5 years the following climatic events were found to be associated with development of the disease: rapid changes of atmospheric pressure, temperature or humidity, and magnetic storms. Technogenic ecological factors such as levels of formaldehyde, phenol, nitrogen dioxide and carbon monoxide in atmospheric air were also related to frequency of hospitalizations due to myocardial infarction.

[Effect of hypertensive shifts of arterial pressure on bronchial airway resistance]. / Vliianie gipertenzivnykh sdvigov arterial'nogo davleniia na bronkhial'noe soprotivlenie.

Plethysmography of the cat body revealed that occlusion (for 1.5-2.0 min) of carotid arteries caused the hypertension in the major circulation to entail a 10% decrease in the airway resistance against air flow. Obturation of the aorta (for 1.5-2.0 min) caused the pressor of the arterial pressure to develop in conjugation with a 21% increase in the bronchial resistance. The data suggest that in both cases the above shifts of the respiration system are based on opposite changes in the lung congestion with blood (a decrease in the occlusion and an increase in the obturation) which affect the state of bronchi in the peripheral parts of the respiratory tract.

[Arterial hypertension and its treatment in the aged]. / Arterial'naia gipertoniia i ee lechenie u prestarelykh.

The rise of arterial pressure in elderly and senile persons reflects morphological alterations in the vessels, the development of sympathetic hyperactivation and adrenoreceptor dysfunction rather than can be referred to compensatory and adaptation reactions of the body. The treatment of patients suffering from arterial hypertension should be aimed at preventing the development of fibrinoid arterial necrosis which may occur because of regular antihypertensive therapy and dyslipidemia correction.

[The effect of adequate therapy on the indices of external respiratory function in patients with arterial hypertension combined with obstructive lung diseases]. / Vliianie adekvatnoi terapii na pokazateli funktsii vneshnego dykhaniia u bol'nykh arterial'noi gipertoniei v sochetanii s obstruktivnymi zabolevaniiami legkikh.

In patients with associated arterial hypertension and obstructive lung diseases, external respiratory function was established to return to normal thanks to adequate hypotensive therapy and administration of the cholinolytic agents combined with antibacterial and antiinflammatory treatment.