[Current methods of treatment and prevention of pathologic scars]. / A kóros hegek kezelésének és megelozésének lehetoségei napjainkban.

The aetiology of pathologic scarring is unknown today regarding the keloids. The authors have analyzed the literature and own experience retrospectively according to the evidence based treatments and prevention of the hypertrophic and keloid scars. The corticosteroids have been used intralesionally since the beginning of the 1960-ies. It was followed by the pressure garment therapy in order to treat the widespread burns scars in the early 1970-ies. The silicone gel sheeting is being used since the 1980-ies. The basic treatment of keloids changed, radiotherapy was combined with the above mentioned methods because of its high recurrence rate. Newer methods, cryosurgery as well as lasers were used to treat keloids. The number of effective topical agents was increased. The researchers have been looking for other, intralesionally usable medicine and genetic causes for more than ten years. The clinicians have had the standard protocols of the adjunct and alternative methods too. After having the standard and internationally accepted scar assessment system (Vancouver-scar scale and score), the controlled, randomized trials were practicable. The prospective evaluation of the efficacy of different protocols with adequate follow-up became performable. The comparison of different methods is difficult because of the lack of its standard outcome.

[A comparative clinical study of the treatment of hypertrophic scars with either intralaesional steroid or silicone gel sheeting]. / A hypertrophiás hegek intralaesionalis szteroid és polisziloxán-tapaszos kezelésének összehasonlító klinikai vizsgálata.

The linear (or "surgical") hypertrophic scar is the most common type of pathologic scarring. There has been a steady increase in the number of patients with hypertrophic scars over the years due to the rising number of operative interventions altogether. However, the therapeutic protocols are not homogeneous and they show significant variations. 200 cases with hypertrophic scars were treated by the authors from April 2001 to March 2004. 24 patients were selected in the study from these cases; and two randomized groups were formed. Each group included 12-12 patients, who were treated with either intralaesional steroid or silicone gel sheeting. The therapeutic protocols were defined by the authors. The aim of this study was to compare and determine the roles of these two commonly used treatment options of hypertrophic scars. The authors present patient demographics; and analyze the results and outcome of the study. Both methods were efficient significantly, however intralaesional steroid therapy had a more rapid effect and it lasted longer than silicone gel sheeting. These results confirmed the role of these two treatment modalities in the protocols. The authors concluded that silicone gel sheeting is the first line, while intralaesional steroid is the second line treatment for primary linear hypertrophic scars. Based on the authors' experience, in recurrent linear hypertrophic scars, intralaesional steroid therapy is recommended in first line, because silicone gel sheeting was largely ineffective. Prospective randomized clinical trials should be needed to further clarify their role in the treatment protocols.