Detalhe da pesquisa
1.
RBM39: A druggable metabolic sensor linking RNA splicing, transcriptional regulation, and metabolic reprogramming in cancer.
Mol Cell
; 83(23): 4202-4204, 2023 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38065060
2.
Hyperacetylated histone H4 is a source of carbon contributing to lipid synthesis.
EMBO J
; 43(7): 1187-1213, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38383863
3.
Mechanistic safety assessment via multi-omic characterisation of systemic pathway perturbations following in vivo MAT2A inhibition.
Arch Toxicol
; 2024 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38755480
4.
Systems level profiling of chemotherapy-induced stress resolution in cancer cells reveals druggable trade-offs.
Proc Natl Acad Sci U S A
; 118(17)2021 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33883278
5.
Urinary metabolite quantitative trait loci in children and their interaction with dietary factors.
Hum Mol Genet
; 29(23): 3830-3844, 2021 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33283231
6.
Circulating amino acid levels and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition and UK Biobank cohorts.
BMC Med
; 21(1): 80, 2023 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36855092
7.
miR-22-enriched breast cancer cells display repressed glycolytic metabolism, increased glycogen synthesis, and reduced survival in low glucose conditions.
Mol Biol Rep
; 50(6): 5185-5193, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37119413
8.
MicroRNAs as biomarkers for prostate cancer prognosis: a systematic review and a systematic reanalysis of public data.
Br J Cancer
; 126(3): 502-513, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35022525
9.
Simultaneous targeting of glycolysis and oxidative phosphorylation as a therapeutic strategy to treat diffuse large B-cell lymphoma.
Br J Cancer
; 127(5): 937-947, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35618788
10.
Pan-cancer analysis of pre-diagnostic blood metabolite concentrations in the European Prospective Investigation into Cancer and Nutrition.
BMC Med
; 20(1): 351, 2022 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36258205
11.
Variability of multi-omics profiles in a population-based child cohort.
BMC Med
; 19(1): 166, 2021 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34289836
12.
Metabolic signatures of greater body size and their associations with risk of colorectal and endometrial cancers in the European Prospective Investigation into Cancer and Nutrition.
BMC Med
; 19(1): 101, 2021 04 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33926456
13.
Prenatal Exposure to Perfluoroalkyl Substances Associated With Increased Susceptibility to Liver Injury in Children.
Hepatology
; 72(5): 1758-1770, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32738061
14.
Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines.
Metabolomics
; 17(12): 104, 2021 11 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34822010
15.
Prospective analysis of circulating metabolites and endometrial cancer risk.
Gynecol Oncol
; 162(2): 475-481, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34099314
16.
Lactic acidosis induces resistance to the pan-Akt inhibitor uprosertib in colon cancer cells.
Br J Cancer
; 122(9): 1298-1308, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32152504
17.
A case of malignant hyperlactaemic acidosis appearing upon treatment with the mono-carboxylase transporter 1 inhibitor AZD3965.
Br J Cancer
; 122(8): 1141-1145, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32076124
18.
Correction: A case of malignant hyperlactaemic acidosis appearing upon treatment with the mono-carboxylase transporter 1 inhibitor AZD3965.
Br J Cancer
; 122(8): 1272, 2020 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-32203218
19.
In utero and childhood exposure to tobacco smoke and multi-layer molecular signatures in children.
BMC Med
; 18(1): 243, 2020 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32811491
20.
Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines.
Metabolomics
; 16(4): 51, 2020 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32300895