[Local cerebral blood flow, vascular reactivity and intracranial pressure in the very acute period of a cerebral concussion (experimental)]. / Mestnyi mozgovoi krovotok, sosudistaia reaktivnost' v vnutricherepnoe davlenie v ostreishem periode ushiba golovnogo mozga (v éksperimente).

Changes of local cerebral blood flow, vascular reactivity, and intracranial pressure in the first hours after brain contusion in its different areas (hemispheres, brain stem) were studied in experiment. The dynamics of changes of these values and their interrelationship in the first 2 hour after trauma were revealed.

[Craniocerebral trauma and stroke]. / Cherepno-mozgovaia travma i mozgovoi insul't.

It was demonstrated from analysis of 685 cases that craniocerebral injury is attended by the development of secondary acute disorders of cerebral circulation in 8.9% of cases. Cerebral apoplexy is encountered in craniocerebral trauma 4-5 times more frequently (in 25% of cases) among patients with arterial hypertension and 2-2.5 times more frequently (in 12% of cases) among those with diabetes mellitus than in patients with a nonacerbated somatic anamnesis (in 5.4% of cases).

[Redox and proteolytic enzymes in brain tissue after a concussion]. / Okislitel'no-vosstanovitel'nye i proteoliticheskie fermenty v tkani mozga pri ego ushibakh.

The article deals with the results of histochemical study of some redox and proteolytic enzymes (SDH, MDH, NAD-diaphorase, LDH, and acid and alkaline phosphatase) in experiments on animals in various periods after infliction of a craniocerebral injury and on autopsy material, i.e. the brain of patients who had died from severe craniocerebral injury incompatible with life. It is shown that the activity of all enzymes decreases (SDH, MDH, NAD-diaphorase, and alkaline phosphatase) or increases (LDH, acid phosphatase) in various periods after the injury. The results were compared with the findings of morphological examination of the same brain areas performed by means of neurohistological methods.

[Surgical treatment of contusion foci in different age groups]. / Khirurgicheskoe lechenie kontuzionnykh ochagov u postradavshikh razlichnykh vozrastnykh grupp.

The specific features of surgical treatment of contusion foci in patients of various age groups were studied basing on analysis of 606 cases. Two groups of cases were analysed: those with an isolated brain contusion and cases with contusion and compression of the brain by hematoma and bone fragments. It is shown that removal of the contusion foci in patients of various age groups improves the results of treatment. The patient's age has an essential influence on the choice of surgical tactics in brain contusion.

[Dynamic monitoring of the severity of brain edema and swelling by separate impedance measurement in patients with severe craniocerebral trauma]. / Dinamicheskii kontrol' vyrazhennosti oteka i nabukhaniia mozga metodom razdel'noi impedansometrii u bol'nykh s tiazheloi cherepno-mozgovoi travmoi.

The dynamics of brain edema and swelling was studied according to the indices of separate impedancemetry in the early posttraumatic period in 36 patients with severe craniocerebral trauma. Swelling of the brain predominated on the 1st and 2nd days in most patients. Later, depending on the severity of the posttraumatic period, the swelling may grow or be replaced by edema with subsequent normalization. A parallelism was revealed between the severity of brain edema and swelling, the intracranial pressure value, and the severity of the patient's condition.

[Plastic reconstruction fo cranial vault defects]. / Plastika defektov svoda cherepa.

Peculiarities of performance of the reconstructive operation performed in 350 patients at primary surgical treatment, or later on, at the period of primary treatment of a patient at a hospital and at his readmission with the aim of cranioplasty are considered. The authors recommend to perform the reconstructive operation in presence of a cranial vault defect at the time of primary surgical treatment, or 2-5 weeks later, when preparing a patient for such an operation.