Distinctive Roles of Medial Prefrontal Cortex Subregions in Strategic Conformity to Social Hierarchy.

People often align their behaviors and decisions with others' expectations, especially those of higher social positions, when they are being observed. However, little attention has been paid to the neural mechanisms underlying increased conformity to the social hierarchy under social observation. Using a preference rating task, we investigated whether and how individual preferences for novel stimuli were influenced by others' preferences by manipulating others' social hierarchy and observational context. The behavioral results showed that human participants of both sexes were more likely to change their preferences to match those of a superior partner in a public than in a private context. fMRI data revealed distinct contributions of the subregions of the medial prefrontal cortex (mPFC) to increased conformity to social hierarchy under observation. Specifically, the ventral mPFC showed increased activity when participants' preferences aligned with those of superior partners, regardless of behavioral manifestation. The rostral mPFC showed increased activity when conforming to a superior partner and nonconforming to an inferior one, indicating goal-dependent valuation. The dorsal mPFC showed increased activity in private conditions with a superior partner but only in those with a higher tendency to conform. These findings support the hierarchical allostatic regulation model of the mPFC function for social valuation and suggest strategic conformity as a way to minimize metabolic costs.SIGNIFICANCE STATEMENT This study revealed distinct roles of subregions of the mPFC in increased conformity to individuals of different social ranks under observation. Specifically, the ventral mPFC showed increased activity when participants' preferences aligned with those of higher-ranking partners, whereas the rostral mPFC showed increased activity when conforming to a superior partner and nonconforming to an inferior partner, indicating goal-dependent valuation. The dorsal mPFC was more active in private conditions with a superior partner but only in those with a higher tendency to conform. These findings support the hierarchical allostatic regulation model of the mPFC function for social valuation and suggest strategic conformity as a way to minimize metabolic costs.

Coordinated anatomical and functional variability in the human brain during adolescence.

Adolescence represents a time of unparalleled brain development. In particular, developmental changes in morphometric and cytoarchitectural features are accompanied by maturation in the functional connectivity (FC). Here, we examined how three facets of the brain, including myelination, cortical thickness (CT), and resting-state FC, interact in children between the ages of 10 and 15. We investigated the pattern of coordination in these measures by computing correlation matrices for each measure as well as meta-correlations among them both at the regional and network levels. The results revealed consistently higher meta-correlations among myelin, CT, and FC in the sensory-motor cortical areas than in the association cortical areas. We also found that these meta-correlations were stable and little affected by age-related changes in each measure. In addition, regional variations in the meta-correlations were consistent with the previously identified gradient in the FC and therefore reflected the hierarchy of cortical information processing, and this relationship persists in the adult brain. These results demonstrate that heterogeneity in FC among multiple cortical areas are closely coordinated with the development of cortical myelination and thickness during adolescence.

Neural representation in MPFC reveals hidden selfish motivation in white lies.

Identifying true motivation for Pareto lies, which are mutually beneficial for both the liar and others, can be challenging because different covert motivations can lead to identical overt behavior. In this study, we adopted a brain-fingerprinting approach, combining both univariate and multivariate analyses to estimate individual measures of selfish motivation in Pareto lies by the degree of multivoxel neural representation in the medial prefrontal cortex (MPFC) for Pareto lies conforms with those for selfish vs. altruistic lies in human participants of either sex. An increase in selfish motivation for Pareto lies was associated with higher mean-level activity in both ventral and rostral MPFC. The former showed an increased pattern similarity to selfish lies and the latter showed a decreased pattern similarity to altruistic lies. Higher ventral MPFC pattern similarity predicted faster response time in Pareto lies. Our findings demonstrated that hidden selfish motivation in white lies can be revealed by neural representation in the MPFC.SIGNIFICANCE STATEMENT:True motivation for dishonesty serving both self and others cannot be accurately discerned from observed behaviors. Here we showed that fMRI combining both univariate and multivariate analyses can be effectively used to reveal hidden selfish motivation of Pareto lies serving both self and others. The present study suggests that selfish motivation for prosocial dishonesty is encoded primarily by increased activity of the ventromedial and the rostromedial prefrontal cortex, representing intuitive self-serving valuation and strategic switching of motivation depending on beneficiary of dishonesty, respectively.

Neural signatures of individual variability in context-dependent perception of ambiguous facial expression.

How do we incorporate contextual information to infer others' emotional state? Here we employed a naturalistic context-dependent facial expression estimation task where participants estimated pleasantness levels of others' ambiguous expression faces when sniffing different contextual cues (e.g., urine, fish, water, and rose). Based on their pleasantness rating data, we placed participants on a context-dependency continuum and mapped the individual variability in the context-dependency onto the neural representation using a representational similarity analysis. We found that the individual variability in the context-dependency of facial expression estimation correlated with the activity level of the pregenual anterior cingulate cortex (pgACC) and the amygdala and was also decoded by the neural representation of the ventral anterior insula (vAI). A dynamic causal modeling revealed that those with higher context-dependency exhibited a greater degree of the modulation from vAI to the pgACC. These findings provide novel insights into the neural circuitry associated with the individual variability in context-dependent facial expression estimation and the first empirical evidence for individual variability in the predictive accounts of affective states.

The Modulation of Cardiac Vagal Tone on Attentional Orienting of Fair-Related Faces: Low HRV is Associated with Faster Attentional Engagement to Fair-Relevant Stimuli.

The current experiment examined the effect of fair-related stimuli on attentional orienting and the role of cardiac vagal tone indexed by heart rate variability (HRV). Neutral faces were associated with fair and unfair offers in the Ultimatum Game (UG). After the UG, participants performed the spatial cueing task in which targets were preceded by face cues that made fair or unfair offers in the UG. Participants showed faster attentional engagement to fair-related stimuli, which was more pronounced in individuals with lower resting HRV-indexing reduced cardiac vagal tone. Also, people showed delayed attentional disengagement from fair-related stimuli, which was not correlated with HRV. The current research provided initial evidence that fair-related social information influences spatial attention, which is associated with cardiac vagal tone. These results provide further evidence that the difficulty in attentional control associated with reduced cardiac vagal tone may extend to a broader social and moral context.

Rawlsian maximin rule operates as a common cognitive anchor in distributive justice and risky decisions.

Distributive justice concerns the moral principles by which we seek to allocate resources fairly among diverse members of a society. Although the concept of fair allocation is one of the fundamental building blocks for societies, there is no clear consensus on how to achieve "socially just" allocations. Here, we examine neurocognitive commonalities of distributive judgments and risky decisions. We explore the hypothesis that people's allocation decisions for others are closely related to economic decisions for oneself at behavioral, cognitive, and neural levels, via a concern about the minimum, worst-off position. In a series of experiments using attention-monitoring and brain-imaging techniques, we investigated this "maximin" concern (maximizing the minimum possible payoff) via responses in two seemingly disparate tasks: third-party distribution of rewards for others, and choosing gambles for self. The experiments revealed three robust results: (i) participants' distributive choices closely matched their risk preferences-"Rawlsians," who maximized the worst-off position in distributions for others, avoided riskier gambles for themselves, whereas "utilitarians," who favored the largest-total distributions, preferred riskier but more profitable gambles; (ii) across such individual choice preferences, however, participants generally showed the greatest spontaneous attention to information about the worst possible outcomes in both tasks; and (iii) this robust concern about the minimum outcomes was correlated with activation of the right temporoparietal junction (RTPJ), the region associated with perspective taking. The results provide convergent evidence that social distribution for others is psychologically linked to risky decision making for self, drawing on common cognitive-neural processes with spontaneous perspective taking of the worst-off position.

Spatial gradient in value representation along the medial prefrontal cortex reflects individual differences in prosociality.

Despite the importance of valuing another person's welfare for prosocial behavior, currently we have only a limited understanding of how these values are represented in the brain and, more importantly, how they give rise to individual variability in prosociality. In the present study, participants underwent functional magnetic resonance imaging while performing a prosocial learning task in which they could choose to benefit themselves and/or another person. Choice behavior indicated that participants valued the welfare of another person, although less so than they valued their own welfare. Neural data revealed a spatial gradient in activity within the medial prefrontal cortex (MPFC), such that ventral parts predominantly represented self-regarding values and dorsal parts predominantly represented other-regarding values. Importantly, compared with selfish individuals, prosocial individuals showed a more gradual transition from self-regarding to other-regarding value signals in the MPFC and stronger MPFC-striatum coupling when they made choices for another person rather than for themselves. The present study provides evidence of neural markers reflecting individual differences in human prosociality.

Neural evidence for individual and cultural variability in the social comparison effect.

Although several studies have investigated the neural mechanism of social comparison, it remains unclear whether and how cultural membership, particularly independent versus interdependent cultures, may differentially shape the neural processes underlying social comparison. In the present functional magnetic resonance imaging (fMRI) study, we examined the behaviors and neural response patterns of Korean (i.e., interdependent culture) and American (i.e., independent culture) participants while performing a financial gambling task simultaneously and independently with a partner. Upon seeing the partner's income, greater modulation of the activity in the ventral striatum (VS) and the ventromedial prefrontal cortex (vmPFC) by relative gain was observed in Korean than American participants, suggesting greater sensitivity of Koreans toward social comparison. The strength of functional connectivity between the VS and the vmPFC predicted individual variability in the degree to which participants' decisions were affected by relative incomes. Additional model-based fMRI analysis further confirmed the primary role of the vmPFC in biasing decisions based on relative incomes. In summary, the present study provides the first neural evidence for decision biases due to social comparison and their individual and cultural variations.

Lateral OFC activity predicts decision bias due to first impressions during ultimatum games.

Despite the prevalence and potentially harmful consequences of first impression bias during social decision-making, its precise neural underpinnings remain unclear. Here, on the basis of the fMRI study using ultimatum games, the authors show that the responders' decisions to accept or reject offers were significantly affected by facial trustworthiness of proposers. Analysis using a model-based fMRI method revealed that activity in the right lateral OFC (lOFC) of responders increased as a function of negative decision bias, indicating a greater likelihood of rejecting otherwise fair offers, possibly because of the facial trustworthiness of proposers. In addition, lOFC showed changes in functional connectivity strength with amygdala and insula as a function of decision bias, and individual differences in the strengths of connectivities between lOFC and bilateral insula were also found to predict the likelihood of responders to reject offers from untrustworthy-looking proposers. The present findings emphasize that the lOFC plays a pivotal role in integrating signals related to facial impression and creating signal biasing decisions during social interactions.

Overlapping responses for the expectation of juice and money rewards in human ventromedial prefrontal cortex.

Although much is known about the neural substrates of reward, the question of whether expectation of different types of reinforcers engage distinct or overlapping brain circuitry has not been addressed definitively. In the present study, human subjects, while being scanned with functional magnetic resonance imaging, performed a simple reward-based action selection task to obtain different magnitudes of either monetary outcomes (winning or losing money) or juice outcomes (pleasant apple juice or an unpleasant salt flavor). At the group level, we found partially overlapping value-related activity within ventromedial prefrontal cortex (vmPFC) during anticipation of juice and money reward outcomes. Analogous results were found in the right anterior insula, except that this region showed negative correlations as a function of increasing expected reward. These results indicate that vmPFC and anterior insula contain overlapping representations of anticipatory value, consistent with the existence of a common currency for the value of expected outcomes in these regions.

Distinctive roles of mPFC subregions in forming impressions and guiding social interaction based on others' social behaviour.

People can quickly form impressions of others from their social behaviour, which can guide their future social interactions. This study investigated how the type and timing of others' social decisions affect the impression formation and social interactions. In each trial, participants watched a responder's decision in an ultimatum game, decided whether to choose the responder as their next partner for proposer or responder and reported the perceived warmth, competence and likability of the responder. Participants preferred responders who accepted (i.e. accepters) unfair offers for the responder and those who rejected (i.e. rejecters) unfair offers for the proposer in their next ultimatum game, and the rostral medial prefrontal cortex (mPFC) activity encoded such a strategic context-dependent valuation when choosing partners. Slow rejecters were perceived as warmer than fast rejecters, which was mirrored by the anterior mid-cingulate cortex activity when watching others' decisions, possibly detecting and resolving conflicting impressions. Finally, those who perceived accepters vs rejecters as warmer showed higher ventral mPFC responses to accepters vs rejecters when choosing a partner, regardless of the context. The present study suggests that distinctive subregions of the mPFC may be differentially involved in forming impressions and guiding social interactions with others based on their social behaviours.

The relationship between mental representations of self and social evaluation: Examining the validity and usefulness of visual proxies of self-image.

Reverse correlation (RC) method has been recently used to visualize mental representations of self. Previous studies have mainly examined the relationship between psychological aspects measured by self-reports and classification images of self (self-CIs), which are visual proxies of self-image generated through the RC method. In Experiment 1 (N = 118), to extend the validity of self-CIs, we employed social evaluation on top of self-reports as criterion variables and examined the relationship between self-CIs and social evaluation provided by clinical psychologists. Experiment 1 revealed that the valence ratings of self-CIs evaluated by independent raters predicted social evaluation after controlling for the effects of self-reported self-esteem and extraversion. Furthermore, in Experiment 2 (N = 127), we examined whether a computational scoring method - a method to assess self-CIs without employing independent raters - could be applied to evaluate the valence of participants' self-CIs. Experiment 2 found that the computational scores of self-CIs were comparable to independent valence ratings of self-CIs. We provide evidence that self-CIs can add independent information to self-reports in predicting social evaluation. We also suggest that the computational scoring method can complement the independent rating process of self-CIs. Overall, our findings reveal that self-CIs are a valid and useful tool to examine self-image more profoundly.

Ingroup favoritism overrides fairness when resources are limited.

Ingroup favoritism and fairness are two potentially competing motives guiding intergroup behaviors in human. Here, we investigate if and how limited resources can modulate the way these two motives affect individuals' decisions in intergroup situation. In the present study, participants (N = 58) were asked to accept or reject three types of resource allocation proposals generated by a computer: the ingroup advantageous condition, outgroup advantageous condition, and neutral condition. In general, participants were more willing to accept the proposals in the ingroup advantageous condition than the outgroup advantageous or the neutral conditions, and also in the moderate inequality than the extreme inequality condition. This may indicate that people sought a careful balance between ingroup favoritism and fairness, although we also found marked individual differences in their preferences for ingroup favoritism or fairness. Importantly, as predicted, participants were more likely to show ingroup favoritism only when limited resources affect the well-being of ingroup members. The present study provides novel insights into the situational and personality factors affecting human intergroup behaviors, shedding light on motives underlying intergroup conflicts prevalent in human societies.

Moral parochialism and causal appraisal of transgressive harm in Seoul and Los Angeles.

The evolutionary fitness payoffs of moral condemnation are greatest within an individual's immediate social milieu. Accordingly, insofar as human moral intuitions have been shaped by adaptive design, we can expect transgressive harms to be perceived as more wrong when transpiring in the here and now than when occurring at a distance, or with the approval of local authority figures. This moral parochialism hypothesis has been supported by research conducted in diverse societies, but has yet to be tested in an East Asian society, despite prior research indicating that East Asians appraise transgressive acts as being caused by situational and contextual factors to a greater extent than do Westerners, who tend to emphasize dispositional factors (i.e., the transgressor's personal nature). Here, in a quasi-experiment using field samples recruited in Seoul and Los Angeles, we tested (i) the moral parochialism hypothesis regarding the perceived wrongness of transgressions, as well as (ii) the extent to which these wrongness judgments might be influenced by cross-cultural differences in causal appraisals. Despite notably large differences across the two societies in situational versus dispositional appraisals of the causes of the transgressions, replicating previous findings elsewhere, in both societies we found that transgressions were deemed less wrong when occurring at spatial or temporal remove or with the consent of authorities. These findings add to the understanding of morality as universally focused on local affairs, notwithstanding cultural variation in perceptions of the situational versus dispositional causes of (im)moral acts.

Roles of the MPFC and insula in impression management under social observation.

People often engage in impression management by presenting themselves and others as socially desirable. However, specific behavioral manifestations and underlying neural mechanisms of impression management remain unknown. In this study, we investigated the neural mechanism of impression management during self- and friend-evaluation. Only participants assigned to the observation (OBS) group, not the control (CON) group, were informed that their responses would be monitored. They answered how well positive and negative trait adjectives described themselves or their friends. The behavioral results showed that the OBS group was more likely to reject negative traits for self-evaluation and to accept positive traits for friend-evaluation. An independent study revealed that demoting negative traits for oneself and promoting positive traits for a friend helps manage one's impression. In parallel with the behavioral results, in the OBS vs the CON group, the rostromedial prefrontal cortex (rmPFC) and anterior insula (AI) activity showed a greater increase as the negativity of negatively valenced adjectives increased during self-evaluation and also showed a greater increase as the positivity of positively valenced adjectives increased during friend-evaluation. The present study suggests that rmPFC and AI are critically involved in impression management, promoting socially desirable target evaluations under social observation.

Increased Conformity to Social Hierarchy Under Public Eyes.

Why would people conform more to others with higher social positions? People may place higher confidence in the opinions of those who rank higher in the social hierarchy, or they may wish to make better impressions on people of higher social status. We investigated how individual preferences for novel stimuli are influenced by the preferences of others in the social hierarchy and whether anonymity affects such preference changes. After manipulation of their social rank, participants were asked to indicate how much they liked or disliked a series of images. Then, they were shown the rating given to each image by a partner (either inferior or superior in social rank) and were given a chance to adjust their ratings. The participants were more likely to change their preferences to match those of a superior partner in the public vs. private condition. The tendency to conform to the views of the superior partner was stronger among those with higher social dominance orientation (SDO) and those with greater fear of negative evaluation (FNE) by others. Altogether, the findings suggest that the motivation to make better impressions on people of higher social status can be the major driver of conformity to others with higher social positions.

"Older adults consider others' intentions less but allocentric outcomes more than young adults during an ultimatum game": Correction to Cho et al. (2020).

Reports an error in "Older adults consider others' intentions less but allocentric outcomes more than young adults during an ultimatum game" by Isu Cho, Hyun-joo Song, Hackjin Kim and Sunhae Sul (Psychology and Aging, 2020[Nov], Vol 35[7], 974-980). In the original article, there was a typographical error in the grant number awarded to Hyun-joo Song. The correct grant number is NRF-2018S1A3A2075114. The online version of this article has been corrected. (The following abstract of the original article appeared in record 2020-68198-001). The present research investigated age-related differences in other-regarding preferences-the preference for taking others' benefit into account during social decision-making-between young and elderly adults. Young and older Korean adults responded to multiple rounds of a mini-ultimatum game, and the extent to which each individual considered outcome and intention was quantified using economic utility models. We found that older adults, compared to young adults, were less likely to consider others' intentions, while focusing more on others' outcomes. Possible psychological factors underlying our findings, including theory of mind, prosocial values, and decision strategies, are discussed. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Effects of Oxytocin on Social Comparisons in Intergroup Situations.

Oxytocin (OXT) is known to affect various social processes, including social comparisons and intergroup competition. In this study, we examined whether social comparisons in intergroup situations can be modulated by OXT and, if so, how this modulation manifests. Using a double-blind placebo-controlled design, we randomly assigned male participants to either OXT or placebo treatment and then asked them to play a card game with either an in-group or an out-group member. The OXT-treated participants showed a greater social comparison effect in the games with an out-group member than in games with an in-group member. Specifically, the participants in the OXT treatment condition showed a greater acceptance rate for relative gain (downward comparison) and a lower acceptance rate for relative loss (upward comparison) while playing with an out-group member rather than an in-group member. In contrast, no such effect was observed among placebo-treated participants. These findings demonstrate that OXT facilitates intergroup social comparisons with out-group versus in-group members.

Temporal isolation of neural processes underlying face preference decisions.

Decisions about whether we like someone are often made so rapidly from first impressions that it is difficult to examine the engagement of neural structures at specific points in time. Here, we used a temporally extended decision-making paradigm to examine brain activation with functional MRI (fMRI) at sequential stages of the decision-making process. Activity in reward-related brain structures-the nucleus accumbens (NAC) and orbitofrontal cortex (OFC)-was found to occur at temporally dissociable phases while subjects decided which of two unfamiliar faces they preferred. Increases in activation in the OFC occurred late in the trial, consistent with a role for this area in computing the decision of which face to choose. Signal increases in the NAC occurred early in the trial, consistent with a role for this area in initial preference formation. Moreover, early signal increases in the NAC also occurred while subjects performed a control task (judging face roundness) when these data were analyzed on the basis of which of those faces were subsequently chosen as preferred in a later task. The findings support a model in which rapid, automatic engagement of the NAC conveys a preference signal to the OFC, which in turn is used to guide choice.

Stability or Plasticity? - A Hierarchical Allostatic Regulation Model of Medial Prefrontal Cortex Function for Social Valuation.

The medial prefrontal cortex (mPFC) has long been recognized as the key component of the neurocircuitry involved in various social as well as non-social behaviors, however, little is known regarding the organizing principle of distinctive subregions in the mPFC that integrates a wide range of mPFC functions. The present study proposes a hierarchical model of mPFC functionality, where three functionally dissociable subregions, namely, the ventromedial prefrontal cortex (vmPFC), rostromedial prefrontal cortex (rmPFC), and dorsomedial prefrontal cortex (dmPFC), are differentially involved in computing values of decision-making. According to this model, the mPFC subregions interact with each other in such a way that more dorsal regions utilize additional external sensory information from environment to predict and prevent conflicts occurring in more ventral regions tuned to internal bodily signals, thereby exerting the hierarchically organized allostatic regulatory control over homeostatic reflexes. This model also emphasizes the role of the thalamic reticular nucleus (TRN) in arbitrating the transitions between different thalamo-cortical loops, detecting conflicts between competing options for decision-making, and in shifting flexibly between decision modes. The hierarchical architecture of the mPFC working in conjunction with the TRN may play a key role in adjusting the internal (bodily) needs to suit the constraints of external (environmental) variables better, thus effectively addressing the stability-plasticity dilemma.