Detalhe da pesquisa
1.
Structure of the complement C5a receptor bound to the extra-helical antagonist NDT9513727.
Nature
; 553(7686): 111-114, 2018 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29300009
2.
Extra-helical binding site of a glucagon receptor antagonist.
Nature
; 533(7602): 274-7, 2016 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27111510
3.
Tau-tubulin kinase 1 phosphorylates TDP-43 at disease-relevant sites and exacerbates TDP-43 pathology.
Neurobiol Dis
; 161: 105548, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34752923
4.
Preparation of purified GPCRs for structural studies.
Biochem Soc Trans
; 41(1): 185-90, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23356281
5.
Opportunities for therapeutic antibodies directed at G-protein-coupled receptors.
Nat Rev Drug Discov
; 16(9): 787-810, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28706220
6.
Antibodies targeting G protein-coupled receptors: Recent advances and therapeutic challenges.
MAbs
; 9(5): 735-741, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28475474
7.
The expression pattern of nitric oxide-sensitive guanylyl cyclase in the rat heart changes during postnatal development.
J Histochem Cytochem
; 50(10): 1325-32, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12364565
8.
Biliverdin IX is an endogenous inhibitor of soluble guanylyl cyclase.
Biochem Pharmacol
; 64(1): 109-16, 2002 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12106611
9.
Native human nitric oxide sensitive guanylyl cyclase: purification and characterization.
Biochem Pharmacol
; 67(8): 1579-85, 2004 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15041475
10.
Monoclonal anti-ß1-adrenergic receptor antibodies activate G protein signaling in the absence of ß-arrestin recruitment.
MAbs
; 6(1): 246-61, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24253107
11.
Biophysical fragment screening of the ß1-adrenergic receptor: identification of high affinity arylpiperazine leads using structure-based drug design.
J Med Chem
; 56(9): 3446-55, 2013 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23517028
12.
Opportunities for therapeutic antibodies directed at G-protein-coupled receptors.
Nat Rev Drug Discov
; 16(9): 661, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28860586
13.
The amino-terminus of nitric oxide sensitive guanylyl cyclase α1 does not affect dimerization but influences subcellular localization.
PLoS One
; 6(9): e25772, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21984946
14.
Therapeutic antibodies directed at G protein-coupled receptors.
MAbs
; 2(6): 594-606, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20864805
15.
Characterization of 16 human G protein-coupled receptors expressed in baculovirus-infected insect cells.
Protein Expr Purif
; 44(1): 65-74, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15951199
16.
A functional domain of the alpha1 subunit of soluble guanylyl cyclase is necessary for activation of the enzyme by nitric oxide and YC-1 but is not involved in heme binding.
J Biol Chem
; 278(14): 12590-7, 2003 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-12560334
17.
BAY 41-2272 activates two isoforms of nitric oxide-sensitive guanylyl cyclase.
Biochem Biophys Res Commun
; 292(4): 1057-62, 2002 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-11944922