Detalhe da pesquisa
1.
Bile salt hydrolase catalyses formation of amine-conjugated bile acids.
Nature
; 626(8000): 859-863, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38326609
2.
Gut bacteria alleviate smoking-related NASH by degrading gut nicotine.
Nature
; 610(7932): 562-568, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36261549
3.
Estrogen-Related Receptor Agonism Reverses Mitochondrial Dysfunction and Inflammation in the Aging Kidney.
Am J Pathol
; 193(12): 1969-1987, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37717940
4.
Intestinal peroxisome proliferator-activated receptor α-fatty acid-binding protein 1 axis modulates nonalcoholic steatohepatitis.
Hepatology
; 77(1): 239-255, 2023 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35460276
5.
The role of FXR and TGR5 in reversing and preventing progression of Western diet-induced hepatic steatosis, inflammation, and fibrosis in mice.
J Biol Chem
; 298(11): 102530, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36209823
6.
Postprandial Plasma Lipidomics Reveal Specific Alteration of Hepatic-derived Diacylglycerols in Nonalcoholic Fatty Liver Disease.
Gastroenterology
; 162(7): 1990-2003, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35283114
7.
Caffeic acid phenethyl ester suppresses intestinal FXR signaling and ameliorates nonalcoholic fatty liver disease by inhibiting bacterial bile salt hydrolase activity.
Acta Pharmacol Sin
; 44(1): 145-156, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-35655096
8.
Myelocytomatosis-Protein Arginine N-Methyltransferase 5 Axis Defines the Tumorigenesis and Immune Response in Hepatocellular Carcinoma.
Hepatology
; 74(4): 1932-1951, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33896016
9.
St. John's Wort alleviates dextran sodium sulfate-induced colitis through pregnane X receptor-dependent NFκB antagonism.
FASEB J
; 35(11): e21968, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34644426
10.
Bile acid sequestration reverses liver injury and prevents progression of nonalcoholic steatohepatitis in Western diet-fed mice.
J Biol Chem
; 295(14): 4733-4747, 2020 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32075905
11.
Metabolomic profiling of metoprolol hypertension treatment reveals altered gut microbiota-derived urinary metabolites.
Hum Genomics
; 14(1): 10, 2020 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32160915
12.
Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity.
Xenobiotica
; 51(9): 1047-1059, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34319859
13.
Intestinal PPARα Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6.
Gastroenterology
; 157(3): 744-759.e4, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31154022
14.
Withaferin A Improves Nonalcoholic Steatohepatitis in Mice.
J Pharmacol Exp Ther
; 371(2): 360-374, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31420528
15.
Intestine farnesoid X receptor agonist and the gut microbiota activate G-protein bile acid receptor-1 signaling to improve metabolism.
Hepatology
; 68(4): 1574-1588, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29486523
16.
FXR/TGR5 Dual Agonist Prevents Progression of Nephropathy in Diabetes and Obesity.
J Am Soc Nephrol
; 29(1): 118-137, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29089371
17.
Extrahepatic PPARα modulates fatty acid oxidation and attenuates fasting-induced hepatosteatosis in mice.
J Lipid Res
; 59(11): 2140-2152, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30158201
18.
Farnesoid X receptor induces Takeda G-protein receptor 5 cross-talk to regulate bile acid synthesis and hepatic metabolism.
J Biol Chem
; 292(26): 11055-11069, 2017 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28478385
19.
Metabolic Profiling of the Novel Hypoxia-Inducible Factor 2α Inhibitor PT2385 In Vivo and In Vitro.
Drug Metab Dispos
; 46(4): 336-345, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29363499
20.
Glycyrrhizin Alleviates Nonalcoholic Steatohepatitis via Modulating Bile Acids and Meta-Inflammation.
Drug Metab Dispos
; 46(9): 1310-1319, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29959134