Detalhe da pesquisa
1.
Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis.
Cell
; 173(1): 260-274.e25, 2018 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29551266
2.
Non-genetic determinants of malignant clonal fitness at single-cell resolution.
Nature
; 601(7891): 125-131, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34880496
3.
HBO1 is required for the maintenance of leukaemia stem cells.
Nature
; 577(7789): 266-270, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31827282
4.
CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity.
Nature
; 549(7670): 101-105, 2017 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28813417
5.
BET inhibitor resistance emerges from leukaemia stem cells.
Nature
; 525(7570): 538-42, 2015 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26367796
6.
Comparative cofactor screens show the influence of transactivation domains and core promoters on the mechanisms of transcription.
Nat Genet
; 56(6): 1181-1192, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38769457
7.
CRISPR-ChIP reveals selective regulation of H3K79me2 by Menin in MLL leukemia.
Nat Struct Mol Biol
; 30(10): 1592-1606, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37679565
8.
Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity.
Cancer Discov
; 13(10): 2228-2247, 2023 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37548590
9.
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes.
Nat Cell Biol
; 25(2): 258-272, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36635503
10.
CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
Cell Rep
; 42(8): 113014, 2023 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37605534
11.
Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death.
Cancer Discov
; 12(3): 774-791, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34862195
12.
Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses.
Cancer Cell
; 40(10): 1190-1206.e9, 2022 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36179686
13.
BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation.
Sci Adv
; 7(22)2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34039605
14.
CDK4/6 inhibition reprograms the breast cancer enhancer landscape by stimulating AP-1 transcriptional activity.
Nat Cancer
; 2(1): 34-48, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33997789
15.
Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation.
Science
; 368(6489): 387-394, 2020 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32193360
16.
An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer.
Cancer Cell
; 36(4): 385-401.e8, 2019 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31564637
17.
Dynamic molecular monitoring reveals that SWI-SNF mutations mediate resistance to ibrutinib plus venetoclax in mantle cell lymphoma.
Nat Med
; 25(1): 119-129, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30455436
18.
CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
Cell Rep
; 43(2): 113793, 2024 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38324452
19.
Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia.
Nat Commun
; 10(1): 2723, 2019 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31222014
20.
Click chemistry enables preclinical evaluation of targeted epigenetic therapies.
Science
; 356(6345): 1397-1401, 2017 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28619718