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1.
J Opt Soc Am A Opt Image Sci Vis ; 33(10): 2089-2098, 2016 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-27828118

RESUMO

Since distortions in camera-captured document images significantly affect the accuracy of optical character recognition (OCR), distortion removal plays a critical role for document digitalization systems using a camera for image capturing. This paper proposes a novel framework that performs three-dimensional (3D) reconstruction and rectification of camera-captured document images. While most existing methods rely on additional calibrated hardware or multiple images to recover the 3D shape of a document page, or make a simple but not always valid assumption on the corresponding 3D shape, our framework is more flexible and practical since it only requires a single input image and is able to handle a general locally smooth document surface. The main contributions of this paper include a new iterative refinement scheme for baseline fitting from connected components of text line, an efficient discrete vertical text direction estimation algorithm based on convex hull projection profile analysis, and a 2D distortion grid construction method based on text direction function estimation using 3D regularization. In order to examine the performance of our proposed method, both qualitative and quantitative evaluation and comparison with several recent methods are conducted in our experiments. The experimental results demonstrate that the proposed method outperforms relevant approaches for camera-captured document image rectification, in terms of improvements on both visual distortion removal and OCR accuracy.

2.
Nat Commun ; 11(1): 3329, 2020 07 03.
Artigo em Inglês | MEDLINE | ID: mdl-32620839

RESUMO

Human gut microbiota plays critical roles in physiology and disease. Our understanding of ecological principles that govern the dynamics and resilience of this highly complex ecosystem remains rudimentary. This knowledge gap becomes more problematic as new approaches to modifying this ecosystem, such as fecal microbiota transplantation (FMT), are being developed as therapeutic interventions. Here we present an ecological framework to understand the efficacy of FMT in treating conditions associated with a disrupted gut microbiota, using the recurrent Clostridioides difficile infection as a prototype disease. This framework predicts several key factors that determine the efficacy of FMT. Moreover, it offers an efficient algorithm for the rational design of personalized probiotic cocktails to decolonize pathogens. We analyze data from both preclinical mouse experiments and a clinical trial of FMT to validate our theoretical framework. The presented results significantly improve our understanding of the ecological principles of FMT and have a positive translational impact on the rational design of general microbiota-based therapeutics.


Assuntos
Infecções por Clostridium/terapia , Transplante de Microbiota Fecal/métodos , Fezes/microbiologia , Microbioma Gastrointestinal/fisiologia , Algoritmos , Animais , Clostridioides difficile/fisiologia , Infecções por Clostridium/microbiologia , Humanos , Camundongos , Modelos Teóricos , Recidiva , Resultado do Tratamento
3.
IEEE Trans Image Process ; 25(3): 1368-81, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26829791

RESUMO

Local binary patterns (LBP) are considered among the most computationally efficient high-performance texture features. However, the LBP method is very sensitive to image noise and is unable to capture macrostructure information. To best address these disadvantages, in this paper, we introduce a novel descriptor for texture classification, the median robust extended LBP (MRELBP). Different from the traditional LBP and many LBP variants, MRELBP compares regional image medians rather than raw image intensities. A multiscale LBP type descriptor is computed by efficiently comparing image medians over a novel sampling scheme, which can capture both microstructure and macrostructure texture information. A comprehensive evaluation on benchmark data sets reveals MRELBP's high performance-robust to gray scale variations, rotation changes and noise-but at a low computational cost. MRELBP produces the best classification scores of 99.82%, 99.38%, and 99.77% on three popular Outex test suites. More importantly, MRELBP is shown to be highly robust to image noise, including Gaussian noise, Gaussian blur, salt-and-pepper noise, and random pixel corruption.

4.
PLoS One ; 10(8): e0135282, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26281042

RESUMO

Recent advances indicate that assigning or reversing edge direction can significantly improve the structural controllability of complex networks. For directed networks, approaching the optimal structural controllability can be achieved by detecting and reversing certain "inappropriate" edge directions. However, the existence of multiple sets of "inappropriate" edge directions suggests that different edges have different effects on optimal controllability-that is, different combinations of edges can be reversed to achieve the same structural controllability. Therefore, we classify edges into three categories based on their direction: critical, redundant and intermittent. We then investigate the effects of changing these edge directions on network controllability, and demonstrate that the existence of more critical edge directions implies not only a lower cost of modifying inappropriate edges but also better controllability. Motivated by this finding, we present a simple edge orientation method aimed at producing more critical edge directions-utilizing only local information-which achieves near optimal controllability. Furthermore, we explore the effects of edge direction on the controllability of several real networks.


Assuntos
Simulação por Computador , Algoritmos
5.
Artigo em Inglês | MEDLINE | ID: mdl-25375546

RESUMO

Recently, as the controllability of complex networks attracts much attention, how to design and optimize the controllability of networks has become a common and urgent problem in the field of controlling complex networks. Previous work focused on the structural perturbation and neglected the role of edge direction to optimize the network controllability. In a recent work [Phys. Rev. Lett. 103, 228702 (2009)], the authors proposed a simple method to enhance the synchronizability of networks by assignment of link direction while keeping network topology unchanged. However, the controllability is fundamentally different from synchronization. In this work, we systematically propose the definition of assigning direction to optimize controllability, which is called the edge orientation for optimal controllability problem (EOOC). To solve the EOOC problem, we construct a switching network and transfer the EOOC problem to find the maximum independent set of the switching network. We prove that the principle of our optimization method meets the sense of unambiguity and optimum simultaneously. Furthermore, the relationship between the degree-degree correlations and EOOC are investigated by experiments. The results show that the disassortativity pattern could weaken the orientation for optimal controllability, while the assortativity pattern has no correlation with EOOC. All the experimental results of this work verify that the network structure determines the network controllability and the optimization effects.

6.
IEEE Trans Image Process ; 23(7): 3071-84, 2014 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-24860030

RESUMO

In this paper, we propose a simple, efficient, yet robust multiresolution approach to texture classification-binary rotation invariant and noise tolerant (BRINT). The proposed approach is very fast to build, very compact while remaining robust to illumination variations, rotation changes, and noise. We develop a novel and simple strategy to compute a local binary descriptor based on the conventional local binary pattern (LBP) approach, preserving the advantageous characteristics of uniform LBP. Points are sampled in a circular neighborhood, but keeping the number of bins in a single-scale LBP histogram constant and small, such that arbitrarily large circular neighborhoods can be sampled and compactly encoded over a number of scales. There is no necessity to learn a texton dictionary, as in methods based on clustering, and no tuning of parameters is required to deal with different data sets. Extensive experimental results on representative texture databases show that the proposed BRINT not only demonstrates superior performance to a number of recent state-of-the-art LBP variants under normal conditions, but also performs significantly and consistently better in presence of noise due to its high distinctiveness and robustness. This noise robustness characteristic of the proposed BRINT is evaluated quantitatively with different artificially generated types and levels of noise (including Gaussian, salt and pepper, and speckle noise) in natural texture images.

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