Detalhe da pesquisa
1.
Intrinsic bias at non-canonical, ß-arrestin-coupled seven transmembrane receptors.
Mol Cell
; 81(22): 4605-4621.e11, 2021 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34582793
2.
Prostaglandin F2α and angiotensin II type 1 receptors exhibit differential cognate G protein coupling regulation.
J Biol Chem
; 298(9): 102294, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35872018
3.
Key phosphorylation sites in GPCRs orchestrate the contribution of ß-Arrestin 1 in ERK1/2 activation.
EMBO Rep
; 21(9): e49886, 2020 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32715625
4.
The conformational signature of ß-arrestin2 predicts its trafficking and signalling functions.
Nature
; 531(7596): 665-8, 2016 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-27007854
5.
Pharmacological Characterization of the Imipridone Anticancer Drug ONC201 Reveals a Negative Allosteric Mechanism of Action at the D2 Dopamine Receptor.
Mol Pharmacol
; 100(4): 372-387, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34353882
6.
Angiotensin II type 1 receptor variants alter endosomal receptor-ß-arrestin complex stability and MAPK activation.
J Biol Chem
; 295(38): 13169-13180, 2020 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32703898
7.
Genetic code expansion and photocross-linking identify different ß-arrestin binding modes to the angiotensin II type 1 receptor.
J Biol Chem
; 294(46): 17409-17420, 2019 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31530642
8.
Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor phosphorylation in airway contraction.
Proc Natl Acad Sci U S A
; 113(16): 4524-9, 2016 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27071102
9.
ß-Arrestin-mediated Angiotensin II Signaling Controls the Activation of ARF6 Protein and Endocytosis in Migration of Vascular Smooth Muscle Cells.
J Biol Chem
; 291(8): 3967-81, 2016 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26703465
10.
Quantifying biased signaling in GPCRs using BRET-based biosensors.
Methods
; 92: 5-10, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25890247
11.
Angiotensin II type I and prostaglandin F2α receptors cooperatively modulate signaling in vascular smooth muscle cells.
J Biol Chem
; 290(5): 3137-48, 2015 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25512374
12.
Differential regulation of endosomal GPCR/ß-arrestin complexes and trafficking by MAPK.
J Biol Chem
; 289(34): 23302-17, 2014 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25016018
13.
Investigation of the active turn geometry for the labour delaying activity of indolizidinone and azapeptide modulators of the prostaglandin F2α receptor.
Org Biomol Chem
; 13(28): 7750-61, 2015 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26090777
14.
T cell-induced airway smooth muscle cell proliferation via the epidermal growth factor receptor.
Am J Respir Cell Mol Biol
; 49(4): 563-70, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23656597
15.
Unraveling allostery within the angiotensin II type 1 receptor for Gαq and ß-arrestin coupling.
Sci Signal
; 16(797): eadf2173, 2023 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37552769
16.
Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system.
Nat Commun
; 14(1): 4808, 2023 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37558722
17.
Essential role of endocytosis of the type II transmembrane serine protease TMPRSS6 in regulating its functionality.
J Biol Chem
; 286(33): 29035-29043, 2011 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21724843
18.
An interaction between L-prostaglandin D synthase and arrestin increases PGD2 production.
J Biol Chem
; 286(4): 2696-706, 2011 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21112970
19.
Standardized Cannabis Smoke Extract Induces Inflammation in Human Lung Fibroblasts.
Front Pharmacol
; 13: 852029, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35418857
20.
Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity.
Nat Commun
; 13(1): 7428, 2022 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36460632