RESUMO
A salient feature of motor and sensory circuits in the brain is their contralateral hemispheric bias-a feature that might play a role in integration and learning of sensorimotor skills. In the current behavioral study, we examined whether the lateral configuration between sound-producing hand and feedback-receiving ear affects performance and learning of an audio-motor skill. Right-handed participants (n = 117) trained to play a piano sequence using their right or left hand while auditory feedback was presented monaurally, either to the right or left ear. Participants receiving auditory feedback to the contralateral ear during training performed better than participants receiving ipsilateral feedback (with respect to the training hand). Furthermore, in the Left-Hand training groups, the contralateral training advantage persisted in a generalization task. Our results demonstrate that audio-motor learning is sensitive to the lateral configuration between motor and sensory circuits and suggest that integration of neural activity across hemispheres facilitates such learning.