Detalhe da pesquisa
1.
Ceramide analog C2-cer induces a loss in insulin sensitivity in muscle cells through the salvage/recycling pathway.
J Biol Chem
; 299(6): 104815, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37178918
2.
Fish oil minimises feed intake and improves insulin sensitivity in Zucker fa/fa rats.
Br J Nutr
; 131(5): 749-761, 2024 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37877265
3.
Circulating Sphingolipids and Glucose Homeostasis: An Update.
Int J Mol Sci
; 24(16)2023 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37628901
4.
Stearoyl CoA desaturase is a gatekeeper that protects human beta cells against lipotoxicity and maintains their identity.
Diabetologia
; 63(2): 395-409, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31796987
5.
Sphingolipid Metabolism: New Insight into Ceramide-Induced Lipotoxicity in Muscle Cells.
Int J Mol Sci
; 20(3)2019 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30678043
6.
Protective role of the ELOVL2/docosahexaenoic acid axis in glucolipotoxicity-induced apoptosis in rodent beta cells and human islets.
Diabetologia
; 61(8): 1780-1793, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29754287
7.
Lipoprotein lipase in hypothalamus is a key regulator of body weight gain and glucose homeostasis in mice.
Diabetologia
; 60(7): 1314-1324, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28456865
8.
The suppression of hepatic glucose production improves metabolism and insulin sensitivity in subcutaneous adipose tissue in mice.
Diabetologia
; 59(12): 2645-2653, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27631137
9.
Role of palmitate-induced sphingoid base-1-phosphate biosynthesis in INS-1 ß-cell survival.
Biochim Biophys Acta
; 1831(2): 251-62, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23085009
10.
Role of Sphingosine Kinase 1 in Glucolipotoxicity-Induced Early Activation of Autophagy in INS-1 Pancreatic ß Cells.
Cells
; 13(7)2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38607078
11.
Interesterified palm oil promotes insulin resistance and altered insulin secretion and signaling in Swiss mice.
Food Res Int
; 177: 113850, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38225125
12.
Hepatic deletion of serine palmitoyl transferase 2 impairs ceramide/sphingomyelin balance, bile acids homeostasis and leads to liver damage in mice.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1868(8): 159333, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37224999
13.
Ceramide synthase 4 and de novo production of ceramides with specific N-acyl chain lengths are involved in glucolipotoxicity-induced apoptosis of INS-1 ß-cells.
Biochem J
; 438(1): 177-89, 2011 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21592087
14.
Serum ceramides could predict durable diabetes remission following gastric bypass surgery.
Med
; 3(7): 440-441, 2022 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35809557
15.
Homocysteine Metabolism Pathway Is Involved in the Control of Glucose Homeostasis: A Cystathionine Beta Synthase Deficiency Study in Mouse.
Cells
; 11(11)2022 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35681432
16.
cAMP-secretion coupling is impaired in diabetic GK/Par rat ß-cells: a defect counteracted by GLP-1.
Am J Physiol Endocrinol Metab
; 301(5): E797-806, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21750265
17.
Role of hypothalamic de novo ceramides synthesis in obesity and associated metabolic disorders.
Mol Metab
; 53: 101298, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34273578
18.
Ovarian insufficiency impairs glucose-stimulated insulin secretion through activation of hypothalamic de novo ceramide synthesis.
Metabolism
; 123: 154846, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34371064
19.
Identification of the Interactions Interference Between the PH and START Domain of CERT by Limonoid and HPA Inhibitors.
Front Mol Biosci
; 7: 603983, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33330630
20.
Sphingolipid Metabolism and Signaling in Skeletal Muscle: From Physiology to Physiopathology.
Front Endocrinol (Lausanne)
; 11: 491, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32849282