RESUMO
42 patients with bronchial asthma underwent combined treatment according to 8 methods of classical Chinese medicine. Partial and complete immediate and long-term responses were achieved in 81% of the patients with asthma diagnosed by Chinese criteria as cold and mixed. Satisfactory results were recorded in 19% of hot bronchial asthma cases.
Assuntos
Asma/terapia , Medicina Tradicional Chinesa , Adolescente , Adulto , Asma/diagnóstico , Asma/fisiopatologia , Doença Crônica , Terapia Combinada , Estudos de Avaliação como Assunto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Indução de Remissão , Estações do AnoAssuntos
Corticosteroides/sangue , Asma/sangue , Ovário/fisiopatologia , 11-Hidroxicorticosteroides/sangue , Asma/fisiopatologia , Dexametasona , Estradiol/sangue , Feminino , Homeostase/fisiologia , Humanos , Hidrocortisona/sangue , Ciclo Menstrual/fisiologia , Progesterona/sangue , Transcortina/análiseRESUMO
Altered bronchial sensitivity and reactivity are the basis of different variations of bronchospasm. In addition to exogenous agents, endogenous regulation factors such as adrenal and ovarian hormones are believed to make an important contribution to their development. Asthmatics showed the lowest sensitivity and the highest hyperreactivity to acetylcholine as compared to patients with preasthmatic conditions or chronic bronchitis and healthy consanguins of asthmatic patients. Disturbances of glucocorticoid homeostasis, related to various (adrenal, extra-adrenal (transcortin) and cellular) mechanisms of corticosteroid insufficiency, occurred in the majority of asthmatics and asthmatic bronchitis patients. Identification of various mechanisms of glucocorticoid insufficiency opens up actual approaches to increasing the efficiency of an individual therapy.