Detalhe da pesquisa
1.
CD19-CD28: an affinity-optimized CD28 agonist for combination with glofitamab (CD20-TCB) as off-the-shelf immunotherapy.
Blood
; 143(21): 2152-2165, 2024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38437725
2.
Comparative assessment of immune complex-mediated hypersensitivity reactions with biotherapeutics in the non-human primate: Critical parameters, safety and lessons for future studies.
Regul Toxicol Pharmacol
; 88: 125-137, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28624430
3.
Biodistribution of Drug/ADA Complexes: The Impact of Immune Complex Formation on Antibody Distribution.
AAPS J
; 26(2): 33, 2024 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38478197
4.
ROCKETS - a novel one-for-all toolbox for light sheet microscopy in drug discovery.
Front Immunol
; 14: 1034032, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36845124
5.
Clearance of therapeutic antibody glycoforms after subcutaneous and intravenous injection in a porcine model.
MAbs
; 14(1): 2145929, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36383465
6.
Translating pharmacology models effectively to predict therapeutic benefit.
Drug Discov Today
; 27(6): 1604-1621, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35304340
7.
Glycoform-resolved pharmacokinetic studies in a rat model employing glycoengineered variants of a therapeutic monoclonal antibody.
MAbs
; 13(1): 1865596, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33382957
8.
The impact of immunogenicity on therapeutic antibody pharmacokinetics: A preclinical evaluation of the effect of immune complex formation and antibody effector function on clearance.
MAbs
; 13(1): 1995929, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34763611
9.
In Vivo Reoxidation Kinetics of Free Thiols in Multiple Domains of IgG1 Antibodies in Rats.
J Pharm Sci
; 110(5): 1989-1996, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33617870
10.
Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity.
Clin Cancer Res
; 27(14): 4036-4053, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33771854
11.
Vaccination trial with HPV16 L1E7 chimeric virus-like particles in women suffering from high grade cervical intraepithelial neoplasia (CIN 2/3).
Int J Cancer
; 121(12): 2794-800, 2007 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17721997
12.
Efficacy of oncolytic herpesvirus NV1020 can be enhanced by combination with chemotherapeutics in colon carcinoma cells.
Hum Gene Ther
; 17(12): 1241-53, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17117895
13.
Characterization of a re-engineered, mesothelin-targeted Pseudomonas exotoxin fusion protein for lung cancer therapy.
Mol Oncol
; 10(8): 1317-29, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27507537
14.
Immunopurification and mass spectrometric quantification of the active form of a chimeric therapeutic antibody in human serum.
Anal Chem
; 80(5): 1737-45, 2008 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18225864
15.
Immunization with hepatitis C virus-like particles protects mice from recombinant hepatitis C virus-vaccinia infection.
Proc Natl Acad Sci U S A
; 100(11): 6753-8, 2003 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-12748380