Evaluating Lead Halide Perovskite Nanocrystals as a Spin Laser Gain Medium.

Spin-polarized charge endows conventional lasers with not only new functionalities but also reduced lasing thresholds thanks to the lifting of spin degeneracy. II-VI and III-V semiconductors have been extensively investigated as spin laser gain mediums; however, the degree of polarization is limited by the light hole and heavy hole degeneracy. Herein, we evaluate the potential of CsPbBr3 nanocrystals─ones that are featured with low band-edge degeneracy and therefore a high degree of polarization as a result of inverted band structure and large spin-orbit coupling─as a gain medium for spin lasers. Our experiment and numerical modeling results reveal that, within the spin relaxation lifetime, the optical gain threshold can be depressed by polarizing the charge using circularly polarized photoexcitation. However, prolonging the spin relaxation lifetime is required to realize a spin laser.

Prediction of Outlet Pressure for the Sulfur Dioxide Blower Based on Conv1D-BiGRU Model and Genetic Algorithm.

The sulfur dioxide blower is a centrifugal blower that transports various gases in the process of acid production with flue gas. Accurate prediction of the outlet pressure of the sulfur dioxide blower is quite significant for the process of acid production with flue gas. Due to the internal structure of the sulfur dioxide blower being complex, its mechanism model is difficult to establish. A novel method combining one-dimensional convolution (Conv1D) and bidirectional gated recurrent unit (BiGRU) is proposed for short-term prediction of the outlet pressure of sulfur dioxide blower. Considering the external factors such as inlet pressure and inlet flow rate of the blower, the proposed method first uses Conv1D to extract periodic and local correlation features of these external factors and the blower's outlet pressure data. Then, BiGRU is used to overcome the complexity and nonlinearity in prediction. More importantly, genetic algorithm (GA) is used to optimize the important hyperparameters of the model. Experimental results show that the combined model of Conv1D and BiGRU optimized by GA can predict the outlet pressure of sulfur dioxide blower accurately in the short term, in which the root mean square error (RMSE) is 0.504, the mean absolute error (MAE) is 0.406, and R-square (R 2) is 0.993. Also, the proposed method is superior to LSTM, GRU, BiLSTM, BiGRU, and Conv1D-BiLSTM.

New anti-inflammatory 4-hydroxyisoflavans from Solanum lyratum.

Three new 4-hydroxyisoflavans, named lyratin A (1), lyratin B (2) and lyratin C (3), along with a known compound, 4,7,2'trihydroxy-4'-methoxyisoflavan (4), were isolated from the whole plant of Solanum lyratum. Their structures were established by means of detailed physical data analyses. In vitro, four compounds showed anti-inflammatory activities with inhibitory ratios of release of beta-glucuronidase from polymorphonuclear leukocytes of rats in the range of 30.3-38.6% at 10 microM.

[HPLC fingerprint spectrum of honey-fried Radix Glycyrrhizae].

OBJECTIVE: To establish the HPLC fingerprint of the pieces of honey-fried Radix Glycyrrhizae. METHOD: Using the reverse-performance liquid chromatography, method was performed on a Hyperclone ODS C18 column (4.6 mm x 250 mm, 5 microm) and acetonitrile-0.1% phosphoric acid was selected as mobile phase gradient elution were adopted. RESULT: Established HPLC fingerprint of Radix et Rhizoma glycyrrhizae pieces were established, and the results of methodological study met the technical requirements for fingerprinting. CONCLUSION: The HPLC method is stable, accurate, and reliable to provide a scientific basis of quality control standard for the honey-fried Radix et Rhizoma glycyrrhizae.

[Isoflavones from vines of Pueraria lobata].

OBJECTIVE: To investigate the isoflavones from the vines of Pueraria lobata. METHOD: The compounds were isolated by column chromatography over silica gel and RP-C18, and purified by Sephadex LH-20 column chromatography and preparative TLC. The structures were elucidated on the basis of physico-chemical properties and spectral data. RESULT: Twelve compounds were isolated and identified as: 3'-methoxydaidzein (1), formononetin (2), genistein (3), daidzein (4), daidzin (5), genistin (6), ononin (7), 5-hydroxyl ononin (8), calycosin (9), 6"-O-acetyl genistein (10), 6"-O-acetyl daidzin (11), puerarin (12). CONCLUSION: For the first time, compounds 9-11 were isolated from the genus Pueraria plant, and compounds 1, 3, 6-8 were obtained from the vines of this plant.

[Effect on mouse S180 MDR tumour cell expression correlated factorial matter by 70% ethanol with Huanglian Jiedu Tang].

OBJECTIVE: To observe the effect on P170, LRP, TOPO II of S180 tumour MDR mice for matter by 70% ethanol with Huanglian Jiedu Tang, and then discuss the molecular biology base for clinic. METHOD: 18-22 gramme mice were divided into four groups for normal S180 tumour cell group, matter by 70% ethanol with Huanglian Jiede Tang 100 mg x kg(-1) and 50 mg x kg(-1) in random. Each mouse was given S180 cell 0.2 mL by celiac, and after 24 hours give cisplatin for Injective 3 mg x kg(-1), ip, once a week. And give cyclophosphamide and 5-FU 3 mg x kg(-1), ig, once every day. After 15 days, collect lively mice ascites and give it for onefold normal mice. And then repeat before process. At the same time, every group was given corresponding medicine for 0.2 mL x 10 g(-1). The normal group and the model group were given the same cubage water, all together fore weeks. At last observd the P170, LRP, TOPO II by flow cytometry. RESULT: Matter by 70% ethanol with Huanglian Jiedu Tang could obviously reduce the express of P170 and LRP, and the activiation of TOPO II. CONCLUSION: Matter by 70% ethanol with Huanglian Jiedu Tang can intervene the ocurrence of the multi-drug resistance of tumour cells by regulating the biology gene.

[Study of matrine's use on the reversion of obtained multi-drug resistance of mice S80 tumour cell].

OBJECTIVE: To Observe the effect caused by matrine's used on the reversion of obtained multi-drug resistance of mice S180's tumour cell induced by chemotherapy of Cisplatin + 5-FU + Cytoxan (PFC) and discuss its molecular mechanism. METHODS: Patterned the methods of PFC chemotherapy in clinic, the mice were given Cisplatim 3 mg/kg x ip once a week and Cytoxan, CTX and 5-FU 3 mg/kg x ip once everyday for 4 weeks to set up the mice models of multi-drug resistance of S180 tumor cell. At the same time, gave the mice models matrine 4 weeks, and observed the P170, LRP, TOPO II by flow cytometry. RESULTS: matrine could obviously reduce the express of P170, LRP and the activiation of TOPO II, correlated with mulit-drug resistance tumour cells which were induced by chemotherapy. CONCLUSION: Matrine, with its adjustment of correlated biotic active matter, can intervene the ocurrence of the multidrug resistance of tumor cells induced by chemotherapy.

[The interference in correlated molecular mechanism obtained multi-drug resistance of mouse S180's tumour cell for different alkaloid].

OBJECTIVE: To observe the base of the interference in correlated biotic active matter obtained multi-drug resistance induced by chemotherapy for different alkaloid, and to supervise the use in clinic to restrain the multi-drug resistant of chemotherapy, and thereby to improve the curative effect. METHOD: After bestowing subter-dosage unite chemotherapeutant to ascites S180 mouse to set up the mouse models of multi-drug resistance of S180 tumour cell, and giving the mouse matrine, terandrine, oxymatrine and berberine hydrooh loride for 4 weeks, the P170, LRP, TOPOII, Fas and apoposis were determined by flow cytometry. RESULT: Matrine and terandrine could obviously reduce the express of P170, LRP and the activation of TOPOII, and increase the ratio of the express of Fas and the apoposis of drug resistant tumour cell. And at the same time it could obviously reduce the express of intercellular adhesion molecule(CD54). CONCLUSION: Matrine and terandrine can interfere in MDR which results from chemotherapeutics by the adjustment of correlated biotic active matter, besides, the different degree of alkaloid effect with different configuration.

[The study of tetrandrine on reversion of P170 and apoptosis of obtained multi-drug resistance of mice S180's tumour cell].

OBJECTIVE: To observe the effect of tetrandrine on reversion of mice S180's obtained multi-drug resistance tumor cell induced by chemotherapy by PFC. And then discuss the molecular mechanism of it for the use of TCM in clinic to restrain the drug-resistant of chemotherapy, thereby improve the curative effect. METHOD: By the methods of less dosage of chemotherapy PFC, give the mouse cisplatin 3 mg x kg(-1) i.p., once a week; CTX and 5-FU 3 mg x kg(-1) i.g. four weeks, set up the mice models of multi-drug resistance of S180 tumor cell, and then observe the P170, Fas, CD54 and apoposis by flow cytometry. RESULT: Tetrandrine can obviously lower the express of P170 increase the express of Fas and the apoposis of drug resistant tumor cell. And at the same time it can obviously reduce the express of intercellular adhesion molecule (CD54). CONCLUSION: Terandrine, with its adjustment of correlated biotic active matter, can intervene the occurrence of the multi-drug resistance of tumor cells induced by chemotherapy.

[The effect of tetrandrine on the expression of the P170, LRP and TOPO II in S180's tumor cell induced by chemotherapy in the mice with acquired multi-drug resistance].

OBJECTIVE: To observe the effect of tetrandrine on the P170 production expressed by multi-drug resistance gene, lung resistant protein (LRP), and topoisomeras II and elucidate the underlying molecular mechanism. METHOD: Cellular model of multi-drug resistance was established in S180 tumor cell by means of the scheme of PFC chemotherapy at the dosage lower than that with curative effect. P170, LRP and TOPO II were measured by flow cytometry after the mouse model was treated with tetrandrine for 4 weeks. RESULT: tetrandrine obviously reduced the enhancement of express of P170, LRP and the activity of TOPO II in the tumor cells with multi-drug resistance induced by chemotherapy. CONCLUSION: Tetrandrine significantly inhibits the multi-drug resistance of tumor cells induced by chemotherapy via diminishing both the expression of multi-drug resistance gene and the activity of topoisomeras II.

[Comparative study between montmorillonite and Smecta on anti-dysentery effect].

OBJECTIVE: To compare the efficiency of montmorillonite (Mengtuoshi) and Smecta. METHODS: The effects on the dysentery mice induced by MgSO4, rhubarb powder and castor oil, were observed by given respectively 15.6%, 31.2% Mengtuoshi and 31.2% Smecta. And the effects on the over-contracted rabbit intestines were also observed. RESULTS: Both Mengtuoshi and Smecta could relieve the over pushing speeding of stomach and intestine, and reduce the times of dysentery. CONCLUSION: The anti-dysentery effect of Mengtuoshi was similar to Smecta from France and may be used as good anti-dysentery drug.

[The effect of matrine on the expression of P170 LRP and TOPO II of obtained multi-drug resistance of mouse S180's tumour cell].

OBJECTIVE: To observe the effect of matrine on P170 expressed by multi-drug resistance gene, lung resistant protein (LRP), and boposomeras II. METHODS: By the method of less dosage of chemotherapy PFC, the mouse model of multi-drug resistance of S180 tumour cell was set up. At the same time, matrine was administered to the mouse model for 4 weeks, and then P170 LRP, TOPO II were observed by flow cytometry. RESULTS: Martine can obviously reduce the express of P170, LRP and the activity of TOPO II in multi-drug resistance tumour cell induced by chemotherapy. CONCLUSION: Matrine can intervene the occurrence of the multi-drug resitance of tumor cells induced by chemotherapy.

[Speciation and distribution characters of rare earth elements in the Baotou Section of the Yellow River].

As a whole of water column, suspended matter and surface sediment in the mainstream and the branch taking up industry wastewater, speciation and distribution characters of rare earth elements (REEs) were investigated systemically in the Baotou section of the Yellow River. This study shows that rare earth elements in the mainstream of the Baotou section of the Yellow River mainly exist in suspended particles, and the dissolved contents are in extremely minute quantities. REEs mainly exist in dissolved particles in the branch taking up industry wastewater, and suspended sigma REE and dissolved sigma REE are obviously higher than those in the mainstream. The change of sigma REE of dissolved particles in water phase along the Baotou section of the Yellow River is very similar to that of sigma REE of suspended particles, and consistent along the main river, it is that sigma REE increase appreciably from the control profile to the keystone discharged section, come to a head in the D site and reduce in the E site. This distribution pattern indicates pile industry wastewater of Baotou to rare earth elements in the mainstream of the Yellow River, particularly LREE. The REE distribution in the mainstream of the Baotou section of the Yellow River is the same, with LREE enrichment and Eu depletion. But LREE origin of D site is different from the other sites by excursion of LREE distribution curve and other geochemical parameters, they are origin of industry wastewater piled, otherwise the other four sites are origin of loess altiplano. And HREE are origin of loess altiplano in all the sites. The speciation characteristics of REE in the sediments and suspended matter are quite similar with the amount in as follows: residual >> bound to carbonates, bound to Fe-Mn oxides > bound to organic matter >> exchangeable. REEs exchangeable in surface sediment and suspended matter in the branch taking up industry wastewater are higher than those in the mainstream, it confirms that REEs in the mainstream mainly exist in suspended particles, and mainly exist in dissolved particles in the branch.