[Stiffness of the arterial wall and predicted vascular age as a predictor of cardiovascular disease when stress-induced hypertension in the military personnel].

Stiffness of the arterial wall and predicted vascular age as a predictor of cardiovascular disease when stress-induced hypertension in the military personnel. On the basis of the study of 156 men aged 30-55 years are considered diagnostic methods for stress-induced hypertension in the military personnel. Furthermore, using modern diagnostic methods determined stress effect on the development of stress-induced hypertension, and also the risk of cardiovascular diseases. In order to detect early signs of atherosclerosis used sphygmography, by means of which was determined by cardio ankle vascular index (CA VI), as well as the calculated vascular age. The study proposed a set of organizational, diagnostic and therapeutic measures to reduce the risk of cardiovascular diseases among military personnel exposed to occupational stressful load.

[Principles of antihypertensive therapy in metabolic syndrome].

Clinical features of arterial hypertension in patients with metabolic syndrome are described with reference to antihypertensive therapy and the choice of adequate drugs for the purpose. Characteristics of the most frequently used preparations are presented along with algorithms for their application depending on clinical condition. Advantages of combined antihypertensive therapy in metabolic syndrome are substantiated, their most efficacious combinations are recommended.

[Antihypertensive therapy in the elderly patients with metabolic syndrome].

The article is concerned with modern methods of assessment of arterial hypertension in patients with metabolic syndrome and characteristics of modern antihypertensive drugs and its combinations necessary for the elderly. The authors gave their own example of treatment of more than 2000 patients with arterial hypertension and metabolic syndrome.

[Correction of anxiety and psychosomatic disorders in a clinic for former combatants].

Psychological personality disorder among former combatants and their relationship to subsequent psychosomatic disorders are examined. For this purpose, in health centers performed clinical and psychological examination of 105 fighters and 100 military personnel who were not taking part in hostilities (control group) aged 27 to 40 years, three groups are outlined: low (24.7%), moderate (64.8%) and high (10.5%) anxiety level, represented by their clinical characteristics. Studies have shown that combat stress can contribute to postreaktive change not only the psyche combatant, but also the development of persistent psychosomatic disorders. The methods and results of treatment and preventive advice are given.

[Detectability of acute forms of coronary heart disease in real clinical practice].

The study was designed to evaluate the frequency of inapparent and/or unrecorded cases of acute coronary heart disease (CHD) and its influence on overall estimates of CHD mortality and morbidity. A specially developed algorithm was used to identify unrecorded cases in official medical documentation concerning 285,736 subjects. Their fraction was found to be 20.78 and 24.48% among men and women respectively. 89.43% of them died from acute CHD. Addition of the newly identified cases to official statistics increased overall CHD morbidity rates by 26.24 and 32.41% for men and women and mortality rates by 2.13 and 2.28 times respectively. These data indicate that acute CHD is poorly diagnosed in routine clinical practice and the real CHD mortality rate is grossly underestimated.

[Assessment of safety and antihypertensive efficacy of a cardioselective beta-blocker nebivolol in patients with hypertension and concomitant chronic obstructive bronchitis]. / Otsenka bezopasnosti primeneniia i antigipertenzivnaia éffektivnost' beta1-kardioselektivnogo adrenoblokatora nebivolola u bol'nykh s arterial'noi gipertenziei v sochetanii s khronicheskim obstruktivnym bronkhitom.

Safety, tolerability and antihypertensive efficacy of a cardioselective beta-blocker nebivolol was studied in 30 patients with mild and moderate hypertension and concomitant stage I chronic obstructive bronchitis. Nebivolol (5 mg/day) was given for 1 month; in 5 patients complementary hydrochlorothiazide (12.5 mg/day) was required for sufficient antihypertensive effect. Nebivolol was well tolerated (only 1 patient complained of head ache), did not cause worsening of bronchitis and spirometric parameters, exerted no cardiodepressive action, and did not induce apparent disturbances of metabolism.