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1.
Mediators Inflamm ; 2014: 963096, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25538378

RESUMO

Pentraxin-3 (PTX3) is an inflammatory marker thought to be more specific to cardiovascular inflammation than C-reactive protein (CRP). Our aim was to assess the prognostic value of PTX3 in patients with stable coronary artery disease (CAD) after drug eluting stent (DES) implantation. Plasma PTX3 levels were measured before percutaneous coronary intervention (PCI) and at 24 h post-PCI in 596 consecutive patients with stable CAD. Patients were followed up for a median of 3 years (range 1-5) for major adverse cardiovascular events (MACEs). We found that the post-PCI plasma PTX3 levels were significantly higher at 24 h after PCI than pre-PCI, patients with MACEs had higher post-PCI PTX3 levels compared with MACEs-free patients, patients with higher post-PCI PTX3 levels (median > 4.384 ng/mL) had a higher risk for MACEs than those with PTX3 < 4.384 ng/mL, and post-PCI PTX3, cTnI, multiple stents, and age but not high-sensitivity CRP (hsCRP) were independently associated with the prevalence of MACEs after DES implantation. The present study shows that post-PCI PTX3 may be a more reliable inflammatory predictor of long-term MACEs in patients with stable CAD undergoing DES implantation than CRP. Measurement of post-PCI PTX3 levels could provide a rationale for risk stratification of patients with stable CAD after DES implantation.


Assuntos
Proteína C-Reativa/metabolismo , Doença da Artéria Coronariana/sangue , Stents Farmacológicos , Componente Amiloide P Sérico/metabolismo , Idoso , Feminino , Seguimentos , Humanos , Inflamação/metabolismo , Estimativa de Kaplan-Meier , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Paclitaxel/administração & dosagem , Intervenção Coronária Percutânea , Prognóstico , Sirolimo/administração & dosagem , Sirolimo/análogos & derivados
2.
J Tradit Chin Med ; 42(5): 833-838, 2022 10.
Artigo em Inglês | MEDLINE | ID: mdl-36083493

RESUMO

OBJECTIVE: To evaluate the diagnostic efficacy of Qisexingtai hand diagnostic method in the diagnosis of coronary artery disease (CAD). METHODS: This was an investigator-initiated, prospective, multi-center, cross-sectional study. All the participants from three hospitals in China had been diagnosed by both Qisexingtai hand diagnostic method and coronary angiography. We compared the two diagnostic methods to calculate the sensitivity, the specificity, the omission diagnostic rate, the mistaken diagnostic rate and accuracy in order to evaluate the diagnostic efficacy of Qisexingtai hand diagnostic method for CAD. RESULTS: A total of 326 subjects were enrolled, diagnosed by both Qisexingtai hand diagnostic method and coronary angiography. As a result, there were 166 positive cases according to Qisexingtai hand diagnostic method, and 131 positive cases according to coronary angiography. Compared with the results of coronary angiography, the sensitivity of Qisexingtai hand dia-gnostic method was 80.2%, the specificity was 68.7%, the omission diagnostic rate was 19.8%, the mistaken diagnostic rate was 31.3%, and the accuracy was 73.3%. Area under the receiver operating characteristic curve was estimated as 0.735 for all, and 0.718, 0.735, 0.783 for the three sub-centers. CONCLUSION: Qisexingtai hand diagnostic method with high accuracy and sensitivity has certain application value in the diagnosis of CAD.


Assuntos
Doença da Artéria Coronariana , China , Angiografia Coronária/métodos , Doença da Artéria Coronariana/diagnóstico por imagem , Estudos Transversais , Humanos , Estudos Prospectivos
3.
Conf Proc IEEE Eng Med Biol Soc ; 2005: 4072-5, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-17281127

RESUMO

With the increasing performance of computer, the virtual instrument technology has greatly advanced over the years, and then virtual medical instrument technology becomes available. This paper presents the virtual medical instrument, and then as an example, an application of a signal acquisition, processing and analysis system using LabVIEW is also given.

4.
Conf Proc IEEE Eng Med Biol Soc ; 2005: 6056-9, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-17281643

RESUMO

To cure brain paralysis this paper has briefly summarized the rudimentary knowledge of the ultrasonic therapy, and briefly introduced the methods of dolphin ultrasonic therapy, through the research of the dolphin ultrasonic therapy, the ultrasonic frequency chart wave band which is more efficient to the therapy of brain paralysis is measured, and one method of simulated dolphin therapy mechanism is found. Finally, one of the ultrasonic therapy instruments against brain paralysis is developed.

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