Detalhe da pesquisa
1.
Metal complexes bearing EGFR-inhibiting ligands as promising anticancer agents.
Med Res Rev
; 44(4): 1545-1565, 2024 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-38279970
2.
Induction of immunogenic cell death by novel platinum-based anticancer agents.
Pharmacol Res
; 187: 106556, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36403722
3.
SERD-NHC-Au(I) complexes for dual targeting ER and TrxR to induce ICD in breast cancer.
Pharmacol Res
; 190: 106731, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36933755
4.
Recent development of gold(I) and gold(III) complexes as therapeutic agents for cancer diseases.
Chem Soc Rev
; 51(13): 5518-5556, 2022 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35699475
5.
A Gold(I) Complex Containing an Oleanolic Acid Derivative as a Potential Anti-Ovarian-Cancer Agent by Inhibiting TrxR and Activating ROS-Mediated ERS.
Chemistry
; 26(31): 7092-7108, 2020 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32037581
6.
Discovery of a Potent GLUT Inhibitor from a Library of Rapafucins by Using 3D Microarrays.
Angew Chem Int Ed Engl
; 58(48): 17158-17162, 2019 11 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31591797
7.
Design, synthesis and preliminary structure-activity relationship investigation of nitrogen-containing chalcone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors: a further study based on Flavokawain B Mannich base derivatives.
J Enzyme Inhib Med Chem
; 31(4): 580-9, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26186269
8.
Synthesis and acetylcholinesterase inhibitory activity of Mannich base derivatives flavokawain B.
Bioorg Med Chem Lett
; 24(19): 4749-4753, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25205193
9.
Design, synthesis and pharmacological evaluation of chalcone derivatives as acetylcholinesterase inhibitors.
Bioorg Med Chem
; 22(21): 6124-33, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25260958
10.
Metal N-heterocyclic carbene complexes as potential antitumor metallodrugs.
Chem Soc Rev
; 42(2): 755-73, 2013 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23147001
11.
Simultaneous Activation of Immunogenic Cell Death and cGAS-STING Pathway by Liver- and Mitochondria-Targeted Gold(I) Complexes for Chemoimmunotherapy of Hepatocellular Carcinoma.
J Med Chem
; 67(3): 1982-2003, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38261008
12.
A terbium(III) complex-based time-resolved luminescent probe for selenocysteine as an inhibitor of selenoproteins.
Chem Commun (Camb)
; 60(11): 1440-1443, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38206371
13.
Drug conjugates for the treatment of lung cancer: from drug discovery to clinical practice.
Exp Hematol Oncol
; 13(1): 26, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38429828
14.
Discovery of novel quinoline scaffold selective estrogen receptor degraders (SERDs) for treatment of ER positive breast cancer with enhanced antiproliferative bioactivity through immunogenic cell death (ICD) effects.
Eur J Med Chem
; 275: 116534, 2024 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38870830
15.
Research Progress on Bioactive Metal Complexes against ER-Positive Advanced Breast Cancer.
J Med Chem
; 66(4): 2235-2256, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36780448
16.
Tumor-Targeting NHC-Au(I) Complex Induces Immunogenic Cell Death in Hepatocellular Carcinoma.
J Med Chem
; 66(6): 3934-3952, 2023 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36827091
17.
NSAID-Au(I) Complexes Induce ROS-Driven DAMPs and Interpose Inflammation to Stimulate the Immune Response against Ovarian Cancer.
J Med Chem
; 66(12): 7813-7833, 2023 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37291753
18.
Design, synthesis and biological evaluation of fluorinated selective estrogen receptor degraders (FSERDs) --- A promising strategy for advanced ER positive breast cancer.
Eur J Med Chem
; 253: 115324, 2023 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37019030
19.
Gold(I) selenium N-heterocyclic carbene complexes as potent antibacterial agents against multidrug-resistant gram-negative bacteria via inhibiting thioredoxin reductase.
Redox Biol
; 60: 102621, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36758467
20.
A chromosome-level genome assembly reveals that a bipartite gene cluster formed via an inverted duplication controls monoterpenoid biosynthesis in Schizonepeta tenuifolia.
Mol Plant
; 16(3): 533-548, 2023 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36609143